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Squawka / NFL News / Patriots vs Bills Prediction & Tips: Week 4

Patriots vs Bills Prediction & Tips: Week 4

New England Patriots vs Buffalo Bills prediction, picks and odds for Week 4 of the 2026 NFL season

Our Patriots vs Bills prediction is this week’s free-to-air pick on 5ACTION, and it is a hard watch for New England. Squawka Signal’s live read updates on this page through the week.

The New England Patriots have thrown one touchdown and six interceptions in three games. The Buffalo Bills have scored 13 touchdowns and run for 465 yards at 5.2 a carry. Highmark Stadium is a difficult place to arrive in this state.

Week 4 · Editorial pick

Patriots vs Bills: our editor’s props

Two editorial calls to sit alongside the live Signal numbers on this page.

Patriots AT Bills

Our props

SpreadBuffalo to win by 7 or moreBuffalo have 13 touchdowns to New England’s three and convert 54.5% on third down against the Patriots’ 32.5%.
★★★★☆4/5 confidence
Player propJames Cook III 90+ rushing yardsCook ran 24 times for 154 against the Chargers. New England have allowed 325 rushing yards at 4.3 a carry.
★★★☆☆3/5 confidence

An editorial call, not a Signal model output. 18+ | BeGambleAware.org

Patriots vs Bills: 2026 form so far

A 3-0 team against a quarterback in freefall. The table sets each attack against what the opposite defence has actually allowed.

Patriots attack against the Bills defence

Per gamePatriots offenceBills allow
Passing yards197.7254.3
Rushing yards109.3107.0
Yards per carry3.94.0
Passer rating60.8105.4
Touchdowns1.03.0
Third-down conversion32.5%40.5%
Red-zone conversion16.7%61.5%
Sacks conceded / recorded3.03.0

Bills attack against the Patriots defence

Per gameBills offencePatriots allow
Passing yards246.7170.0
Rushing yards155.0108.3
Yards per carry5.24.3
Passer rating104.185.8
Touchdowns4.32.0
Third-down conversion54.5%34.3%
Red-zone conversion75.0%62.5%
Sacks conceded / recorded2.72.3

Read these as a 3-game sample rather than settled form. Rates this early move a long way on one result.

New England convert 16.7% of red-zone trips and Buffalo 75%. That is the fixture in one comparison.

Patriots vs Bills quarterback matchup

Both quarterbacks had a poor Week 3. Only one of them has thrown six interceptions across the season.

TeamQuarterbackLast gameSeason to date
PatriotsDrake Maye14/25, 199 yds, 0 TD, 2 INT, 48.6 rtg51/80, 585 yds, 1 TD, 6 INT, 58.6 rtg (3 games)
Tommy DeVito3/5, 30 yds, 0 TD, 0 INT, 77.1 rtg3/5, 30 yds, 0 TD, 0 INT, 77.1 rtg (1 game)
BillsJosh Allen16/26, 204 yds, 0 TD, 2 INT, 54.0 rtg56/86, 786 yds, 5 TD, 2 INT, 104.1 rtg (3 games)
Last game is Week 3. Season figures are 2026 to date, with games played in brackets.

Patriots vs Bills injury report and team news

Drake Maye threw two interceptions at Jacksonville and gave up five snaps to Tommy DeVito, the first time New England have split the throws this season.

A.J. Brown is on injured reserve for New England, a year after making 1,003 receiving yards for Philadelphia.

Harold Landry III remains on the physically unable to perform list after recording eight sacks last season.

Where Patriots vs Bills is decided

Drake Maye has one touchdown pass and six interceptions at a 58.6 rating. Last season he threw 31 touchdowns to eight at 113.5. That is a collapse rather than a slow start.

Buffalo are not flawless. Josh Allen managed a 54.0 rating against the Chargers and the Bills turned it over five times, then won by eight anyway.

For anyone watching free on 5ACTION, the draw is Allen rather than the contest. He has six rushing touchdowns already, so even his poor days produce points.

Players to watch

  • Drake Maye (NE, QB): 199 yards and two interceptions at Jacksonville.
  • Mack Hollins (NE, WR): Six catches for 87 yards in Week 3.
  • Josh Allen (BUF, QB): Two rushing touchdowns against the Chargers.
  • James Cook III (BUF, RB): 154 rushing yards at 6.4 a carry in Week 3.

How to watch Patriots vs Bills

Kickoff is 6.00pm BST on Sunday 4 October at Highmark Stadium, which is 1:00 PM ET. 5ACTION has it free to air from 5.30pm, and it also streams on Channel 5 Sport’s YouTube channel. Sky Sports has the UK coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky takes one exclusive pick from each of the Sunday 6pm and 9pm windows, and those two reach Game Pass 24 hours after the final whistle. Squawka may earn a commission if you subscribe through that link.

DetailPatriots vs Bills
DateSunday, October 4, 2026
Kickoff6.00pm BST / 1:00 PM ET, Sunday 4 October
VenueHighmark Stadium, Orchard Park, NY
TV5ACTION
Live streamNFL Game Pass (DAZN)
WeekWeek 4, 2026 NFL season

Patriots vs Bills prediction and score projection

Our Patriots vs Bills prediction is a Buffalo win, 30-16. The Bills have been sloppy and remain unbeaten; New England have three touchdowns in three weeks.

The live win probability and the model’s projected margin update on this page through the week.

Every Week 4 game, previewed

Kickoff (BST)GameOur predictionPreview
Fri 1:15 AMSteelers @ BrownsBrowns 20-17Read
Sun 2:30 PMColts @ CommandersCommanders 27-24Read
Sun 6:00 PMCardinals @ GiantsCardinals 24-20Read
Sun 6:00 PMCowboys @ TexansCowboys 27-24Read
Sun 6:00 PMPackers @ BuccaneersPackers 23-20Read
Sun 6:00 PMJaguars @ BengalsJaguars 24-20Read
Sun 6:00 PMRams @ EaglesRams 24-20Read
Sun 6:00 PMPatriots @ BillsBills 30-16You are here
Sun 6:00 PMJets @ BearsBears 27-24Read
Sun 6:00 PMTitans @ RavensRavens 27-13Read
Sun 9:05 PMDolphins @ VikingsVikings 24-13Read
Sun 9:25 PMBroncos @ 49ers49ers 31-17Read
Sun 9:25 PMChiefs @ RaidersChiefs 27-24Read
Sun 9:25 PMChargers @ SeahawksSeahawks 27-17Read
Mon 1:20 AMLions @ PanthersLions 31-24Read
Tue 1:15 AMFalcons @ SaintsSaints 26-23Read

Every fixture in the round is covered across our NFL UK hub, and the 32 club pages sit on the NFL teams hub.

Patriots vs Bills FAQ

Is Patriots vs Bills on free-to-air TV in the UK?

Yes. 5ACTION has it from 5.30pm ahead of a 6.00pm BST kickoff, and it also streams free on Channel 5 Sport’s YouTube channel. Sky Sports has the coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky holds one exclusive pick in each of the Sunday 6pm and 9pm windows, and those two reach Game Pass 24 hours after the final whistle. Channel 5 and 5ACTION carry the week’s free-to-air games, and those are not blacked out.

What time is Patriots vs Bills in the UK?

6.00pm BST on Sunday 4 October at Highmark Stadium, which is 1:00 PM ET.

Is this game blacked out on Game Pass?

No. 5ACTION games are not affected by the blackout, which applies only to Sky’s two Sunday exclusive picks.

Is A.J. Brown playing for New England?

No. Brown is on injured reserve. He made 1,003 receiving yards for Philadelphia last season before joining the Patriots.

18+ | Please gamble responsibly | BeGambleAware.org | Signal probabilities approximate at time of writing and subject to change