Santos Laguna vs Queretaro FC: Predictions, Picks, Odds & Lineups

Santos Laguna host Queretaro FC at Estadio Corona on Saturday, October 17 (7:00 PM ET / 6:00 PM CT / 4:00 PM PT).

No fresh fitness or suspension concerns have been flagged for either side ahead of this one, which should mean close to full-strength squads for both managers at Estadio Corona. Santos Laguna will again lean on midfielder Ezequiel Bullaude, who has 3 goals and 18 chances created in 933 minutes this season, alongside fellow midfielder Francisco Villalba, who has created 27 chances and added 2 goals of his own. Queretaro FC travel with defensive midfielder Santiago Homenchenko and striker Ali Avila both in line to start, the pair responsible for 9 of their side’s goals between them this season.

Expect a tight, low-event contest in Torreon. Santos Laguna have won 4 of 11 games this season and sit on 13 points with a -4 goal difference, numbers that reflect 6 defeats already picked up. Queretaro FC arrive in far better shape, taking 20 points from 10 matches with a +7 goal difference, winning 6 of those outings and losing just 2. With Santos Laguna’s form reading D L W W W against Queretaro FC’s W W D W W, this has the look of a scrappy, single-goal affair rather than an end-to-end shootout.

US viewers can watch Santos Laguna vs Queretaro FC on ViX, TUDN or Fox.

Season Form & Standings

Santos Laguna have taken 13 points from 11 games this season, with a -4 goal difference underlining defensive issues that have brought 6 defeats already. Queretaro FC, by contrast, have been one of the form sides of the campaign, racking up 20 points from 10 matches with a +7 goal difference, built on 6 wins and only two losses. Both sides remain in the Liguilla conversation as Liga MX’s regular season plays out, though it is Queretaro FC doing the heavy lifting at the top end of the form table.

Liga MX

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Potential Match-Winners

• Ezequiel Bullaude (Santos Laguna): The midfielder has 3 goals and a team-high 18 chances created in 933 minutes this season, the creative hub for Santos Laguna’s attack.
• Santiago Homenchenko (Queretaro FC): The defensive midfielder leads Queretaro FC with 5 goals this season from 25 shots and 16 chances created, as much a threat from deep and on set pieces as a shield in front of the defense.
• Ali Avila (Queretaro FC): The striker has scored 4 goals from 21 shots, 9 of them on target, making him the most direct route to goal for Queretaro FC’s front line.

Recent Form

Santos Laguna: D L W W W

• 2026-09-26: Santos Laguna 1-0 Pachuca (W, home)
• 2026-09-20: Toluca 2-3 Santos Laguna (W, away)
• 2026-09-13: Santos Laguna 2-1 FC Juarez (W, home)
• 2026-09-06: Cruz Azul 1-0 Santos Laguna (L, away)
• 2026-08-29: Santos Laguna 0-0 Tigres UANL (D, home)

D L W W W – Santos Laguna’s last league outing was a 1-0 home win over Pachuca.

Queretaro FC: W W D W W

• 2026-10-10: Queretaro FC 2-0 Atlante FC (W, home)
• 2026-09-26: Chivas 0-2 Queretaro FC (W, away)
• 2026-09-20: Queretaro FC 1-1 Club Leon (D, home)
• 2026-09-11: Club Tijuana 0-1 Queretaro FC (W, away)
• 2026-08-29: Atlas FC 1-3 Queretaro FC (W, away)

W W D W W – Queretaro FC’s last league outing was a 2-0 home win over Atlante FC.

Santos Laguna vs Queretaro FC Prediction

This looks set to be a cagey night in Torreon that finishes 0-1 to Queretaro FC. The visitors arrive on 20 points from 10 games with a +7 goal difference, numbers that dwarf a Santos Laguna side on 13 points and -4 from 11 outings, and with both teams well capable of shutting up shop, a single Queretaro FC goal – most likely from Ali Avila or Santiago Homenchenko, who have 9 goals between them this season – should be enough to decide it.