Arizona has conceded 21 touchdowns in five games, more than any team in the NFL, and traded Marvin Harrison Jr. to Houston on Sunday. Our Cardinals vs Rams prediction finds the Cardinals at their lowest point of the season.
The Los Angeles Rams are 2-3 but have thrown for 1,538 yards, more than any team in the league. The Arizona Cardinals are 1-4 with a -54 point differential, the worst figure among the 28 teams playing this week.
Cardinals vs Rams: our editor’s props
Two calls from our editor, to read next to Signal’s live numbers.
AT 
Our props
An editorial call, not a Signal model output. 19+ (18+ in AB, MB and QC). Please play responsibly.
Cardinals vs Rams: 2026 form so far
The league’s busiest passing game against the league’s worst pass defence. The table pairs every attacking number with the defensive number sitting opposite it.
Cardinals attack against the Rams defence
| Per game | Cardinals offence | Rams allow |
|---|---|---|
| Passing yards | 209.6 | 156.8 |
| Rushing yards | 91.6 | 128.4 |
| Yards per carry | 3.8 | 4.6 |
| Passer rating | 85.4 | 78.1 |
| Touchdowns | 2.4 | 2.6 |
| Third-down conversion | 40.5% | 32.8% |
| Red-zone conversion | 61.1% | 64.7% |
| Sacks conceded / recorded | 2.4 | 1.6 |
Rams attack against the Cardinals defence
| Per game | Rams offence | Cardinals allow |
|---|---|---|
| Passing yards | 307.6 | 236.8 |
| Rushing yards | 116.8 | 126.6 |
| Yards per carry | 4.6 | 4.4 |
| Passer rating | 88.2 | 117.3 |
| Touchdowns | 3.0 | 4.2 |
| Third-down conversion | 44.6% | 42.1% |
| Red-zone conversion | 65.0% | 76.5% |
| Sacks conceded / recorded | 1.4 | 2.2 |
Figures are season to date, across 5 games.
A 117.3 opponent passer rating is the worst figure in football, and it belongs to the team that just traded away its best-known receiver.
Cardinals vs Rams quarterback matchup
Los Angeles has thrown for 1,538 yards, the most in the NFL. Arizona cannot stop any of it, conceding 14 touchdown passes.
| Team | Quarterback | Last game | Season to date |
|---|---|---|---|
| Cardinals | Jacoby Brissett | 38/52, 280 yds, 2 TD, 0 INT, 98.2 rtg | 103/152, 818 yds, 6 TD, 4 INT, 83.2 rtg (4 games) |
| Rams | Matthew Stafford | 30/55, 390 yds, 2 TD, 2 INT, 74.1 rtg | 99/162, 1189 yds, 6 TD, 6 INT, 80.5 rtg (4 games) |
Cardinals vs Rams injury report and team news
Marvin Harrison Jr. was traded to Houston on 11 October and is no longer on the Arizona roster.
Los Angeles has thrown for 1,538 yards, more than any team in the NFL.
Arizona has conceded 21 touchdowns in five games, more than any other team.
The worst pass defence in football
A 117.3 opponent passer rating, 14 touchdown passes conceded and 76.5% of red-zone trips finished against them. Arizona has conceded 21 touchdowns in all.
The Rams are the wrong opponent. Their 1,538 passing yards lead the league and Davante Adams has 441 of them, with Puka Nacua on 337 behind him.
Arizona lost Marvin Harrison Jr. on Sunday, which removes the best-known attacking player from a team that has been outscored by 54. Trey McBride’s 308 receiving yards now lead the Cardinals.
Players to watch
- Davante Adams (LA, WR): 441 receiving yards, sixth in the league.
- Kyren Williams (LA, RB): 343 on the ground behind the NFL’s busiest passing game.
- Trey McBride (ARI, TE): 308 receiving yards, now the leading Arizona target.
- Jeremiyah Love (ARI, RB): 245 rushing yards for a team outscored by 54.
How to watch Cardinals vs Rams in Canada
Kickoff is 4:05 PM ET on Sunday, October 18 at SoFi Stadium in Inglewood. CTV carries one Sunday afternoon game per region and the selection is local, so confirm it in your own listings. The French-language broadcast is on RDS. DAZN carries every game of the season in Canada through NFL Game Pass. Squawka may earn a commission if you subscribe through that link.
| Detail | Cardinals vs Rams |
|---|---|
| Date | Sunday, October 18, 2026 |
| Kickoff | 4:05 PM ET / 3:05 PM CT / 1:05 PM PT |
| Venue | SoFi Stadium, Inglewood, CA |
| TV | CTV (regional) / TSN / RDS (French) |
| Live stream | DAZN (NFL Game Pass) |
| Week | Week 6, 2026 NFL season |
Cardinals vs Rams prediction and score projection
Our Cardinals vs Rams prediction is Los Angeles by 30-20. The Rams throw more than anyone, Arizona cannot stop it, and the Cardinals are a weaker team this week than last.
Signal’s live read on this game updates through the week.
Every Week 6 game, previewed
| Kickoff (ET) | Game | Our prediction | Preview |
|---|---|---|---|
| Thu 8:15 PM | Seahawks @ Broncos | Seahawks 24-20 | Read |
| Sun 9:30 AM | Texans @ Jaguars | Jaguars 27-17 | Read |
| Sun 1:00 PM | Ravens @ Browns | Ravens 27-16 | Read |
| Sun 1:00 PM | Panthers @ Eagles | Panthers 24-20 | Read |
| Sun 1:00 PM | Bears @ Falcons | Bears 23-20 | Read |
| Sun 1:00 PM | Saints @ Giants | Giants 26-20 | Read |
| Sun 1:00 PM | Jets @ Patriots | Patriots 24-17 | Read |
| Sun 1:00 PM | Steelers @ Buccaneers | Steelers 23-17 | Read |
| Sun 1:00 PM | Titans @ Colts | Colts 23-13 | Read |
| Sun 4:05 PM | Cardinals @ Rams | Rams 30-20 | You are here |
| Sun 4:25 PM | Bills @ Raiders | Bills 30-27 | Read |
| Sun 4:25 PM | Chargers @ Chiefs | Chiefs 31-13 | Read |
| Sun 8:20 PM | Cowboys @ Packers | Packers 27-24 | Read |
| Mon 8:15 PM | Commanders @ 49ers | 49ers 31-17 | Read |
Our NFL hub carries the full card, and Signal rates every Week 6 game on the same model. Both these teams are chasing the NFC Championship odds, with the AFC Championship odds tracked alongside them through the season.
Cardinals vs Rams FAQ
Los Angeles, comfortably. The Rams are 2-3 at home; Arizona is 1-4 at -54.
4:05 PM ET on Sunday, October 18, which is 3:05 PM CT and 1:05 PM PT, at SoFi Stadium.
CTV’s Sunday afternoon game is a regional pick, so check your local listings. RDS has the French call. DAZN carries every game of the season in Canada through NFL Game Pass.
Yes, traded to Houston on 11 October.
19+ (18+ in AB, MB and QC) | Please play responsibly | ConnexOntario: 1-866-531-2600 (ON) | Signal probabilities approximate at time of writing and subject to change