San Francisco 49ers Odds & Predictions
Squawka Signal’s projected line and win probability for every 49ers game this season, plus NFC West standings and Super Bowl odds.
49ers 2026 outlook
| Market | Squawka | |
|---|---|---|
| 49ers Super Bowl oddsFull odds | 10.7% | Signal read |
| 49ers NFC Championship oddsFull odds | 21.3% | Signal read |
| 49ers NFC West odds | 56.4% | Signal read |
Moneyline
Against the spread
Squawka Signal is a 538-lineage Elo model with a 10,000-run Monte Carlo season simulation. Model numbers are a view, not a guarantee. 18+. BeGambleAware.org. Please gamble responsibly.
NFC West standings and division odds
Division and playoff odds are the model’s, from a 10,000-run season simulation.
| Team | Record | Win NFC West | Playoffs |
|---|---|---|---|
| San Francisco 49ers | 4-0 | 56.4% | 92.4% |
 Seattle Seahawks | 3-1 | 31.5% | 80.7% |
 Los Angeles Rams | 2-2 | 12.1% | 69.0% |
 Arizona Cardinals | 1-3 | 0.0% | 0.4% |
San Francisco 49ers schedule, results and lines
Every game with the model’s win probability and projected line.
Los Angeles Rams Neutral siteFri Sep 11, 1:35 AM BST53%win prob-0.8proj lineW 27–7FinalRead preview
49ers injury report
Out long-term
| Player | Pos | Status |
|---|---|---|
| Nate Hobbs | CB | IR |
| Alfred Collins | DL | IR |
| Andrew Farmer II | DL | IR |
| Mikail Kamara | DL | IR |
| Mykel Williams | DL | IR |
| Sam Okuayinonu | DL | IR |
| C.J. West | DT | IR |
| Nick Martin | LB | IR |
| Austen Pleasants | OL | IR |
| Brett Toth | OL | IR |
| Nick Zakelj | OL | IR |
| Darrick Forrest | SAF | IR |
| Jake Tonges | TE | IR |
| Christian Kirk | WR | IR |
| De'Zhaun Stribling | WR | IR |
| Demarcus Robinson | WR | IR |
| Ricky Pearsall | WR | IR |
| Isaac Guerendo | RB | PUP |
Latest 49ers coverage
Broncos vs 49ers Prediction & Tips: Week 4Match preview · 4 days agoHow to Watch San Francisco 49ers vs Denver Broncos Live in the UK on DAZNMatch preview · 7 days agoCardinals vs 49ers Prediction & TipsMatch preview · 11 days agoHow to Watch Cardinals vs 49ers Live in the UK on DAZNMatch preview · 15 days agoDolphins vs 49ers Prediction & TipsMatch preview · 18 days agoHow to Watch Miami Dolphins vs San Francisco 49ers Live in the UK on DAZNMatch preview · 22 days agoSan Francisco 49ers roster
90 players · tap to open
Offense 45
| # | Player | Pos | Exp | College |
|---|---|---|---|---|
| 10 | Mac Jones | QB | 6 | Alabama |
| 13 | Brock Purdy | QB | 5 | Iowa State |
| 14 | Kurtis Rourke | QB | 1 | Indiana |
| 26 | Kaelon Black | RB | Indiana | |
| 31 | Isaac Guerendo | RB | 3 | Louisville |
| 29 | Jordan James | RB | 2 | Oregon |
| 23 | Christian McCaffrey | RB | 10 | Stanford |
| 35 | Sincere McCormick | RB | 3 | UTSA |
| 44 | Kyle Juszczyk | FB | 14 | Harvard |
| 11 | Brandon Aiyuk | WR | 6 | Arizona State |
| 84 | Brandin Cooks | WR | 13 | Oregon State |
| 4 | Jacob Cowing | WR | 3 | Arizona |
| 5 | Mike Evans | WR | 13 | Texas A&M |
| 81 | Wesley Grimes | WR | NC State | |
| 3 | Christian Kirk | WR | 9 | Texas A&M |
| 18 | Will Pauling | WR | Notre Dame | |
| 1 | Ricky Pearsall | WR | 3 | Florida |
| 15 | Dante Pettis | WR | 8 | Washington |
| 11 | Demarcus Robinson | WR | 11 | Florida |
| 15 | Xavier Smith | WR | 3 | Florida A&M |
| 19 | Deebo Samuel Sr. | WR | 8 | South Carolina |
| 7 | De'Zhaun Stribling | WR | Ole Miss | |
| 6 | Malik Turner | WR | 5 | Illinois |
| 17 | Jordan Watkins | WR | 2 | Ole Miss |
| 82 | Khalil Dinkins | TE | Penn State | |
| 89 | Luke Farrell | TE | 6 | Ohio State |
| 85 | George Kittle | TE | 10 | Iowa |
| 83 | Jack Stoll | TE | 6 | Nebraska |
| 88 | Jake Tonges | TE | 4 | California |
| 9 | Brayden Willis | TE | 4 | Oklahoma |
| 71 | Trent Williams | T | 17 | Oklahoma |
| 67 | Isaac Alarcon | OL | 1 | |
| 64 | Jake Brendel | OL | 9 | UCLA |
| 75 | Connor Colby | OL | 2 | Iowa |
| 69 | Enrique Cruz Jr. | OL | Kansas | |
| 76 | Vederian Lowe | OL | 5 | Illinois |
| 68 | Colton McKivitz | OL | 7 | West Virginia |
| 66 | Drake Nugent | OL | 1 | Michigan |
| 58 | Jarrett Patterson | OL | 4 | Notre Dame |
| 62 | Austen Pleasants | OL | 2 | Ohio |
| 77 | Dominick Puni | OL | 3 | Kansas |
| 61 | Foster Sarell | OL | 5 | Stanford |
| 78 | Brett Toth | OL | 7 | Army |
| 74 | Carver Willis | OL | Washington | |
| 63 | Nick Zakelj | OL | 4 | Fordham |
Defense 42
| # | Player | Pos | Exp | College |
|---|---|---|---|---|
| 65 | McKinnley Jackson | DT | 3 | Texas A&M |
| 99 | C.J. West | DT | 2 | Indiana |
| 97 | Nick Bosa | DL | 8 | Ohio State |
| 95 | Alfred Collins | DL | 2 | Texas |
| 90 | Kevin Givens | DL | 7 | Penn State |
| 93 | Gracen Halton | DL | Oklahoma | |
| 94 | Romello Height | DL | Texas Tech | |
| 50 | Andrew Farmer II | DL | 2 | Lane |
| 50 | Naquan Jones | DL | 7 | Michigan State |
| 96 | James Thompson Jr. | DL | Illinois | |
| Viliami Fehoko Jr. | DL | 2 | San Jose State | |
| 43 | Matthew Judon | DL | 10 | Grand Valley State |
| 59 | Mikail Kamara | DL | Indiana | |
| 47 | Khalid Kareem | DL | 4 | Notre Dame |
| 92 | Osa Odighizuwa | DL | 6 | UCLA |
| 59 | Ogbo Okoronkwo | DL | 9 | Oklahoma |
| 91 | Sam Okuayinonu | DL | 4 | Maryland |
| 55 | Sebastian Valdez | DL | 1 | Washington |
| 56 | Keion White | DL | 4 | Georgia Tech |
| 98 | Mykel Williams | DL | 2 | Georgia |
| 48 | Tatum Bethune | LB | 3 | Florida State |
| 53 | Jaden Dugger | LB | Louisiana | |
| 51 | Luke Gifford | LB | 8 | Nebraska |
| 41 | Jalen Graham | LB | 3 | Purdue |
| 57 | Dre Greenlaw | LB | 8 | Arkansas |
| 45 | Nick Martin | LB | 2 | Oklahoma State |
| 49 | Garret Wallow | LB | 6 | TCU |
| 54 | Fred Warner | LB | 9 | BYU |
| 40 | Brandon Codrington | CB | 3 | North Carolina Central |
| 0 | Renardo Green | CB | 3 | Florida State |
| 22 | Nate Hobbs | CB | 6 | Illinois |
| 25 | Jack Jones | CB | 5 | Arizona State |
| 28 | Ephesians Prysock | CB | Washington | |
| 20 | Upton Stout | CB | 2 | Western Kentucky |
| 27 | Ji'Ayir Brown | SAF | 4 | Penn State |
| 24 | Ashtyn Davis | SAF | 7 | California |
| 29 | Darrick Forrest | SAF | 5 | Cincinnati |
| 6 | Malik Mustapha | SAF | 3 | Wake Forest |
| 36 | Marques Sigle | SAF | 2 | Kansas State |
| 38 | Jalen Stroman | SAF | Notre Dame | |
| 2 | Deommodore Lenoir | DB | 6 | Oregon |
| 33 | Siran Neal | DB | 9 | Jacksonville State |
Special teams 3
| # | Player | Pos | Exp | College |
|---|---|---|---|---|
| 18 | Eddy Pineiro | K | 9 | Florida |
| 15 | Corliss Waitman | P | 4 | South Alabama |
| 46 | Jon Weeks | LS | 17 | Baylor |
San Francisco 49ers FAQ
What are the 49ers’ Super Bowl odds?
Squawka Signal gives the 49ers a 10.7% chance of winning Super Bowl LXI. See the full Super Bowl odds.
Can the 49ers win the NFC West?
The model makes them 56.4% to win the NFC West. That makes them the favourite, ahead of the Seattle Seahawks at 31.5%.
Will the 49ers make the playoffs?
Signal has them at 92.4% to reach the postseason, and 27.2% to take the No.1 seed in the NFC.
Who do the 49ers play next?
Week 5, away at Seattle Seahawks on Sun Oct 11, 9:25 PM BST. Signal makes the 49ers 44% with a projected line of SF +1.7.
Who is the 49ers’ starting quarterback?
Mac Jones. That is the projected starter our model rates the 49ers on, taken from last season’s attempts plus any offseason moves — not an official depth chart.
What record are the 49ers projected to finish with?
Adding up the model’s win probability for all 17 games gives an expected 11-6 (11.0 wins).
When is the 49ers’ bye week?
Week 8 of the 2026 season.
What is the 49ers’ power ranking?
Signal ranks them #5 of 32. The rating behind it is built from results and margin of victory, adjusted for opponent quality and for who is playing quarterback.
Where do the 49ers play?
San Francisco 49ers play their home games at Levi's Stadium.