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Santos Laguna vs Club Leon: Predictions, Picks, Odds & Lineups

Santos Laguna vs Club Leon predicted formations

Santos Laguna host Club Leon at Estadio Corona on Saturday, November 21 (6:00 PM ET / 5:00 PM CT / 3:00 PM PT).

No fresh fitness concerns have been flagged for either side ahead of this one. Santos Laguna will again lean on Tahiel Jimenez Sanchez, who has scored 6 goals in just 401 minutes this season, with midfielder Ezequiel Bullaude supplying the service after racking up 21 chances created and 5 assists. Club Leon counter with Jose Alfonso Alvarado Perez, their top scorer on 6 goals, and Diber Cambindo Abonia, who leads the squad with 43 shots and 17 on target.

This one looks built for a tight, low-scoring finish rather than an end-to-end shootout. Santos Laguna’s +3 goal difference and Club Leon’s +2 both point to sides that win and lose by small margins, and with home advantage at Estadio Corona in their favor, Santos Laguna look best placed to find the single goal that settles it.

US viewers can watch Santos Laguna vs Club Leon on ViX, TUDN or Fox.

Squawka Signal
Match outcome · who wins
Santos LagunaSantos Laguna46%mkt 40%Our pick
DrawDraw25%mkt 22%
Club LeonClub Leon29%mkt 37%

Santos Laguna vs Club Leon: Best Bets & Predictions

The market prices Both teams: No at 30%. Signal says 43%.

+13points of value · both teams to score
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The tips · best bets
MarketMkt %Signal %Read
Correct ScoreSantos Laguna 1-0 Club LeonTahiel Jimenez Sanchez has already scored 6 goals in just 401 minutes this season, enough quality up top to settle a tight, low-scoring game by a single goal.
—
10%
Model read
Both Teams to ScoreBoth teams: NoSantos Laguna's +3 goal difference and Club Leon's +2 both reflect games settled by fine margins, and this one looks like it will only open up at one end of the field.
30%
43%
Strong value
Over / Under 2.5Under 2.5Neither side has the goal difference of a high-scoring team, with Santos Laguna at +3 and Club Leon at +2 across 16 games apiece, backing a low-scoring script.
35%
46%
Strong value
Anytime ScorerTahiel Jimenez Sanchez to score anytimeJimenez Sanchez has scored 6 goals in just 401 minutes this season, the sharpest scoring rate of anyone involved in this fixture.
—
36%
Model read
Signal edge callsRecord building · settles at full-time

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Season Form & Standings

Santos Laguna sit on 25 points from 16 games (8 wins, 1 draw, 7 losses, goal difference +3), just 2 points clear of Club Leon’s 23 points (6 wins, 5 draws, 5 losses, goal difference +2) in the Liga MX Apertura table, with both clubs still jockeying for position in the race toward the Liguilla.

Liga MX

TeamPosGPWDLGFGAGDPts
Santos Laguna6168172320+325
Club Leon7166552321+223
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Team News Predicted

Santos Laguna vs Club Leon Predicted Lineups

Predicted XI — updated for the latest team news.

Santos Laguna

5-4-1
C. Acevedo
E. Echeverria
J. Perez
F. Sanchez
F. Pardo
M. Cuevas
E. Bullaude
F. Caseres
Fran Villalba
E. Aguirre
E. Lozano

Club Leon

4-4-2
O. Garcia
S. Vegas
J. Guevara
J. Romana
I. Moreno
D. Arcila
F. Beltran
I. Rodriguez
R. Echeverria
A. Alvarado
D. Cambindo
    Squawka · Team News

    Potential Match-Winners

    • Tahiel Jimenez Sanchez (Santos Laguna): 6 goals in just 401 minutes is an outrageous scoring rate, making him the most direct route to a Santos Laguna goal.
    • Ezequiel Bullaude (Santos Laguna): 21 chances created and 5 assists make him Santos Laguna’s chief creator, with 3 goals of his own from midfield.
    • Diber Cambindo Abonia (Club Leon): 43 shots and 17 shots on target this season, with 4 goals already, make him Leon’s most persistent threat.

    Recent Form

    Santos Laguna: W W L W W

    • 2026-11-07: Atlante FC 0-2 Santos Laguna (W, away)
    • 2026-11-01: Santos Laguna 1-0 Necaxa (W, home)
    • 2026-10-25: Club Tijuana 4-1 Santos Laguna (L, away)
    • 2026-10-21: Santos Laguna 2-0 Pumas UNAM (W, home)
    • 2026-10-17: Santos Laguna 5-0 Queretaro FC (W, home)

    Santos Laguna’s form reads W-W-L-W-W: a 5-0 win over Queretaro FC and a 2-0 win over Pumas UNAM either side of a 4-1 loss at Club Tijuana, then a 1-0 home win over Necaxa and a 2-0 win away at Atlante FC.

    Club Leon: L W D L D

    • 2026-11-09: Club Leon 1-1 Chivas (D, home)
    • 2026-11-01: Cruz Azul 2-1 Club Leon (L, away)
    • 2026-10-24: Club Leon 1-1 Toluca (D, home)
    • 2026-10-20: Tigres UANL 0-2 Club Leon (W, away)
    • 2026-10-17: Club Leon 3-5 Club America (L, home)

    Club Leon’s form reads L-W-D-L-D: a 3-5 home loss to Club America, a 2-0 win away at Tigres UANL, a 1-1 draw with Toluca, a 2-1 loss at Cruz Azul, and a 1-1 draw with Chivas most recently.

    Santos Laguna vs Club Leon Prediction

    This sets up as a tight one. Santos Laguna’s 25 points and +3 goal difference from 16 games give them the slightly stronger platform over Club Leon’s 23 points and +2, and with Tahiel Jimenez Sanchez in such sharp scoring form, the Signal model’s call is a narrow 1-0 win for Santos Laguna at Estadio Corona.

    Squawka Signal

    Our model rates every Liga MX fixture — see the numbers behind Santos Laguna v Club Leon.

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