Arizona has conceded 23 touchdowns and allows a 116.5 opponent passer rating. Both are the worst figures in the NFL, and our Broncos vs Cardinals prediction finds the Cardinals hosting a 4-2 team.
The Arizona Cardinals are 2-4 at -52. The Denver Broncos allow a 73.1 opponent rating, second only to Minnesota, and sit 4-2 despite being outscored by 11.
Broncos vs Cardinals: our editor’s props
Two calls from our editor, to read next to Signal’s live numbers.
AT 
Our props
An editorial call, not a Signal model output. 19+ (18+ in AB, MB and QC). Please play responsibly.
Broncos vs Cardinals: 2026 form so far
The league’s worst pass defence against one of its best. The table pairs every attacking number with the defensive number sitting opposite it.
Broncos attack against the Cardinals defence
| Per game | Broncos offence | Cardinals allow |
|---|---|---|
| Passing yards | 168.0 | 229.7 |
| Rushing yards | 84.2 | 120.8 |
| Yards per carry | 3.4 | 4.4 |
| Passer rating | 79.4 | 116.5 |
| Touchdowns | 2.0 | 3.8 |
| Third-down conversion | 31.6% | 41.8% |
| Red-zone conversion | 61.1% | 71.4% |
| Sacks conceded / recorded | 1.3 | 2.3 |
Cardinals attack against the Broncos defence
| Per game | Cardinals offence | Broncos allow |
|---|---|---|
| Passing yards | 211.0 | 208.5 |
| Rushing yards | 96.3 | 139.8 |
| Yards per carry | 3.7 | 4.7 |
| Passer rating | 83.6 | 73.1 |
| Touchdowns | 2.0 | 2.2 |
| Third-down conversion | 39.3% | 44.4% |
| Red-zone conversion | 47.8% | 52.9% |
| Sacks conceded / recorded | 2.0 | 3.0 |
Denver is 4-2 and has been outscored by 11. That is the sort of record a defence drags a team to, and the numbers say exactly that.
Broncos vs Cardinals quarterback matchup
Bo Nix has six touchdown passes to three interceptions at 79.4 and threw for 107 yards last week. Jacoby Brissett has nine to six at 83.4.
| Team | Quarterback | Last game | Season to date |
|---|---|---|---|
| Broncos | Bo Nix | 17/27, 107 yds, 0 TD, 0 INT, 71.1 rtg | 114/189, 1049 yds, 6 TD, 3 INT, 79.4 rtg (6 games) |
| Cardinals | Jacoby Brissett | 24/35, 218 yds, 0 TD, 1 INT, 73.3 rtg | 156/234, 1328 yds, 9 TD, 6 INT, 83.4 rtg (6 games) |
Broncos vs Cardinals injury report and team news
Arizona has conceded 23 touchdowns in six games, more than any team in the NFL.
Arizona allows a 116.5 opponent passer rating, also the worst figure in the league.
Denver allows a 73.1 opponent rating, second only to Minnesota’s 62.9.
The worst pass defence in the league, and one of the best
Arizona concedes a 116.5 opponent rating and 23 touchdowns, both the worst marks in football, and lets opponents finish 71.4% of their red-zone trips.
Denver sits at the other end at 73.1 and has 18 sacks to go with it. On defence the Broncos are among the best three teams in the league.
What stops this being a rout is Denver’s own attack. The Broncos run for 3.44 a carry and convert 31.6% on third down, both among the three worst marks in the NFL.
Players to watch
- Bo Nix (DEN, QB): Six touchdown passes at a 79.4 rating.
- RJ Harvey (DEN, RB): Splits a backfield at 3.44 a carry.
- Jacoby Brissett (ARI, QB): 1,328 yards and nine scores at 83.4.
- Trey McBride (ARI, TE): Arizona’s leading target since the Harrison trade.
How to watch Broncos vs Cardinals in Canada
Kickoff is 4:05 PM ET on Sunday, October 25 at State Farm Stadium in Glendale. CTV’s Sunday afternoon pick varies by region, so your local listings decide whether this is the game you get. RDS carries the French-language broadcast. DAZN carries every game of the season in Canada through NFL Game Pass. Squawka may earn a commission if you subscribe through that link.
| Detail | Broncos vs Cardinals |
|---|---|
| Date | Sunday, October 25, 2026 |
| Kickoff | 4:05 PM ET / 3:05 PM CT / 1:05 PM PT |
| Venue | State Farm Stadium, Glendale, AZ |
| TV | CTV (regional) / TSN / RDS (French) |
| Live stream | DAZN (NFL Game Pass) |
| Week | Week 7, 2026 NFL season |
Broncos vs Cardinals prediction and score projection
Our Broncos vs Cardinals prediction is Denver by 26-17. Arizona concedes more touchdowns than anyone and Denver’s defence is second-best in the league by rating.
Signal’s live probability for this game updates through to kickoff.
Every Week 7 game, previewed
| Kickoff (ET) | Game | Our prediction | Preview |
|---|---|---|---|
| Thu 8:15 PM | Patriots @ Bears | Patriots 24-21 | Read |
| Sun 9:30 AM | Steelers @ Saints | Steelers 27-20 | Read |
| Sun 1:00 PM | Bengals @ Ravens | Ravens 27-23 | Read |
| Sun 1:00 PM | Browns @ Titans | Browns 20-16 | Read |
| Sun 1:00 PM | Colts @ Vikings | Vikings 27-13 | Read |
| Sun 1:00 PM | Dolphins @ Jets | Jets 20-16 | Read |
| Sun 1:00 PM | Giants @ Texans | Texans 23-17 | Read |
| Sun 1:00 PM | 49ers @ Falcons | 49ers 30-20 | Read |
| Sun 1:00 PM | Buccaneers @ Panthers | Panthers 24-20 | Read |
| Sun 4:05 PM | Broncos @ Cardinals | Broncos 26-17 | You are here |
| Sun 4:25 PM | Packers @ Lions | Lions 27-24 | Read |
| Sun 4:25 PM | Rams @ Raiders | Rams 27-23 | Read |
| Sun 8:20 PM | Chiefs @ Seahawks | Chiefs 24-23 | Read |
| Mon 8:15 PM | Cowboys @ Eagles | Eagles 23-20 | Read |
Our NFL hub carries the full card, and Signal rates every Week 7 game on the same model. An inter-conference game, which means the AFC Championship odds and the NFC Championship odds are each in play rather than just one of them.
Broncos vs Cardinals FAQ
Denver. Our Signal model has the Broncos as clear favourites, with the live number in the Signal card on this page. Denver is 4-2; Arizona is 2-4 at -52.
4:05 PM ET on Sunday, October 25, which is 3:05 PM CT and 1:05 PM PT, at State Farm Stadium.
CTV’s Sunday afternoon game is a regional pick, so check your local listings. RDS has the French call. DAZN carries every game of the season in Canada through NFL Game Pass.
Arizona, with 23 in six games.
19+ (18+ in AB, MB and QC) | Please play responsibly | ConnexOntario: 1-866-531-2600 (ON) | Signal probabilities approximate at time of writing and subject to change