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Colts vs Chiefs Prediction, Picks & Odds

Indianapolis Colts vs Kansas City Chiefs prediction, picks and odds for Week 2 of the 2026 NFL season

Our Colts vs Chiefs prediction lands on the home side in the Sunday night game. Squawka Signal’s live read updates on this page through the week.

The Indianapolis Colts allowed Baltimore 202 rushing yards and four rushing touchdowns in a 41-23 defeat. The Kansas City Chiefs ran for 216 against Denver on Monday night. Arrowhead is not where you want to arrive with that on your record.

Week 1 · Editorial pick

Colts vs Chiefs: our editor’s props

Two editorial calls to sit alongside the live Signal numbers on this page.

Colts AT Chiefs

Our props

Player propKenneth Walker 90+ rushing yardsWalker carried 23 times for 173 at 7.5 a carry against Denver, with a 60-yard long. Indianapolis conceded 202 rushing yards to Baltimore.
★★★★confidence
Player propJonathan Taylor 1+ rushing touchdownTaylor ran 19 times for 98 and scored twice against Baltimore. Kansas City conceded 61 rushing yards to Denver, so this is the harder half of the pair.
★★★★★confidence

An editorial call, not a Signal model output. 19+ (18+ in AB, MB and QC). Please play responsibly.

Colts vs Chiefs: 2026 form so far

One side controlled its opener on the ground. The other was controlled on the ground.

2026 season to dateColtsChiefs
Record0-11-0
Points for2331
Points against4110
Point differential-18+21
Total yards251392
Yards per play4.75.9
Turnovers21
Third-down offence30.0%52.9%
Red-zone offence100.0%60.0%
Sacks recorded24
Opponent passer rating124.269.2

Kansas City averaged 5.9 yards a play and conceded ten points. Indianapolis averaged 4.7 and conceded 41.

Colts vs Chiefs injury report and team news

Jonathan Taylor carried 19 times for 98 yards and scored twice against Baltimore. Daniel Jones threw for 166 with a touchdown and an interception.

This section updates as soon as the Out, Doubtful and Questionable tags land.

The matchup that settles it: Kenneth Walker against a run defence already exposed

Walker averaged 7.5 a carry against Denver with a 60-yard long. Indianapolis have just conceded 202 rushing yards to a Baltimore side doing much the same thing.

Taylor is the counter. He scored twice and ran for 98, though Kansas City held Denver to 61 yards on the ground.

Mahomes threw only 27 times on Monday. The Chiefs do not need him to throw 40 to win this kind of game.

Players to watch

  • Jonathan Taylor (IND, RB): 19 carries for 98 yards and two touchdowns against Baltimore.
  • Daniel Jones (IND, QB): 166 yards and a touchdown in the opener, with one interception.
  • Kenneth Walker (KC, RB): 173 rushing yards at 7.5 a carry against Denver.
  • Patrick Mahomes (KC, QB): Two touchdown passes on Monday night, from 27 attempts.

How to watch Colts vs Chiefs

The game kicks off at 8:20 PM ET on Sunday, September 20, which is 7:20 PM CT and 5:20 PM PT. The Canadian broadcast is on CTV or TSN depending on region, with RDS carrying the French-language call, and DAZN carries every game of the season. Squawka may earn a commission if you subscribe through that link.

DetailColts vs Chiefs
DateSunday, September 20, 2026
Kickoff8:20 PM ET / 7:20 PM CT / 5:20 PM PT
VenueArrowhead Stadium, Kansas City, MO
TVCTV / TSN (regional) / RDS (French)
Live streamDAZN (NFL Game Pass)
WeekWeek 2, 2026 NFL season

Colts vs Chiefs prediction and score projection

Our Colts vs Chiefs prediction is a Kansas City win, 30-20. The Chiefs run the ball and take it away, and Indianapolis have shown they can stop neither.

Signal’s live number updates on this page through the week.

Every fixture in the round is covered across our NFL hub, and Signal rates every Week 2 game the same way. Compare the AFC Championship odds and NFC Championship odds as the season develops, and our guide to watching the NFL in Canada covers every window.

Colts vs Chiefs FAQ

Who is favoured to win, the Colts or the Chiefs?

Kansas City, at home. The Chiefs are 1-0 after a 21-point win; Indianapolis conceded 41 points in their opener.

What time is Colts vs Chiefs in Canada?

8:20 PM ET on Sunday, September 20, which is 7:20 PM CT and 5:20 PM PT.

What channel is Colts vs Chiefs on in Canada?

CTV or TSN depending on region, with RDS carrying the French-language call. DAZN streams it too.

How did each side do in Week 1?

Indianapolis lost 41-23 to Baltimore. Kansas City beat Denver 31-10.

19+ (18+ in AB, MB and QC) | Please play responsibly | ConnexOntario: 1-866-531-2600 (ON) | Signal probabilities approximate at time of writing and subject to change