Santos Laguna vs Tigres UANL: Predictions, Picks, Odds & Lineups

Santos Laguna host Tigres UANL at Estadio Corona on Saturday, August 29 (11:00 PM ET / 10:00 PM CT / 8:00 PM PT).

Santos Laguna’s team news carries no fresh fitness concerns after the defeat at Puebla, with Ezequiel Bullaude — the squad leader with 14 shots and 4 on target — expected to spearhead the attack alongside Francisco Villalba, whose team-high 11 chances created make him the main creative outlet. Tigres UANL, with no absentees flagged either, will again build around Juan Francisco Brunetta, who has produced 3 goals, 3 assists and 17 chances created from 449 minutes this season.

Santos Laguna have conceded in matches like the 3-2 loss at Club Puebla and the 3-2 loss at Monterrey, and with Brunetta carrying that kind of end product for Tigres UANL, this looks set to be a game where both defenses are breached again. Tigres’ own results this season — a draw and three losses to go with the 1 win in their last five — mean it won’t be one-way traffic, but their extra firepower in attack should be enough to get across the line.

US viewers can watch Santos Laguna vs Tigres UANL on ViX, TUDN or Fox.

Santos Laguna vs Tigres UANL: Best Bets & Predictions

Our Signal model backs Tigres UANL to win 1-2 at Estadio Corona, with goals expected at both ends.

Where are you following from? Odds & offers below update to match.

🇺🇸 United StatesTrade on Kalshi 🌎 Outside the USOdds via bet365

Tigres UANLTop pickTigres UANL arrive with 4 points from 5 matches (1 win, 1 draw, 3 losses), a healthier return than a Santos Laguna side that has lost 5 in a row, including home defeats to Chivas and Atlas FC.

56%win prob.opening soon @ bet365

1-2 Santos LagunaJuan Francisco Brunetta has scored three goals and created 17 chances in the Apertura, enough to see Tigres UANL edge a tight one on the road while Santos Laguna's Ezequiel Bullaude, who already has 1 goal and seven chances created this season, gets his side on the scoresheet too.

⭐⭐⭐⭐⭐chanceopening soon @ bet365

YesSantos Laguna have scored in defeats like the 3-2 loss at Club Puebla and the 3-2 loss at Monterrey, and Tigres UANL have shared goals in matches such as the 2-2 draw with Atletico San Luis and the 3-1 loss at Club Tijuana, a trend that points to goals at both ends again here.

62%chanceopening soon @ bet365

Over 2.5Games involving both sides have produced multiple goals already this season — Santos Laguna's 3-2 loss at Monterrey and 3-0 loss at Club America, and Tigres UANL's 3-2 loss at Queretaro FC and 2-2 draw with Atletico San Luis — a pattern that supports another game going over 2.5 goals.

64%chanceopening soon @ bet365

Anytime Goalscorer: Juan Francisco BrunettaJuan Francisco Brunetta leads all listed attackers with 3 goals, 3 assists and 17 chances created from 449 minutes this Apertura, the standout attacking weapon in this fixture.

⭐⭐⭐⭐⭐chanceopening soon @ bet365

Our approach: we weigh recent form, underlying player numbers and league context to land on the picks below, then back each one with the stats behind it.

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Season Form & Standings

Tigres UANL have played 5, winning 1, drawing 1 and losing 3 for 4 points and a goal difference of -2, a return that leaves them still chasing a spot inside the Liguilla places via the reclasificacion. Santos Laguna’s own league table entry shows a blank return so far this Apertura, with the form guide the clearer picture: five straight losses coming into this one.

Liga MX

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Potential Match-Winners

• Ezequiel Bullaude (Santos Laguna): Ezequiel Bullaude has managed 1 goal and created 7 chances in 423 minutes, leading the squad with 14 shots and 4 on target.
• Francisco Villalba (Santos Laguna): Francisco Villalba has created a team-high 11 chances and added 1 assist in 390 minutes, the creative fulcrum Santos Laguna will lean on.
• Juan Francisco Brunetta (Tigres UANL): Juan Francisco Brunetta has scored three goals, created 17 chances and racked up 28 shots (10 on target) in 449 minutes, numbers no one else in this fixture gets close to.

Recent Form

Santos Laguna: L L L L L

• 2026-08-22: Club Puebla 3-2 Santos Laguna (L, away)
• 2026-08-16: Santos Laguna 0-1 Chivas (L, home)
• 2026-08-02: Club America 3-0 Santos Laguna (L, away)
• 2026-07-25: Santos Laguna 0-1 Atlas FC (L, home)
• 2026-07-18: Monterrey 3-2 Santos Laguna (L, away)

Santos Laguna have lost 5 straight: 3-2 at Club Puebla, 0-1 at home to Chivas, 3-0 at Club America, 0-1 at home to Atlas FC and 3-2 at Monterrey.

Tigres UANL: L D L L W

• 2026-08-21: Tigres UANL 2-0 Atlante FC (W, home)
• 2026-08-15: Atlas FC 2-1 Tigres UANL (L, away)
• 2026-08-01: Queretaro FC 3-2 Tigres UANL (L, away)
• 2026-07-25: Tigres UANL 2-2 Atletico San Luis (D, home)
• 2026-07-16: Club Tijuana 3-1 Tigres UANL (L, away)

Tigres UANL read L D L L W across their last 5: a 2-0 home win over Atlante FC, 2-1 away loss at Atlas FC, 3-2 away loss at Queretaro FC, 2-2 home draw with Atletico San Luis and 3-1 away loss at Club Tijuana.

Santos Laguna vs Tigres UANL Prediction

Tigres UANL have picked up 4 points from 5 matches, form that might not sound electric but still puts them ahead of a Santos Laguna side toting 5 straight defeats. Santos Laguna have conceded in matches like the 3-2 loss at Club Puebla and the 3-2 loss at Monterrey, and Tigres UANL’s Juan Francisco Brunetta, with 3 goals and 17 chances created already this season, gives the visitors the sharper edge in a game that should see goals at both ends. We see Tigres UANL winning 1-2 at Estadio Corona.