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Colts vs Jaguars Prediction, Picks & Odds

Indianapolis Colts vs Jacksonville Jaguars prediction, picks and odds for Week 8 of the 2026 NFL season

Jacksonville concede 3.23 yards a carry, the best run defense in the NFL, and have given up 11 touchdowns in six games. Our Colts vs Jaguars prediction sends a 69.4 passing game at them.

The Jacksonville Jaguars are 4-2 at +50 and back at EverBank after two home games in London. The Indianapolis Colts are 2-5 and Daniel Jones has four touchdown passes to seven interceptions.

Squawka Signal · Model vs market

Indianapolis Colts @ Jacksonville Jaguars

Week 8 · Sun Nov 1, 1:00 PM ET. Our Signal model makes the Jacksonville Jaguars favorites by about 9 points, a 80% win probability.

INDIndianapolis ColtsSquawka20%Market20%▬ Fair
JACJacksonville JaguarsSquawka80%Market80%▬ Fair
Projected lineJacksonville Jaguars -9

Squawka Signal is our model’s read against devigged market prices, updated after every result — not betting advice. How the NFL Signal works. 21+. Play responsibly. Full T&Cs & geo-restrictions apply: Kalshi, Polymarket, ProphetX.

Week 8 · Editorial pick

Colts vs Jaguars: our editor’s props

Two calls from our editor, to read next to Signal’s live numbers.

Colts AT Jaguars

Our props

TotalUnder 42.5 pointsJacksonville concede 3.23 a carry and 40.0% in the red zone, the best marks in the NFL. Indianapolis rate 69.4 through the air.
★★★☆☆3/5 confidence
Player propTrevor Lawrence 2+ passing touchdownsLawrence has 14 touchdown passes to four interceptions at 106.2. Indianapolis allow a 97.4 opponent rating.
★★★☆☆3/5 confidence

An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.

Colts vs Jaguars: 2026 form so far

A +50 team against a -26 team, and the gap is mostly one side of the ball. The table sets each attack against what the opposite defense has actually allowed.

Colts attack against the Jaguars defense

Per gameColts offenseJaguars allow
Passing yards180.4273.8
Rushing yards117.672.2
Yards per carry4.13.2
Passer rating69.487.7
Touchdowns2.01.8
Third-down conversion39.8%36.2%
Red-zone conversion60.0%40.0%
Sacks conceded / recorded2.71.8

Jaguars attack against the Colts defense

Per gameJaguars offenseColts allow
Passing yards234.8215.9
Rushing yards112.8124.4
Yards per carry4.14.8
Passer rating106.297.4
Touchdowns3.02.6
Third-down conversion47.9%30.0%
Red-zone conversion66.7%60.0%
Sacks conceded / recorded1.71.9

Jacksonville have conceded 11 touchdowns in six games, behind only Minnesota and Kansas City, and allow 40.0% in the red zone.

Colts vs Jaguars quarterback matchup

Trevor Lawrence has 14 touchdown passes to four interceptions at 106.2. Daniel Jones has four to seven at 69.4, the second-lowest team rating in the NFL.

TeamQuarterbackLast gameSeason to date
ColtsDaniel Jones13/22, 108 yds, 0 TD, 1 INT, 52.8 rtg143/240, 1398 yds, 4 TD, 7 INT, 69.4 rtg (7 games)
JaguarsTrevor Lawrence24/41, 306 yds, 4 TD, 1 INT, 104.3 rtg120/184, 1480 yds, 14 TD, 4 INT, 106.2 rtg (6 games)
Last game is Week 7 (Week 6 for Jacksonville, who was idle). Season figures are 2026 to date, with games played in brackets.

Colts vs Jaguars injury report and team news

Jacksonville concede 3.23 yards a carry, the lowest figure in the NFL.

Jacksonville allow 40.0% of red-zone trips to be converted, the fourth-best rate in the league.

Indianapolis rate 69.4 through the air, second-lowest in the NFL, and have conceded 19 sacks.

Injury report · Week 8Official game-status report — updates through the week
INDIndianapolis Colts
No game-status designations filed yet.
Out long-term
Cam Taylor-BrittCBIR
Cameron MitchellCBIR
Arden KeyDEIR
Micheal ClemonsDEIR
Carson TowtTEIR
Alec PierceWRIR
D.J. MontgomeryWRIR
JACJacksonville Jaguars
No game-status designations filed yet.
Out long-term
B.J. Green IIDEIR
Zach DurfeeDEIR
Jared BartlettLBIR
Parker HughesLBIR
Anton HarrisonOLIR
Garrett DiGiorgioOLIR
Patrick MekariOLIR
Sam MustipherOLIR
Caleb RansawSAFIR

The best run defense nobody is talking about

Three point two three yards a carry conceded — the best mark in the NFL — with 40.0% allowed in the red zone and 11 touchdowns given up in six games.

They score too: a 106.2 team passer rating and Trevor Lawrence on 14 touchdown passes to four interceptions.

Indianapolis are not equipped for it. Daniel Jones has thrown seven interceptions to four touchdowns, the Colts rate 69.4, and they have conceded 19 sacks.

Players to watch

  • Trevor Lawrence (JAC, QB): 1,480 passing yards and 14 touchdowns at 106.2.
  • Brian Thomas Jr. (JAC, WR): The first read in an offense converting 47.9% on third down.
  • Jonathan Taylor (IND, RB): 823 rushing yards at 4.12 a carry.
  • Tyler Warren (IND, TE): A central target in a passing game rating 69.4.

How to watch Colts vs Jaguars

Kickoff is 1:00 PM ET on Sunday, November 1 at EverBank Stadium, which is 12:00 PM CT and 10:00 AM PT. CBS has the regional broadcast.

DetailColts vs Jaguars
DateSunday, November 1, 2026
Kickoff1:00 PM ET / 12:00 PM CT / 10:00 AM PT
VenueEverBank Stadium, Jacksonville, FL
TVCBS
Live streamNFL+ / Paramount+
WeekWeek 8, 2026 NFL season

Colts vs Jaguars prediction and score projection

Jacksonville win 27-16. The Jaguars have the best run defense in the league and the Colts have the second-worst passing game, which is a short route to a comfortable afternoon.

Signal’s live read on this game updates through the week.

Every Week 8 game, previewed

Kickoff (ET)GameOur predictionPreview
Thu 8:15 PMPanthers @ PackersPackers 27-20Read
Sun 2:00 PMCardinals @ CowboysCowboys 27-17Read
Sun 2:00 PMFalcons @ BuccaneersBuccaneers 24-21Read
Sun 2:00 PMRavens @ BillsBills 27-20Read
Sun 2:00 PMBrowns @ SteelersSteelers 23-17Read
Sun 2:00 PMColts @ JaguarsJaguars 27-16You are here
Sun 2:00 PMRaiders @ JetsRaiders 23-20Read
Sun 2:00 PMVikings @ LionsVikings 24-21Read
Sun 2:00 PMTitans @ BengalsBengals 30-13Read
Sun 5:05 PMChargers @ RamsRams 26-16Read
Sun 5:25 PMChiefs @ BroncosChiefs 27-24Read
Sun 5:25 PMPatriots @ DolphinsPatriots 26-17Read
Sun 9:20 PMEagles @ CommandersEagles 20-17Read
Mon 9:15 PMBears @ SeahawksSeahawks 24-21Read

NFL predictions for the round and our NFL hub carry the rest of the card. The outright markets are priced in who wins the AFC. For the player side of this game, see player prop betting.

Colts vs Jaguars FAQ

Who is favored, the Colts or the Jaguars?

Jacksonville, clearly. Our Signal model has the Jaguars as strong favorites and the live number is in the Signal card on this page. Jacksonville are 4-2 at +50; Indianapolis are 2-5 at -26.

What time is Colts vs Jaguars?

1:00 PM ET on Sunday, November 1 at EverBank Stadium, which is 12:00 PM CT and 10:00 AM PT.

Which team has the best run defense?

Jacksonville, conceding 3.23 yards a carry — the lowest figure in the NFL.

Are Jacksonville back home?

Yes. This is their first game at EverBank after back-to-back home games in London.

21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change