San Francisco has not allowed a sack all season. It is the only team in the NFL that can say that, and our 49ers vs Seahawks prediction sends it to the loudest stadium in the league to defend it.
This is the game of the week. The San Francisco 49ers are 4-0 with a +58 point differential, the best in football. The Seattle Seahawks are 3-1 and have conceded 579 passing yards, fewer than anyone else.
49ers vs Seahawks: our editor’s props
Two editor’s calls on this game, alongside the live Signal numbers.
AT 
Our props
An editorial call, not a Signal model output. 19+ (18+ in AB, MB and QC). Please play responsibly.
49ers vs Seahawks: 2026 form so far
The best record in football against the best pass defence. The table measures each attack against what the opposing team has actually conceded.
49ers attack against the Seahawks defence
| Per game | 49ers offence | Seahawks allow |
|---|---|---|
| Passing yards | 251.8 | 144.8 |
| Rushing yards | 137.2 | 102.0 |
| Yards per carry | 4.8 | 3.6 |
| Passer rating | 126.2 | 72.1 |
| Touchdowns | 4.0 | 2.0 |
| Third-down conversion | 57.5% | 28.6% |
| Red-zone conversion | 84.6% | 66.7% |
| Sacks conceded / recorded | 0.0 | 2.8 |
Seahawks attack against the 49ers defence
| Per game | Seahawks offence | 49ers allow |
|---|---|---|
| Passing yards | 237.0 | 209.0 |
| Rushing yards | 110.2 | 99.8 |
| Yards per carry | 3.9 | 3.7 |
| Passer rating | 112.1 | 87.1 |
| Touchdowns | 3.2 | 1.5 |
| Third-down conversion | 31.1% | 44.1% |
| Red-zone conversion | 56.2% | 45.5% |
| Sacks conceded / recorded | 1.5 | 1.5 |
Figures are season to date, across 4 games.
Zero sacks allowed in four games and 113 pass attempts. No other team in the league is on fewer than five, and Seattle’s eleven sacks make this the matchup the game turns on.
49ers vs Seahawks quarterback matchup
San Francisco’s 126.2 team passer rating is the highest in the league, and Seattle’s 112.1 is third. This is the best quarterback matchup on the card.
| Team | Quarterback | Last game | Season to date |
|---|---|---|---|
| 49ers | Brock Purdy | 15/27, 297 yds, 4 TD, 0 INT, 133.8 rtg | 79/113, 1007 yds, 11 TD, 1 INT, 126.2 rtg (4 games) |
| Seahawks | Sam Darnold | 31/45, 379 yds, 4 TD, 2 INT, 105.7 rtg | 45/69, 560 yds, 6 TD, 3 INT, 101.1 rtg (3 games) |
49ers vs Seahawks injury report and team news
San Francisco’s receiving room has been thinned by injury, with Ricky Pearsall and Christian Kirk both on injured reserve. Mike Evans and Brandin Cooks have taken the load alongside George Kittle.
Zach Charbonnet is on injured reserve for Seattle, leaving the backfield to Emanuel Wilson and George Holani.
Seattle has conceded 579 passing yards, the fewest of any team in the NFL.
Zero sacks against eleven
Start with the protection. San Francisco has given up nothing in 113 attempts, which is why Brock Purdy has eleven touchdown passes and a 126.2 rating, both at or near the top of the league.
Seattle is the first team equipped to break it. Eleven sacks, a 72.1 opponent passer rating that only Minnesota betters, and 28.6% allowed on third down.
San Francisco has one genuine vulnerability and it is personnel. With Pearsall and Kirk on injured reserve, the receiving group leans on Mike Evans, Brandin Cooks and Kittle, which is a narrower set of answers than it has needed so far.
Players to watch
- George Kittle (SF, TE): 244 yards, and the surest hands in a depleted group.
- Christian McCaffrey (SF, RB): 218 yards behind a line yet to concede a sack.
- Jaxon Smith-Njigba (SEA, WR): 481 yards from 32 catches, third in the league.
- Cooper Kupp (SEA, WR): The second read in a passing game rating 112.1.
How to watch 49ers vs Seahawks
Kickoff is 4:25 PM ET on Sunday, October 11 at Lumen Field in Seattle. CTV’s Sunday afternoon pick varies by region, so your local listings decide whether this is the game you get. RDS carries the French-language broadcast. DAZN carries every game of the season in Canada through NFL Game Pass. Squawka may earn a commission if you subscribe through that link.
| Detail | 49ers vs Seahawks |
|---|---|
| Date | Sunday, October 11, 2026 |
| Kickoff | 4:25 PM ET / 3:25 PM CT / 1:25 PM PT |
| Venue | Lumen Field, Seattle, WA |
| TV | CTV (regional) / TSN / RDS (French) |
| Live stream | DAZN (NFL Game Pass) |
| Week | Week 5, 2026 NFL season |
49ers vs Seahawks prediction and score projection
Our 49ers vs Seahawks prediction is Seattle 24-21. This is the upset call of the week: the Seahawks have the pass defence to make San Francisco uncomfortable for the first time, and Lumen Field does the rest.
The model’s number and the live market price both update through the week.
Every Week 5 game, previewed
| Kickoff (ET) | Game | Our prediction | Preview |
|---|---|---|---|
| Thu 8:15 PM | Buccaneers @ Cowboys | Cowboys 27-20 | Read |
| Sun 9:30 AM | Eagles @ Jaguars | Jaguars 24-17 | Read |
| Sun 1:00 PM | Bears @ Packers | Bears 24-20 | Read |
| Sun 1:00 PM | Bengals @ Dolphins | Bengals 27-16 | Read |
| Sun 1:00 PM | Browns @ Jets | Browns 20-17 | Read |
| Sun 1:00 PM | Texans @ Titans | Texans 19-16 | Read |
| Sun 1:00 PM | Colts @ Steelers | Steelers 21-20 | Read |
| Sun 1:00 PM | Raiders @ Patriots | Raiders 23-20 | Read |
| Sun 1:00 PM | Vikings @ Saints | Vikings 26-17 | Read |
| Sun 1:00 PM | Giants @ Commanders | Giants 24-17 | Read |
| Sun 4:05 PM | Broncos @ Chargers | Broncos 23-17 | Read |
| Sun 4:25 PM | Lions @ Cardinals | Lions 27-20 | Read |
| Sun 4:25 PM | 49ers @ Seahawks | Seahawks 24-21 | You are here |
| Sun 8:20 PM | Ravens @ Falcons | Ravens 26-20 | Read |
| Mon 8:15 PM | Bills @ Rams | Bills 27-23 | Read |
The rest of the week is covered across our NFL hub, and Signal rates every Week 5 game the same way. Both these teams are chasing the NFC Championship odds, with the AFC Championship odds tracked alongside them through the season.
49ers vs Seahawks FAQ
San Francisco on form, at 4-0 with the best point differential in the NFL. Seattle is 3-1 and at home.
4:25 PM ET on Sunday, October 11, which is 3:25 PM CT and 1:25 PM PT, at Lumen Field.
No sacks in four games and 113 pass attempts. They are the only team in the NFL yet to allow one.
It has conceded 579 passing yards, the fewest in the league, at a 72.1 opponent rating.
19+ (18+ in AB, MB and QC) | Please play responsibly | ConnexOntario: 1-866-531-2600 (ON) | Signal probabilities approximate at time of writing and subject to change