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Colts vs Commanders Prediction, Picks & Odds

Indianapolis Colts vs Washington Commanders prediction, picks and odds for Week 4 of the 2026 NFL season

Our Colts vs Commanders prediction covers the first London game of 2026, and it pairs two defenses that have stopped almost nothing. Squawka Signal’s live read on this game, including where the value sits, updates on this page through the week.

The Indianapolis Colts have allowed 10 touchdowns and a 110.4 opponent passer rating in three games. The Washington Commanders have allowed 11 and a 124.4 rating, the highest figure in the league. Both are 1-2, and Tottenham Hotspur Stadium should be busy.

Week 4 · Editorial pick

Colts vs Commanders: our editor’s props

Two editorial calls to sit alongside the live Signal numbers on this page.

Colts AT Commanders

Our props

TotalOver 47.5 pointsWashington have conceded 11 touchdowns and a 124.4 opponent rating; Indianapolis have conceded 10 and 424 rushing yards. Both convert two thirds of their own red-zone trips.
★★★★☆4/5 confidence
Player propMarcus Mariota 2+ passing touchdownsMariota threw three against Seattle at a 110.0 rating and has seven scores from 47 attempts this season. Indianapolis have allowed five touchdown passes in three games.
★★★☆☆3/5 confidence

An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.

Colts vs Commanders: 2026 form so far

Neither of these defenses has held anyone. The table puts each attack against what the opposite side has actually been giving up.

Colts attack against the Commanders defense

Per gameColts offenseCommanders allow
Passing yards190.0280.3
Rushing yards103.382.0
Yards per carry3.73.8
Passer rating80.8124.4
Touchdowns2.33.7
Third-down conversion40.5%47.1%
Red-zone conversion66.7%75.0%
Sacks conceded / recorded2.01.7

Commanders attack against the Colts defense

Per gameCommanders offenseColts allow
Passing yards182.0276.0
Rushing yards132.0141.3
Yards per carry4.14.9
Passer rating98.5110.4
Touchdowns3.03.3
Third-down conversion38.1%36.4%
Red-zone conversion66.7%66.7%
Sacks conceded / recorded1.02.3

Read these as a 3-game sample rather than settled form. Rates this early move a long way on one result.

Washington’s 124.4 opponent passer rating is the number that shapes this game. Indianapolis are not far behind at 110.4, which is why the total matters more than the spread.

Colts vs Commanders quarterback matchup

Marcus Mariota has seven touchdown passes from 47 attempts. Daniel Jones has three from 98.

TeamQuarterbackLast gameSeason to date
ColtsDaniel Jones24/36, 235 yds, 1 TD, 1 INT, 82.5 rtg65/98, 611 yds, 3 TD, 3 INT, 80.8 rtg (3 games)
CommandersMarcus Mariota19/31, 183 yds, 3 TD, 0 INT, 110.0 rtg30/47, 294 yds, 4 TD, 0 INT, 109.7 rtg (2 games)
Last game is Week 3. Season figures are 2026 to date, with games played in brackets.

Colts vs Commanders injury report and team news

Alec Pierce is on injured reserve for Indianapolis, so the Colts are without the receiver who made 1,003 yards last season.

Marcus Mariota started Washington’s Week 3 win over Seattle and threw three touchdowns without an interception, his second start of the season.

This section updates as soon as the Out, Doubtful and Questionable tags land.

Where Colts vs Commanders is decided

Washington have allowed a 124.4 passer rating across three games, and they still beat Seattle 33-31. That is the shape of their season: enough points to survive whatever the defense concedes, and a 66.7% red-zone conversion rate to back it up.

Indianapolis arrive off a 19-17 win at home to Houston in which Daniel Jones threw for 235 at an 82.5 rating. They have run 83 times for 310 yards, but only 3.7 a carry, so the ground game is volume rather than efficiency.

Neutral ground removes Washington’s crowd, which matters when a defense is this porous. Even so, the Commanders have scored nine touchdowns to Indianapolis’s seven, and that margin is the case for backing them.

Players to watch

  • Daniel Jones (IND, QB): 235 yards and a touchdown against Houston at an 82.5 rating.
  • Tyler Warren (IND, TE): Nine catches from 10 targets for 55 yards in Week 3.
  • Marcus Mariota (WAS, QB): Three touchdown passes against Seattle at a 110.0 rating.
  • Terry McLaurin (WAS, WR): Six catches for 77 yards and a score in Week 3.

How to watch Colts vs Commanders

Kickoff is 9:30 AM ET on Sunday, October 4 at Tottenham Hotspur Stadium in London, which is 8:30 AM CT and 6:30 AM PT. NFL Network has the national broadcast.

DetailColts vs Commanders
DateSunday, October 4, 2026
Kickoff9:30 AM ET / 8:30 AM CT / 6:30 AM PT
VenueTottenham Hotspur Stadium, London
TVNFL Network
Live streamNFL+ / NFL Network
WeekWeek 4, 2026 NFL season

Colts vs Commanders prediction and score projection

Our Colts vs Commanders prediction is a Washington win, 27-24. The Commanders have scored more and convert more of what they reach, and neither defense looks likely to settle this.

The live win probability and the model’s projected margin update on this page through the week.

Every Week 4 game, previewed

Kickoff (ET)GameOur predictionPreview
Thu 8:15 PMSteelers @ BrownsBrowns 20-17Read
Sun 9:30 AMColts @ CommandersCommanders 27-24You are here
Sun 1:00 PMCardinals @ GiantsCardinals 24-20Read
Sun 1:00 PMCowboys @ TexansCowboys 27-24Read
Sun 1:00 PMPackers @ BuccaneersPackers 23-20Read
Sun 1:00 PMJaguars @ BengalsJaguars 24-20Read
Sun 1:00 PMRams @ EaglesRams 24-20Read
Sun 1:00 PMPatriots @ BillsBills 30-16Read
Sun 1:00 PMJets @ BearsBears 27-24Read
Sun 1:00 PMTitans @ RavensRavens 27-13Read
Sun 4:05 PMDolphins @ VikingsVikings 24-13Read
Sun 4:25 PMBroncos @ 49ers49ers 31-17Read
Sun 4:25 PMChiefs @ RaidersChiefs 27-24Read
Sun 4:25 PMChargers @ SeahawksSeahawks 27-17Read
Sun 8:20 PMLions @ PanthersLions 31-24Read
Mon 8:15 PMFalcons @ SaintsSaints 26-23Read

Every fixture in the round is covered across our NFL hub, and Signal rates every game on the NFL picks page.

Colts vs Commanders FAQ

Who is favored to win, the Colts or the Commanders?

Washington, narrowly, on neutral ground in London. Both teams are 1-2, but the Commanders have scored nine touchdowns to Indianapolis’s seven.

What time is Colts vs Commanders?

9:30 AM ET on Sunday, October 4, which is 2:30pm in London, at Tottenham Hotspur Stadium.

Is Alec Pierce playing for the Colts?

No. Pierce is on injured reserve. He made 1,003 receiving yards for Indianapolis last season.

Where is the Colts vs Commanders game being played?

Tottenham Hotspur Stadium in London, not Washington’s Northwest Stadium. It is the first of the 2026 London games.

21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change