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Colts vs Steelers Prediction, Picks & Odds

Indianapolis Colts vs Pittsburgh Steelers prediction, picks and odds for Week 5 of the 2026 NFL season

Sixteen penalties in four games. Indianapolis are the most disciplined team in the NFL by a clear margin, and our Colts vs Steelers prediction asks whether that is worth more than Pittsburgh’s home field.

Both sides are 2-2 with negative point differentials — the Indianapolis Colts by two points, the Pittsburgh Steelers by ten. Indianapolis convert 75% of their red-zone trips despite a 73.9 passer rating, which is an unusual way to score 102 points.

Week 5 · Editorial pick

Colts vs Steelers: our editor’s props

Two editor’s calls on this game, alongside the live Signal numbers.

Colts AT Steelers

Our props

Player propJonathan Taylor 75+ rushing yardsTaylor has 353 rushing yards, joint fifth in the NFL. Pittsburgh concede 4.34 a carry and 451 rushing yards, and Indianapolis lean on him in close games.
★★★☆☆3/5 confidence
TotalUnder 43.5 pointsPittsburgh convert 32% on third down and have conceded 13 sacks, second-most in the league. Indianapolis rate 73.9 through the air. Neither offense sustains drives easily.
★★☆☆☆2/5 confidence

An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.

Colts vs Steelers: 2026 form so far

Two 2-2 teams separated by eight points of differential. The table measures each attack against what the opposite defense has given up.

Colts attack against the Steelers defense

Per gameColts offenseSteelers allow
Passing yards174.8209.5
Rushing yards109.5112.8
Yards per carry3.94.3
Passer rating73.992.0
Touchdowns2.52.2
Third-down conversion37.7%34.8%
Red-zone conversion75.0%60.0%
Sacks conceded / recorded2.02.5

Steelers attack against the Colts defense

Per gameSteelers offenseColts allow
Passing yards223.0261.2
Rushing yards94.8131.0
Yards per carry4.44.8
Passer rating80.698.4
Touchdowns2.02.8
Third-down conversion32.0%29.2%
Red-zone conversion44.4%57.1%
Sacks conceded / recorded3.22.2

Figures are season to date, across 4 games.

Indianapolis have taken 16 penalties for 105 yards, the fewest of any team in the NFL. In a game this evenly matched, free yardage is the kind of edge that decides it.

Colts vs Steelers quarterback matchup

Pittsburgh rate 80.6 through the air against Indianapolis’s 73.9, and both lines have struggled: the Steelers have conceded 13 sacks, the Colts eight.

TeamQuarterbackLast gameSeason to date
ColtsDaniel Jones24/36, 235 yds, 1 TD, 1 INT, 82.5 rtg84/132, 754 yds, 3 TD, 4 INT, 73.9 rtg (4 games)
SteelersAaron Rodgers19/34, 292 yds, 3 TD, 1 INT, 101.6 rtg88/153, 999 yds, 7 TD, 4 INT, 81.6 rtg (4 games)
Last game is Week 3. Season figures are 2026 to date, with games played in brackets.

Colts vs Steelers injury report and team news

Alec Pierce is on injured reserve for Indianapolis, so the Colts remain without the receiver who made 1,003 yards last season.

T.J. Watt has four sacks for Pittsburgh, joint third in the league.

Jaylen Warren has 309 rushing yards at 4.41 a carry, the most productive part of the Pittsburgh offense.

Discipline against home field

Indianapolis do the small things well. Sixteen penalties for 105 yards is the lowest count in football, they convert 75% in the red zone, and they hold opponents to 29.2% on third down. None of that is glamorous and all of it travels.

What they cannot do is throw. A 73.9 passer rating is among the lowest in the league, and 699 passing yards in four games means Jonathan Taylor carries the offense. His 353 rushing yards are joint fifth in the NFL.

Pittsburgh’s problem is protection. Thirteen sacks conceded is second only to Tampa Bay, and against a Colts front with nine of their own that is the pressure point. Aaron Rodgers has seven touchdown passes, but he has not had much time to throw them.

Players to watch

  • Jonathan Taylor (IND, RB): 353 rushing yards, joint fifth in the NFL, against a defense conceding 4.34 a carry.
  • Tyler Warren (IND, TE): A central target in a passing game that has produced 699 yards.
  • Jaylen Warren (PIT, RB): 309 rushing yards at 4.41 a carry for Pittsburgh.
  • DK Metcalf (PIT, WR): The downfield threat in an offense rating 80.6 through the air.

How to watch Colts vs Steelers

Kickoff is 1:00 PM ET on Sunday, October 11 at Acrisure Stadium, which is 12:00 PM CT and 10:00 AM PT. CBS has the regional broadcast.

DetailColts vs Steelers
DateSunday, October 11, 2026
Kickoff1:00 PM ET / 12:00 PM CT / 10:00 AM PT
VenueAcrisure Stadium, Pittsburgh, PA
TVCBS
Live streamNFL+ / Paramount+
WeekWeek 5, 2026 NFL season

Colts vs Steelers prediction and score projection

Pittsburgh win 21-20. Home field decides a game this close, though Indianapolis’s discipline makes it the sort of afternoon where one flag swings it.

Our projected margin for this game moves alongside the live market price.

Every Week 5 game, previewed

Kickoff (ET)GameOur predictionPreview
Thu 8:15 PMBuccaneers @ CowboysCowboys 27-20Read
Sun 9:30 AMEagles @ JaguarsJaguars 24-17Read
Sun 1:00 PMBears @ PackersBears 24-20Read
Sun 1:00 PMBengals @ DolphinsBengals 27-16Read
Sun 1:00 PMBrowns @ JetsBrowns 20-17Read
Sun 1:00 PMTexans @ TitansTexans 19-16Read
Sun 1:00 PMColts @ SteelersSteelers 21-20You are here
Sun 1:00 PMRaiders @ PatriotsRaiders 23-20Read
Sun 1:00 PMVikings @ SaintsVikings 26-17Read
Sun 1:00 PMGiants @ CommandersGiants 24-17Read
Sun 4:05 PMBroncos @ ChargersBroncos 23-17Read
Sun 4:25 PMLions @ CardinalsLions 27-20Read
Sun 4:25 PM49ers @ SeahawksSeahawks 24-21Read
Sun 8:20 PMRavens @ FalconsRavens 26-20Read
Mon 8:15 PMBills @ RamsBills 27-23Read

You can find our pick record alongside our NFL hub. The outright markets are priced in the AFC board. We price the player markets in prop markets for this game.

Colts vs Steelers FAQ

Who is favored, the Colts or the Steelers?

Pittsburgh, at home, in a game between two 2-2 teams. The Steelers are -10 on differential, the Colts -2.

What time is Colts vs Steelers?

1:00 PM ET on Sunday, October 11, at Acrisure Stadium.

Which team takes the fewest penalties?

Indianapolis, with 16 for 105 yards in four games, the lowest count in the NFL.

How many sacks have Pittsburgh conceded?

Thirteen, second-most in the league behind Tampa Bay.

21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change