Club Puebla vs Atletico San Luis: Predictions, Picks, Odds & Lineups

Club Puebla host Atletico San Luis at Estadio Cuauhtemoc on Friday, November 20 (8:00 PM ET / 7:00 PM CT / 5:00 PM PT).

Club Puebla go into this one with no fresh injury or suspension concerns to navigate, and the attacking pieces that have carried them through the Apertura are available: striker Eduardo Mustre Torres and midfielder Omar Moreno Villegas have each scored three goals this season, while Kevin Velasco Bonilla’s nineteen chances created leads the group from midfield. Atletico San Luis arrive with a clean bill of health too, built around attacking midfielder Rafael Llorente Sanz, who leads this fixture with four goals and twenty chances created, alongside David Rodriguez Uribe, who has added three goals of his own from a similar creative role.

Both sides have shown they can be cut open at the back as often as they create chances going forward, which points to a tighter, lower-scoring night than the underlying goal totals might suggest. Puebla will lean on the platform that produced their away win at Queretaro FC to control territory at Estadio Cuauhtemoc, while San Luis arrive off back-to-back home defeats to Atlas FC and FC Juarez and need a response from their attacking midfield pairing. Expect a cagey night decided by a single moment rather than an open, end-to-end contest.

US viewers can watch Club Puebla vs Atletico San Luis on ViX, TUDN or Fox.

Season Form & Standings

This one sits inside Liga MX’s congested Liguilla and reclasificacion picture, where the margins between sides are thin enough that recent form tells us more than any single league placing. Both Puebla and San Luis have shown they can win and lose in quick succession this Apertura, which is exactly the kind of matchup where a tight, low-scoring result makes sense.

Liga MX

Potential Match-Winners

• Eduardo Mustre Torres (Club Puebla): The striker has three goals from fifteen shots and six on target this season, making him Puebla’s most direct route to goal in this one.
• Kevin Velasco Bonilla (Club Puebla): The midfielder has created a team-high nineteen chances to go with two goals this season, the clearest playmaking threat in Puebla’s side.
• Rafael Llorente Sanz (Atletico San Luis): The attacking midfielder tops this matchup with four goals and twenty chances created, the most dangerous attacking influence on either side.

Recent Form

Club Puebla: D L L L W

• 2026-11-09: Queretaro FC 0-2 Club Puebla (W, away)
• 2026-10-30: Club Puebla 1-2 Pumas UNAM (L, home)
• 2026-10-25: Atlas FC 4-3 Club Puebla (L, away)
• 2026-10-21: Club Puebla 1-4 Monterrey (L, home)
• 2026-10-16: Club Tijuana 0-0 Club Puebla (D, away)

Club Puebla’s form sheet shows a draw at Club Tijuana (0-0), a home loss to Monterrey (1-4), a loss away to Atlas FC (4-3), a home loss to Pumas UNAM (1-2), and a win away at Queretaro FC (2-0) immediately before this trip.

Atletico San Luis: D W W L L

• 2026-11-07: Atletico San Luis 0-1 FC Juarez (L, home)
• 2026-10-30: Atletico San Luis 0-1 Atlas FC (L, home)
• 2026-10-23: Atlante FC 0-1 Atletico San Luis (W, away)
• 2026-10-20: Atletico San Luis 2-1 Queretaro FC (W, home)
• 2026-10-17: Toluca 1-1 Atletico San Luis (D, away)

Atletico San Luis’s form sheet shows a draw at Toluca (1-1), back-to-back wins over Queretaro FC (2-1) and away at Atlante FC (0-1), then consecutive home defeats to Atlas FC (0-1) and FC Juarez (0-1) heading into this trip.

Club Puebla vs Atletico San Luis Prediction

This has the feel of a tight, low-event Liga MX night, and our Signal model backs Club Puebla to find the one moment that matters. Puebla’s attack carries the scoring edge through Mustre Torres and Moreno Villegas, both with three goals this season, and that should be enough to break down a San Luis side that has gone back-to-back home games without scoring. San Luis still carry threat through Llorente Sanz and Rodriguez Uribe, but on a night we expect few clean looks at goal for either side, we’re backing a 1-0 win for Club Puebla, with the game staying under 2.5 goals and both teams to score going against.