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Lions vs Panthers Prediction, Picks & Odds

Detroit Lions vs Carolina Panthers prediction, picks and odds for Week 4 of the 2026 NFL season

Our Lions vs Panthers prediction closes the Sunday schedule with the two defenses that have given up the most, in opposite ways. Squawka Signal’s live read on this game, including where the value sits, updates on this page through the week.

The Detroit Lions have conceded 13 touchdowns and 898 passing yards, both league highs. The Carolina Panthers have allowed 580 rushing yards at 5.7 a carry, also a league high. Bank of America Stadium should be busy on Sunday night.

Week 4 · Editorial pick

Lions vs Panthers: our editor’s props

Two editorial calls to sit alongside the live Signal numbers on this page.

Lions AT Panthers

Our props

TotalOver 49.5 pointsDetroit have conceded 13 touchdowns and 898 passing yards; Carolina have allowed 580 rushing yards at 5.7 a carry and concede on 85.7% of red-zone trips.
★★★★☆4/5 confidence
Player propJahmyr Gibbs 90+ scrimmage yardsGibbs ran for 99 and caught seven for 65 against the Jets. Carolina have allowed 580 rushing yards at 5.7 a carry, the most in the league.
★★★★☆4/5 confidence

An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.

Lions vs Panthers: 2026 form so far

Two defenses that have been picked apart, one through the air and one on the ground. The table puts each attack against what the opposite side has actually allowed.

Lions attack against the Panthers defense

Per gameLions offensePanthers allow
Passing yards247.7172.3
Rushing yards120.7193.3
Yards per carry4.45.7
Passer rating116.179.0
Touchdowns4.03.3
Third-down conversion41.2%45.2%
Red-zone conversion78.6%85.7%
Sacks conceded / recorded2.32.0

Panthers attack against the Lions defense

Per gamePanthers offenseLions allow
Passing yards295.7299.3
Rushing yards97.0117.3
Yards per carry4.34.4
Passer rating95.6110.2
Touchdowns3.34.3
Third-down conversion36.8%56.1%
Red-zone conversion61.5%84.6%
Sacks conceded / recorded2.34.0

Read these as a 3-game sample rather than settled form. Rates this early move a long way on one result.

Detroit concede 84.6% of red-zone trips and Carolina 85.7%. Those are the two worst figures in the league, and they are the reason the total is the play rather than the spread.

Lions vs Panthers quarterback matchup

Jared Goff has not thrown an interception this season. Bryce Young has attempted more passes than all but two quarterbacks in the league.

TeamQuarterbackLast gameSeason to date
LionsJared Goff25/32, 269 yds, 2 TD, 0 INT, 122.5 rtg77/109, 802 yds, 8 TD, 0 INT, 116.1 rtg (3 games)
PanthersBryce Young26/48, 291 yds, 1 TD, 1 INT, 70.7 rtg72/121, 939 yds, 7 TD, 2 INT, 96.4 rtg (3 games)
Last game is Week 3. Season figures are 2026 to date, with games played in brackets.

Lions vs Panthers injury report and team news

Jared Goff has thrown eight touchdown passes without an interception in three games at a 116.1 rating.

Bryce Young threw 48 times for 291 yards at Cleveland and has 939 passing yards this season, more than any other quarterback.

This section updates as soon as the Out, Doubtful and Questionable tags land.

Where Lions vs Panthers is decided

Detroit have conceded 13 touchdowns and 898 passing yards in three games, and both are the highest totals in the league. They are still 2-1, because Jared Goff has thrown eight touchdown passes without an interception and the offense has scored 12 times.

Carolina’s problem is the run. Five hundred and eighty rushing yards allowed at 5.7 a carry, and Chicago put 59 points on them in Week 1. Detroit run at 4.4 a carry with Jahmyr Gibbs, who has four rushing touchdowns already.

Both defenses concede in the red zone too, at 84.6% and 85.7%, the two worst rates in the league. Neither side is likely to be stopped when they get close, which points at the total rather than the margin.

Players to watch

  • Jared Goff (DET, QB): 25 of 32 for 269 yards and two touchdowns against the Jets.
  • Jahmyr Gibbs (DET, RB): 99 rushing yards and two touchdowns plus 65 receiving in Week 3.
  • Bryce Young (CAR, QB): 291 yards from 48 attempts at Cleveland.
  • Chuba Hubbard (CAR, RB): 19 carries for 82 yards in Week 3.

How to watch Lions vs Panthers

Kickoff is 8:20 PM ET on Sunday, October 4 at Bank of America Stadium, which is 7:20 PM CT and 5:20 PM PT. NBC has the national broadcast, with streaming on Peacock.

DetailLions vs Panthers
DateSunday, October 4, 2026
Kickoff8:20 PM ET / 7:20 PM CT / 5:20 PM PT
VenueBank of America Stadium, Charlotte, NC
TVNBC/Peacock
Live streamPeacock / NFL+
WeekWeek 4, 2026 NFL season

Lions vs Panthers prediction and score projection

Our Lions vs Panthers prediction is a Detroit win, 31-24. The Lions have the better quarterback and the better running back, and Carolina cannot stop the run.

The live win probability and the model’s projected margin update on this page through the week.

Every Week 4 game, previewed

Kickoff (ET)GameOur predictionPreview
Thu 8:15 PMSteelers @ BrownsBrowns 20-17Read
Sun 9:30 AMColts @ CommandersCommanders 27-24Read
Sun 1:00 PMCardinals @ GiantsCardinals 24-20Read
Sun 1:00 PMCowboys @ TexansCowboys 27-24Read
Sun 1:00 PMPackers @ BuccaneersPackers 23-20Read
Sun 1:00 PMJaguars @ BengalsJaguars 24-20Read
Sun 1:00 PMRams @ EaglesRams 24-20Read
Sun 1:00 PMPatriots @ BillsBills 30-16Read
Sun 1:00 PMJets @ BearsBears 27-24Read
Sun 1:00 PMTitans @ RavensRavens 27-13Read
Sun 4:05 PMDolphins @ VikingsVikings 24-13Read
Sun 4:25 PMBroncos @ 49ers49ers 31-17Read
Sun 4:25 PMChiefs @ RaidersChiefs 27-24Read
Sun 4:25 PMChargers @ SeahawksSeahawks 27-17Read
Sun 8:20 PMLions @ PanthersLions 31-24You are here
Mon 8:15 PMFalcons @ SaintsSaints 26-23Read

Every fixture in the round is covered across our NFL hub, and Signal rates every game on the NFL picks page.

Lions vs Panthers FAQ

Who is favored to win, the Lions or the Panthers?

Detroit, despite playing away. The Lions are 2-1 with 12 touchdowns; Carolina are 1-2.

What time is Lions vs Panthers?

8:20 PM ET on Sunday, October 4, at Bank of America Stadium.

Why is the total so high for this game?

Detroit have conceded 13 touchdowns and Carolina 10, and the two sides concede 84.6% and 85.7% of red-zone trips, the worst rates in the league.

How did each side do in Week 3?

Detroit beat the New York Jets 31-24. Carolina lost 21-18 at Cleveland.

21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change