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Squawka / NFL News / Cardinals vs Rams Prediction & Tips: Week 6

Cardinals vs Rams Prediction & Tips: Week 6

Arizona Cardinals vs Los Angeles Rams prediction, picks and odds for Week 6 of the 2026 NFL season

Arizona have conceded 21 touchdowns in five games, more than any team in the NFL, and traded Marvin Harrison Jr. to Houston on Sunday. Our Cardinals vs Rams prediction finds them at their lowest point of the season.

The Los Angeles Rams are 2-3 but have thrown for 1,538 yards, more than any team in the league. The Arizona Cardinals are 1-4 at -54.

Week 6 · Editorial pick

Cardinals vs Rams: our editor’s props

Two calls from our editor, to read next to Signal’s live numbers.

Cardinals AT Rams

Our props

TotalOver 46.5 pointsArizona concede a 117.3 opponent passer rating and 76.5% of red-zone trips, both among the worst in the league. The Rams lead the NFL in passing yards.
★★★☆☆3/5 confidence
Player propDavante Adams 75+ receiving yardsAdams has 441 receiving yards, sixth in the NFL. Arizona concede a 117.3 opponent passer rating, the worst mark in the league, and have allowed 21 touchdowns.
★★★☆☆3/5 confidence

An editorial call, not a Signal model output. 18+ | BeGambleAware.org

Cardinals vs Rams: 2026 form so far

The league’s busiest passing game against the league’s worst pass defence. The table pairs every attacking number with the defensive number opposite it.

Cardinals attack against the Rams defence

Per gameCardinals offenceRams allow
Passing yards209.6156.8
Rushing yards91.6128.4
Yards per carry3.84.6
Passer rating85.478.1
Touchdowns2.42.6
Third-down conversion40.5%32.8%
Red-zone conversion61.1%64.7%
Sacks conceded / recorded2.41.6

Rams attack against the Cardinals defence

Per gameRams offenceCardinals allow
Passing yards307.6236.8
Rushing yards116.8126.6
Yards per carry4.64.4
Passer rating88.2117.3
Touchdowns3.04.2
Third-down conversion44.6%42.1%
Red-zone conversion65.0%76.5%
Sacks conceded / recorded1.42.2

Figures are season to date, across 5 games.

A 117.3 opponent passer rating is the worst figure in football, and it belongs to the team that just traded away its best-known receiver.

Cardinals vs Rams quarterback matchup

Los Angeles have thrown for 1,538 yards, the most in the NFL. Arizona cannot stop any of it.

TeamQuarterbackLast gameSeason to date
CardinalsJacoby Brissett38/52, 280 yds, 2 TD, 0 INT, 98.2 rtg103/152, 818 yds, 6 TD, 4 INT, 83.2 rtg (4 games)
RamsMatthew Stafford30/55, 390 yds, 2 TD, 2 INT, 74.1 rtg99/162, 1189 yds, 6 TD, 6 INT, 80.5 rtg (4 games)
Last game is Week 3. Season figures are 2026 to date, with games played in brackets.

Cardinals vs Rams injury report and team news

Marvin Harrison Jr. was traded to Houston on 11 October and is no longer on the Arizona roster.

Los Angeles have thrown for 1,538 yards, more than any team in the NFL.

Arizona have conceded 21 touchdowns in five games, more than any other team.

The worst pass defence in football

A 117.3 opponent passer rating, 14 touchdown passes conceded and 76.5% of red-zone trips finished against them.

The Rams are the wrong opponent. Davante Adams has 441 receiving yards and Puka Nacua 337 behind him.

Arizona lost Harrison on Sunday, which removes their best-known attacking player. Trey McBride’s 308 receiving yards now lead the team.

Players to watch

  • Davante Adams (LA, WR): 441 receiving yards, sixth in the NFL.
  • Kyren Williams (LA, RB): 343 rushing yards behind the league’s busiest passing game.
  • Trey McBride (ARI, TE): 308 receiving yards, now Arizona’s leading target.
  • Jeremiyah Love (ARI, RB): 245 rushing yards for a team outscored by 54.

How to watch Cardinals vs Rams

Kickoff is 9.05pm BST on Sunday 18 October at SoFi Stadium, which is 4:05 PM ET. Channel 5 and 5ACTION show selected games free-to-air each Sunday, and those are not affected by the blackout. Check their listings for this week’s picks. Sky Sports has the UK coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky takes one exclusive pick from each of the Sunday 6pm and 9pm windows, and those two reach Game Pass 24 hours after the final whistle. Squawka may earn a commission if you subscribe through that link.

DetailCardinals vs Rams
DateSunday, October 18, 2026
Kickoff9.05pm BST Sun 18 Oct / 4:05 PM ET
VenueSoFi Stadium, Inglewood, CA
TVSky Sports
Live streamNFL Game Pass (DAZN)
WeekWeek 6, 2026 NFL season

Cardinals vs Rams prediction and score projection

Our Cardinals vs Rams prediction is Los Angeles by 30-20. The Rams throw more than anyone and Arizona cannot stop it.

The live line and our projected margin both update through the week.

Every Week 6 game, previewed

Kickoff (BST)GameOur predictionPreview
Fri 1:15 AMSeahawks @ BroncosSeahawks 24-20Read
Sun 2:30 PMTexans @ JaguarsJaguars 27-17Read
Sun 6:00 PMRavens @ BrownsRavens 27-16Read
Sun 6:00 PMPanthers @ EaglesPanthers 24-20Read
Sun 6:00 PMBears @ FalconsBears 23-20Read
Sun 6:00 PMSaints @ GiantsGiants 26-20Read
Sun 6:00 PMJets @ PatriotsPatriots 24-17Read
Sun 6:00 PMSteelers @ BuccaneersSteelers 23-17Read
Sun 6:00 PMTitans @ ColtsColts 23-13Read
Sun 9:05 PMCardinals @ RamsRams 30-20You are here
Sun 9:25 PMBills @ RaidersBills 30-27Read
Sun 9:25 PMChargers @ ChiefsChiefs 31-13Read
Mon 1:20 AMCowboys @ PackersPackers 27-24Read
Tue 1:15 AMCommanders @ 49ers49ers 31-17Read

Every fixture in the round is covered across our NFL UK hub, and the 32 club pages sit on the NFL teams hub.

Cardinals vs Rams FAQ

What time is Cardinals vs Rams in the UK?

9.05pm BST on Sunday 18 October at SoFi Stadium, which is 4:05 PM ET.

How can I watch Cardinals vs Rams in the UK?

Sky Sports has the coverage and NFL Game Pass on DAZN carries every game of the season, live or on demand. Sky holds one exclusive pick in each of the Sunday 6pm and 9pm windows, and those two reach Game Pass 24 hours after the final whistle. Channel 5 and 5ACTION carry the week’s free-to-air games, and those are not blacked out.

Has Marvin Harrison Jr. left Arizona?

Yes, traded to Houston on 11 October.

Which team has conceded the most touchdowns?

Arizona, with 21 in five games.

18+ | Please gamble responsibly | BeGambleAware.org | Signal probabilities approximate at time of writing and subject to change