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Squawka / NFL News / 49ers vs Cowboys Prediction & Tips: Week 10

49ers vs Cowboys Prediction & Tips: Week 10

San Francisco 49ers vs Dallas Cowboys prediction, picks and odds for Week 10 of the 2026 NFL season

San Francisco score 3.9 touchdowns a game and convert 84.6% in the red zone, both the best figures in the NFL. Dallas concede 48.3% on third down, the worst. Our 49ers vs Cowboys prediction is the league’s best offence against its most generous defence.

The San Francisco 49ers are 7-1 at +79. The Dallas Cowboys are 4-5 and have conceded 236 points in nine games.

Week 10 · Editorial pick

49ers vs Cowboys: our editor’s props

Two editorial selections to sit with the live Signal read below.

49ers AT Cowboys

Our props

Player propSan Francisco 3+ touchdownsSan Francisco score 3.9 a game and convert 84.6% in the red zone, both the best in the NFL.
★★★★☆4/5 confidence
Player propDak Prescott 250+ passing yardsDallas throw for 257 a game and Prescott had 335 last week. San Francisco concede 211.
★★★☆☆3/5 confidence

An editorial call, not a Signal model output. 18+ | BeGambleAware.org

49ers vs Cowboys: 2026 form so far

The best offence in football against a defence that cannot get off the field. The columns put each side’s output next to what the other has conceded so far.

49ers attack against the Cowboys defence

Per game49ers offenceCowboys allow
Passing yards241.5225.2
Rushing yards135.2147.4
Yards per carry4.65.0
Passer rating109.899.1
Touchdowns3.93.0
Third-down conversion51.7%48.3%
Red-zone conversion84.6%67.6%
Sacks conceded / recorded1.01.9

Cowboys attack against the 49ers defence

Per gameCowboys offence49ers allow
Passing yards256.9211.0
Rushing yards103.680.9
Yards per carry4.03.3
Passer rating95.388.7
Touchdowns3.11.9
Third-down conversion45.3%40.4%
Red-zone conversion71.4%48.0%
Sacks conceded / recorded1.61.9

Dallas concede 48.3% on third down, the highest rate in the NFL, and 147 rushing yards a game, which is 31st.

San Francisco 49ers 7-1 · average margin +9.9

+10−10+20−20Week 1: beat the Rams 27-7 (away)@LA1Week 2: beat the Dolphins 35-13 (home)vMIA2Week 3: beat the Cardinals 36-30 (home)vARI3Week 4: beat the Broncos 24-14 (home)vDEN4Week 5: beat the Seahawks 32-29 (away)@SEA5Week 6: beat the Commanders 23-17 (home)vWAS6Week 7: lost to the Falcons 20-29 (away)@ATL7Week 9: beat the Raiders 38-17 (home)vLV9

Dallas Cowboys 4-5 · average margin +1.1

+10−10Week 1: lost to the Giants 20-28 (away)@NYG1Week 2: beat the Commanders 37-20 (home)vWAS2Week 3: lost to the Ravens 31-34 (home)vBAL3Week 4: beat the Texans 34-30 (away)@HOU4Week 5: lost to the Buccaneers 16-24 (home)vTB5Week 6: lost to the Packers 13-23 (away)@GB6Week 7: beat the Eagles 38-21 (away)@PHI7Week 8: lost to the Cardinals 30-33 (home)vARI8Week 9: beat the Colts 27-23 (away)@IND9
One bar per game this season, in week order. Bars above the line are wins and below are defeats, sized by margin. “v” is a home game and “@” an away game. Hover or tap a bar for the score. Bye weeks are left blank, so a gap in a run of form is visible rather than hidden.

49ers vs Cowboys quarterback matchup

Brock Purdy threw for 232 yards and two touchdowns at 107.4 in a 38-17 win. Dak Prescott went 21 of 34 for 335 and two scores at 114.2.

TeamQuarterbackLast gameSeason to date
49ersBrock Purdy17/25, 232 yds, 2 TD, 1 INT, 107.4 rtg163/236, 1980 yds, 17 TD, 5 INT, 109.8 rtg (8 games)
CowboysDak Prescott21/34, 335 yds, 2 TD, 0 INT, 114.2 rtg218/336, 2381 yds, 16 TD, 5 INT, 95.3 rtg (9 games)
Last game is Week 9. Season figures are 2026 to date, with games played in brackets.

49ers vs Cowboys injury report and team news

San Francisco score 3.9 touchdowns a game and convert 84.6% in the red zone, both the best in the NFL.

Dallas concede 48.3% on third down, the worst rate in the league.

San Francisco concede 3.33 yards a carry and 81 rushing yards a game, the best figures in the NFL.

The best offence in football against the most generous third down

San Francisco are 7-1 and the offence is unusually efficient: 3.9 touchdowns a game, 84.6% in the red zone and 51.7% on third down are first, first and second.

The defence is no weaker. Opponents run at 3.33 a carry for 81 yards a game, both the best marks in the league, and score 1.9 touchdowns.

Dallas can score — 3.1 touchdowns a game and 71.4% in the red zone, third — and Prescott threw for 335 last week. Stopping anyone is the trouble: 48.3% on third down and 147 rushing yards conceded.

San Francisco 49ersDallas Cowboys

Their own numbers

Touchdowns per gameSan Francisco 49ers: 3.9, 1st of 32Dallas Cowboys: 3.1, 7th of 321st3.93.17thPassing yards per gameSan Francisco 49ers: 242, 11th of 32Dallas Cowboys: 257, 6th of 3211th2422576thRushing yards per gameSan Francisco 49ers: 135, 7th of 32Dallas Cowboys: 104, 21st of 327th13510421stYards per carrySan Francisco 49ers: 4.62, 7th of 32Dallas Cowboys: 4.00, 22nd of 327th4.624.0022ndThird-down conversionSan Francisco 49ers: 51.7%, 2nd of 32Dallas Cowboys: 45.3%, 5th of 322nd51.7%45.3%5thRed-zone conversionSan Francisco 49ers: 84.6%, 1st of 32Dallas Cowboys: 71.4%, 3rd of 321st84.6%71.4%3rdSacks per gameSan Francisco 49ers: 1.9, 26th of 32Dallas Cowboys: 1.9, 24th of 3226th1.91.924thInterceptions per gameSan Francisco 49ers: 0.8, 17th of 32Dallas Cowboys: 0.4, 27th of 3217th0.80.427th
Each club’s own production, per game this season. The small grey number is the league rank out of 32.

What opponents have managed against them

Touchdowns per gameSan Francisco 49ers: 1.9, 6th of 32Dallas Cowboys: 3.0, 24th of 326th1.93.024thPassing yards per gameSan Francisco 49ers: 211, 8th of 32Dallas Cowboys: 225, 18th of 328th21122518thRushing yards per gameSan Francisco 49ers: 81, 2nd of 32Dallas Cowboys: 147, 31st of 322nd8114731stYards per carrySan Francisco 49ers: 3.33, 1st of 32Dallas Cowboys: 4.99, 30th of 321st3.334.9930thThird-down conversionSan Francisco 49ers: 40.4%, 18th of 32Dallas Cowboys: 48.3%, 32nd of 3218th40.4%48.3%32ndRed-zone conversionSan Francisco 49ers: 48.0%, 9th of 32Dallas Cowboys: 67.6%, 25th of 329th48.0%67.6%25thSacks per gameSan Francisco 49ers: 1.0, 1st of 32Dallas Cowboys: 1.6, 6th of 321st1.01.66thInterceptions per gameSan Francisco 49ers: 0.6, 12th of 32Dallas Cowboys: 0.6, 10th of 3212th0.60.610th
What each club’s opponents have managed, per game. Ranks here run the other way: first is the lowest number conceded, not the highest. The ringed dot is the better figure.

Players to watch

  • Brock Purdy (SF, QB): Rates 109.8 in an offence converting 84.6% in the red zone.
  • George Kittle (SF, TE): A primary target in the league’s most efficient offence.
  • Dak Prescott (DAL, QB): 335 yards and two touchdowns at 114.2 last week.
  • CeeDee Lamb (DAL, WR): Led Dallas receivers in the win over Indianapolis.

How to watch 49ers vs Cowboys

Kickoff is 9.25pm GMT on Sunday 15 November at AT&T Stadium, which is 4:25 PM ET. Channel 5 and 5ACTION show selected games free-to-air each Sunday, and those are not affected by the blackout. Check their listings for this week’s picks. Sky Sports has the UK coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky takes one exclusive pick from each of the two Sunday afternoon windows, and those two reach Game Pass 24 hours after the final whistle. Squawka may earn a commission if you subscribe through that link.

Detail49ers vs Cowboys
DateSunday, November 15, 2026
Kickoff9.25pm GMT Sun 15 Nov / 4:25 PM ET
VenueAT&T Stadium, Arlington, TX
TVSky Sports
Live streamNFL Game Pass (DAZN)
WeekWeek 10, 2026 NFL season

49ers vs Cowboys prediction and score projection

Our 49ers vs Cowboys prediction is San Francisco by 34-24. Dallas will score, because they always do, and 48.3% conceded on third down against this offence is not survivable.

The projected margin on this page updates through the week.

Every Week 10 game, previewed

Kickoff (GMT)GameOur predictionPreview
Fri 1:15 AMCommanders @ GiantsGiants 23-20Read
Sun 2:30 PMPatriots @ LionsLions 31-24Read
Sun 6:00 PMBills @ JetsBills 30-17Read
Sun 6:00 PMPanthers @ SaintsSaints 27-24Read
Sun 6:00 PMTexans @ BrownsTexans 26-17Read
Sun 6:00 PMJaguars @ TitansJaguars 27-13Read
Sun 6:00 PMChiefs @ FalconsChiefs 27-16Read
Sun 6:00 PMDolphins @ ColtsColts 20-16Read
Sun 6:00 PMVikings @ PackersPackers 20-13Read
Sun 9:05 PMRams @ CardinalsRams 24-16Read
Sun 9:05 PMSeahawks @ RaidersSeahawks 27-13Read
Sun 9:25 PM49ers @ Cowboys49ers 34-24You are here
Mon 1:20 AMSteelers @ BengalsBengals 27-23Read
Tue 1:15 AMChargers @ RavensRavens 23-13Read

Every fixture in the round is covered across our NFL UK hub, and the 32 club pages sit on the NFL teams hub.

49ers vs Cowboys FAQ

What time is 49ers vs Cowboys in the UK?

9.25pm GMT on Sunday 15 November at AT&T Stadium, which is 4:25 PM ET.

How can I watch 49ers vs Cowboys in the UK?

Sky Sports has the coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky holds one exclusive pick in each of the two Sunday afternoon windows, and those two reach Game Pass 24 hours after the final whistle. Channel 5 and 5ACTION carry the week’s free-to-air games, and those are not blacked out.

Which side has the best red-zone offence?

San Francisco, at 84.6% — the best conversion rate in the NFL.

Why are Dallas 4-5?

Third down. They concede 48.3%, the worst rate in the league.

18+ | Please gamble responsibly | BeGambleAware.org | Signal probabilities approximate at time of writing and subject to change