San Francisco lead the NFL in passer rating, third-down rate, red-zone conversion and fewest sacks conceded. Our 49ers vs Falcons prediction struggles to find the flaw.
The Atlanta Falcons are 2-4 but run for 5.07 a carry, third-best in the league. The San Francisco 49ers are +67, the best differential in football.
49ers vs Falcons: our editor’s props
Two editorial selections to sit with the live Signal read below.
AT 
Our props
An editorial call, not a Signal model output. 18+ | BeGambleAware.org
49ers vs Falcons: 2026 form so far
An unbeaten team against one that runs it as well as anybody. The table sets each attack against what the opposite defence has allowed.
49ers attack against the Falcons defence
| Per game | 49ers offence | Falcons allow |
|---|---|---|
| Passing yards | 238.5 | 252.0 |
| Rushing yards | 128.2 | 83.2 |
| Yards per carry | 4.6 | 3.6 |
| Passer rating | 118.1 | 95.1 |
| Touchdowns | 3.8 | 3.0 |
| Third-down conversion | 51.5% | 42.7% |
| Red-zone conversion | 85.0% | 64.0% |
| Sacks conceded / recorded | 0.8 | 2.5 |
Falcons attack against the 49ers defence
| Per game | Falcons offence | 49ers allow |
|---|---|---|
| Passing yards | 194.8 | 209.8 |
| Rushing yards | 149.5 | 90.2 |
| Yards per carry | 5.1 | 3.6 |
| Passer rating | 81.6 | 88.4 |
| Touchdowns | 2.7 | 1.7 |
| Third-down conversion | 38.9% | 38.6% |
| Red-zone conversion | 75.0% | 50.0% |
| Sacks conceded / recorded | 2.5 | 2.5 |
San Francisco have conceded five sacks in six games, fewer than any team in the NFL. Atlanta have given up 15.
49ers vs Falcons quarterback matchup
Brock Purdy has 14 touchdown passes to two interceptions at 118.1, the best team rating in football. Michael Penix Jr. has six to one at 106.0 from four starts.
| Team | Quarterback | Last game | Season to date |
|---|---|---|---|
| 49ers | Brock Purdy | 21/29, 264 yds, 1 TD, 0 INT, 111.9 rtg | 119/171, 1460 yds, 14 TD, 2 INT, 118.1 rtg (6 games) |
| Falcons | Michael Penix Jr. | 19/33, 225 yds, 3 TD, 0 INT, 108.8 rtg | 71/110, 944 yds, 6 TD, 1 INT, 106.0 rtg (4 games) |
49ers vs Falcons injury report and team news
San Francisco are 6-0 with a +67 point differential, the best in the NFL.
San Francisco have conceded five sacks in six games, the fewest of any team.
Atlanta have run for 897 yards at 5.07 a carry, the third-highest average in the league.
Four league-leading numbers, one team
A 118.1 passer rating, 51.5% on third down, 85.0% in the red zone and five sacks conceded. San Francisco lead the NFL in all four.
They also have 23 touchdowns, level with Buffalo for the most in football.
Atlanta’s route in is the ground, against a 49ers front giving up 3.61 a carry. If that does not hold, nothing else here will.
Players to watch
- Brock Purdy (SF, QB): Fourteen touchdown passes to two interceptions at 118.1.
- Christian McCaffrey (SF, RB): Runs behind a line that has conceded five sacks all season.
- Bijan Robinson (ATL, RB): Fronts a ground game averaging 5.07 a carry.
- Drake London (ATL, WR): The first read in an attack converting 75.0% in the red zone.
How to watch 49ers vs Falcons
Kickoff is 5pm GMT on Sunday 25 October at Mercedes-Benz Stadium, which is 1:00 PM ET. Channel 5 and 5ACTION show selected games free-to-air each Sunday, and those are not affected by the blackout. Check their listings for this week’s picks. Sky Sports has the UK coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky takes one exclusive pick from each of the two Sunday afternoon windows, and those two reach Game Pass 24 hours after the final whistle. Squawka may earn a commission if you subscribe through that link.
| Detail | 49ers vs Falcons |
|---|---|
| Date | Sunday, October 25, 2026 |
| Kickoff | 5.00pm GMT Sun 25 Oct / 1:00 PM ET |
| Venue | Mercedes-Benz Stadium, Atlanta, GA |
| TV | Sky Sports |
| Live stream | NFL Game Pass (DAZN) |
| Week | Week 7, 2026 NFL season |
49ers vs Falcons prediction and score projection
Our 49ers vs Falcons prediction is San Francisco by 30-20. Atlanta can run it, and will, but the 49ers have lost nothing yet.
Our projected margin updates on this page as the week’s team news lands.
Every Week 7 game, previewed
| Kickoff (BST) | Game | Our prediction | Preview |
|---|---|---|---|
| Fri 1:15 AM | Patriots @ Bears | Patriots 24-21 | Read |
| Sun 2:30 PM | Steelers @ Saints | Steelers 27-20 | Read |
| Sun 6:00 PM | Bengals @ Ravens | Ravens 27-23 | Read |
| Sun 6:00 PM | Browns @ Titans | Browns 20-16 | Read |
| Sun 6:00 PM | Colts @ Vikings | Vikings 27-13 | Read |
| Sun 6:00 PM | Dolphins @ Jets | Jets 20-16 | Read |
| Sun 6:00 PM | Giants @ Texans | Texans 23-17 | Read |
| Sun 6:00 PM | 49ers @ Falcons | 49ers 30-20 | You are here |
| Sun 6:00 PM | Buccaneers @ Panthers | Panthers 24-20 | Read |
| Sun 9:05 PM | Broncos @ Cardinals | Broncos 26-17 | Read |
| Sun 9:25 PM | Packers @ Lions | Lions 27-24 | Read |
| Sun 9:25 PM | Rams @ Raiders | Rams 27-23 | Read |
| Mon 1:20 AM | Chiefs @ Seahawks | Chiefs 24-23 | Read |
| Tue 1:15 AM | Cowboys @ Eagles | Eagles 23-20 | Read |
Every fixture in the round is covered across our NFL UK hub, and the 32 club pages sit on the NFL teams hub.
49ers vs Falcons FAQ
5pm GMT on Sunday 25 October at Mercedes-Benz Stadium, which is 1:00 PM ET.
Sky Sports has the coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky holds one exclusive pick in each of the two Sunday afternoon windows, and those two reach Game Pass 24 hours after the final whistle. Channel 5 and 5ACTION carry the week’s free-to-air games, and those are not blacked out.
They lead the NFL in passer rating, third-down rate, red-zone conversion and fewest sacks conceded.
They run for 5.07 a carry, third in the league, but San Francisco concede 3.61.
18+ | Please gamble responsibly | BeGambleAware.org | Signal probabilities approximate at time of writing and subject to change