San Francisco 49ers Odds & Predictions
Squawka Signal’s projected line and win probability for every 49ers game this season, plus NFC West standings and Super Bowl odds.
49ers 2026 outlook
| Market | Squawka | |
|---|---|---|
| 49ers Super Bowl oddsFull odds | 2.6% | Signal read |
| 49ers NFC Championship oddsFull odds | 6.3% | Signal read |
| 49ers NFC West odds | 15.7% | Signal read |
Moneyline
Against the spread
Squawka Signal is a 538-lineage Elo model with a 10,000-run Monte Carlo season simulation. Model numbers are a view, not a guarantee. 19+ (18+ in AB/MB/QC). Please play responsibly. ConnexOntario: 1-866-531-2600 (ON).
NFC West standings and division odds
Records begin after Week 1. Division and playoff odds are the model’s, from a 10,000-run season simulation.
| Team | Record | Win NFC West | Playoffs |
|---|---|---|---|
 Seattle Seahawks | – | 44.8% | 84.3% |
 Los Angeles Rams | – | 39.2% | 80.7% |
| San Francisco 49ers | – | 15.7% | 54.9% |
 Arizona Cardinals | – | 0.4% | 2.6% |
San Francisco 49ers schedule, results and lines
Every game with the model’s win probability and projected line.
49ers injury report
Latest 49ers coverage
49ers vs Rams Prediction & Picks: Week 1Match preview · TodaySan Francisco 49ers roster
82 players · tap to open
Offense 40
| # | Player | Pos | Exp | College |
|---|---|---|---|---|
| 10 | Mac Jones | QB | 6 | Alabama |
| 13 | Brock Purdy | QB | 5 | Iowa State |
| 14 | Kurtis Rourke | QB | 1 | Indiana |
| 26 | Kaelon Black | RB | Indiana | |
| 31 | Isaac Guerendo | RB | 3 | Louisville |
| 29 | Jordan James | RB | 2 | Oregon |
| 23 | Christian McCaffrey | RB | 10 | Stanford |
| 35 | Sincere McCormick | RB | 3 | UTSA |
| 44 | Kyle Juszczyk | FB | 14 | Harvard |
| 11 | Brandon Aiyuk | WR | 6 | Arizona State |
| 6 | Jacob Cowing | WR | 3 | Arizona |
| 5 | Mike Evans | WR | 13 | Texas A&M |
| 81 | Wesley Grimes | WR | NC State | |
| 86 | KhaDarel Hodge | WR | 9 | Prairie View A&M |
| 3 | Christian Kirk | WR | 9 | Texas A&M |
| 84 | Will Pauling | WR | Notre Dame | |
| 1 | Ricky Pearsall | WR | 3 | Florida |
| 5 | Demarcus Robinson | WR | 11 | Florida |
| 19 | Deebo Samuel Sr. | WR | 8 | South Carolina |
| 15 | De'Zhaun Stribling | WR | Ole Miss | |
| 17 | Jordan Watkins | WR | 2 | Ole Miss |
| 82 | Khalil Dinkins | TE | Penn State | |
| 89 | Luke Farrell | TE | 6 | Ohio State |
| 85 | George Kittle | TE | 10 | Iowa |
| 88 | Jake Tonges | TE | 4 | California |
| Brayden Willis | TE | 4 | Oklahoma | |
| 71 | Trent Williams | OT | 17 | Oklahoma |
| 76 | Vederian Lowe | T | 5 | Illinois |
| 67 | Isaac Alarcon | OL | 1 | |
| 64 | Jake Brendel | OL | 9 | UCLA |
| 75 | Connor Colby | OL | 2 | Iowa |
| 69 | Enrique Cruz Jr. | OL | Kansas | |
| 68 | Colton McKivitz | OL | 7 | West Virginia |
| 66 | Drake Nugent | OL | 1 | Michigan |
| 58 | Jarrett Patterson | OL | 4 | Notre Dame |
| 62 | Austen Pleasants | OL | 2 | Ohio |
| 77 | Dominick Puni | OL | 3 | Kansas |
| 78 | Brett Toth | OL | 7 | Army |
| 74 | Carver Willis | OL | Washington | |
| 63 | Nick Zakelj | OL | 4 | Fordham |
Defense 39
| # | Player | Pos | Exp | College |
|---|---|---|---|---|
| Vincent Anthony Jr. | DE | Duke | ||
| 95 | Alfred Collins | DT | 2 | Texas |
| 93 | Gracen Halton | DT | Oklahoma | |
| 96 | James Thompson Jr. | DT | Illinois | |
| 92 | Osa Odighizuwa | DT | 6 | UCLA |
| 99 | C.J. West | DT | 2 | Indiana |
| 97 | Nick Bosa | DL | 8 | Ohio State |
| 58 | Romello Height | DL | Texas Tech | |
| 50 | Andrew Farmer II | DL | 2 | Lane |
| 59 | Mikail Kamara | DL | Indiana | |
| 59 | Ogbo Okoronkwo | DL | 9 | Oklahoma |
| 91 | Sam Okuayinonu | DL | 4 | Maryland |
| 55 | Sebastian Valdez | DL | 1 | Washington |
| 56 | Keion White | DL | 4 | Georgia Tech |
| 98 | Mykel Williams | DL | 2 | Georgia |
| 48 | Tatum Bethune | LB | 3 | Florida State |
| 51 | Luke Gifford | LB | 8 | Nebraska |
| 41 | Jalen Graham | LB | 3 | Purdue |
| 57 | Dre Greenlaw | LB | 8 | Arkansas |
| 45 | Nick Martin | LB | 2 | Oklahoma State |
| 49 | Garret Wallow | LB | 6 | TCU |
| 54 | Fred Warner | LB | 9 | BYU |
| 53 | Jaden Dugger | OLB | Louisiana | |
| 47 | Khalid Kareem | OLB | 4 | Notre Dame |
| Brandon Codrington | CB | 3 | North Carolina Central | |
| 0 | Renardo Green | CB | 3 | Florida State |
| 22 | Nate Hobbs | CB | 6 | Illinois |
| 24 | Jack Jones | CB | 5 | Arizona State |
| 33 | Siran Neal | CB | 9 | Jacksonville State |
| 35 | Ephesians Prysock | CB | Washington | |
| 43 | Jakob Robinson | CB | 2 | BYU |
| 20 | Upton Stout | CB | 2 | Western Kentucky |
| 27 | Ji'Ayir Brown | SAF | 4 | Penn State |
| 24 | Ashtyn Davis | SAF | 7 | California |
| 6 | Malik Mustapha | SAF | 3 | Wake Forest |
| 36 | Marques Sigle | SAF | 2 | Kansas State |
| 38 | Jalen Stroman | SAF | Notre Dame | |
| 29 | Darrick Forrest | DB | 5 | Cincinnati |
| 2 | Deommodore Lenoir | DB | 6 | Oregon |
Special teams 3
| # | Player | Pos | Exp | College |
|---|---|---|---|---|
| 18 | Eddy Pineiro | K | 9 | Florida |
| 15 | Corliss Waitman | P | 4 | South Alabama |
| 46 | Jon Weeks | LS | 17 | Baylor |
San Francisco 49ers FAQ
What are the 49ers’ Super Bowl odds?
Squawka Signal gives the 49ers a 2.6% chance of winning Super Bowl LXI. See the full Super Bowl odds.
Can the 49ers win the NFC West?
The model makes them 15.7% to win the NFC West. The Seattle Seahawks are favoured at 44.8%.
Will the 49ers make the playoffs?
Signal has them at 54.9% to reach the postseason, and 6.2% to take the No.1 seed in the NFC.
Who do the 49ers play next?
Week 1, away at Los Angeles Rams on Thu Sep 10, 8:35 PM ET. Signal makes the 49ers 40% with a projected line of SF +2.7. Read our full preview.
Who is the 49ers’ starting quarterback?
Mac Jones. That is the projected starter our model rates the 49ers on, taken from last season’s attempts plus any offseason moves — not an official depth chart.
What record are the 49ers projected to finish with?
Adding up the model’s win probability for all 17 games gives an expected 9-8 (9.4 wins).
When is the 49ers’ bye week?
Week 8 of the 2026 season.
What is the 49ers’ power ranking?
Signal ranks them #12 of 32. The rating behind it is built from results and margin of victory, adjusted for opponent quality and for who is playing quarterback.
Where do the 49ers play?
San Francisco 49ers play their home games at Levi's Stadium.