Pisa host Napoli in a clash that carries huge significance at both ends of the Serie A table.
The action kicks off at 11:30am (UK time) on Sunday at the Arena Garibaldi, with Napoli pushing to secure second place and Pisa desperately seeking a rare highlight in a difficult campaign. Napoli won a five-goal thriller when these sides last met, and with both teams having much to play for, the return fixture promises plenty of drama.
Best Bets & Predictions
Based on season-long trends and head-to-head history, here are our top betting recommendations for Pisa vs Napoli. We’re particularly confident in backing Napoli to win due to their clear superiority in attack and defence.
| Our Prediction | Odds & Bookmaker | Confidence | Why We’re Backing It |
|---|---|---|---|
| Napoli to Win | 4/11 @ Bet365 (73.3%) | ⭐⭐⭐⭐ | We are backing Napoli because they have scored more than double Pisa’s goals this season (54 vs 25), have a much stronger defence, and won the reverse fixture. Pisa have managed just two wins all campaign. |
| Over 2.5 Goals | 8/11 @ Bet365 (57.9%) | ⭐⭐⭐ | Napoli’s firepower and Pisa’s defensive frailty suggest this could be another high-scoring affair, much like their previous encounter which saw five goals. |
Odds correct at the time of writing.
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Season Form & Standings
The 2025/26 Serie A season has seen a stark contrast between these two clubs. Napoli sit comfortably in second place, chasing a Champions League berth, while Pisa are rooted to the bottom and have had their relegation confirmed. Here’s how things stand after 36 games:
| Team | Pos | P | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| Napoli | 2 | 36 | 21 | 7 | 8 | 54 | 36 | +18 | 70 |
| Pisa | 20 | 36 | 2 | 12 | 22 | 25 | 66 | -41 | 18 |
Napoli’s goal difference (+18) and consistent winning record underline their status as heavy favourites, while Pisa’s defensive woes (66 conceded) and just two wins illustrate the challenge they face.
Potential Match-Winners
- Romelu Lukaku (Napoli): Known for his strength and hold-up play, Lukaku is a proven scorer at this level. While his exact goal tally this season isn’t provided, Napoli’s 54 goals suggest he’ll be central to their attacking threat.
- Matteo Politano (Napoli): Offers creativity and a goal threat from wide areas. His ability to cut inside and shoot could trouble Pisa’s struggling defence.
- Rafiu Durosinmi (Pisa): As one of Pisa’s main attacking outlets, Durosinmi will need to make the most of any chances if Pisa are to trouble Napoli’s back line.
- Simone Scuffet (Pisa): Pisa’s goalkeeper has made 99 saves this season – one of the busiest in the division. He’ll need another big game to keep his side in contention.
With Napoli having scored over twice as many goals as Pisa and boasting a much higher shot accuracy (38.85% vs 33.19%), their attacking stars look well placed to make a difference.
Head-to-Head: Last Meeting
These sides have only met once recently, in a dramatic 3-2 win for Napoli earlier this season. Goals flowed at both ends in that clash, suggesting another lively encounter may be on the cards.
| Date | Score | Competition |
|---|---|---|
| 22/09/25 | Napoli 3-2 Pisa | Serie A |
Conclusion: Can Napoli Avoid a Slip-up?
Napoli arrive as clear favourites, with the best attack and a much more robust defence compared to Pisa. The home side’s tendency to concede, combined with Napoli’s relentless forward play, points strongly towards an away win. However, Pisa did score twice in Naples and could make life awkward if they take their chances. Will Napoli’s superior class tell, or can Pisa spring a surprise? Our advice is to back Napoli at 4/11 with Bet365 (73.3%) to get the job done.
Odds correct at the time of writing. Please gamble responsibly.
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