
Betting markets are not available yet.
- Live
- Kick Off
Internazionale vs Shakhtar Donetsk predictions for tonight’s 8pm (UK time) kick-off find Internazionale 29th after two Champions League defeats, with an unbeaten Shakhtar Donetsk side sitting 18 places higher arriving at the Stadio Giuseppe Meazza.
Anthony Eadson’s Internazionale vs Shakhtar Donetsk predictions, best bets and score prediction for Wednesday’s 8pm (UK time) kick-off are below.
Premium Tips
We expect goals in Milan, so our tips lean into the attacking names on show.
| Premium Tip | Odds | Why we’re backing it |
|---|---|---|
| Marcus Thuram to score anytime | 8/11 (Paddy Power) | Internazionale may be winless and in the bottom third, but they have still scored four times in two matches, so the chances are being created. Thuram leads their line and both of Inter’s games have flown past three goals, with Shakhtar having conceded in each of their outings so far. With Inter heavy favourites at 1/5 and chasing a first win of the campaign, plenty of their best work will run through the front man. |
| Piotr Zielinski to assist anytime | 9/2 (Ladbrokes) | Inter’s problems have been at the back rather than in attack, with six conceded but four scored across their opening two games. Zielinski’s set-piece delivery and range of passing give him a genuine route to a goal involvement against a Shakhtar side yet to keep a clean sheet this campaign. Both teams have found the net in each of their matches so far, and if the hosts rack up the chances we expect, the Pole is well placed to tee one up. |
18+ only. Please gamble responsibly. GambleAware — gambleaware.org · Odds correct at time of publishing.
How Internazionale go into the game
Internazionale have endured a miserable start, losing both their opening fixtures to sit 29th with no points. They have scored four but conceded six and are yet to register a clean sheet.
Their latest setback was a chaotic 4-3 home defeat to Club Brugge, and that followed a 2-1 loss away at Real Madrid on the opening night. The goals are there at one end, but the leaks at the other have cost them dearly.
How Shakhtar Donetsk go into the game
Shakhtar Donetsk are the early overachievers here, unbeaten and 11th on four points from their two games. Four goals scored and two conceded point to a side comfortable at both ends of the pitch.
They warmed up for this with a 3-1 home win over AEK Athens, having opened their campaign with a 1-1 draw away at PSV. That road result shows they can dig in away from home, which bodes well for a trip to Milan.

Internazionale vs Shakhtar Donetsk head-to-head
| Date | Home | Score | Away |
|---|---|---|---|
| 24/11/21 | Internazionale | 2-0 | Shakhtar Donetsk |
| 28/09/21 | Shakhtar Donetsk | 0-0 | Internazionale |
| 09/12/20 | Internazionale | 0-0 | Shakhtar Donetsk |
| 27/10/20 | Shakhtar Donetsk | 0-0 | Internazionale |
| 17/08/20 | Internazionale | 5-0 | Shakhtar Donetsk |
Recent history between the pair is tight at the back, with three of their last five meetings finishing goalless. Inter did win the two decisive ones, though, including a 5-0 rout in 2020.
Internazionale vs Shakhtar Donetsk predictions & betting tips
| Our Prediction | Odds & Bookmaker | Confidence | Why We’re Backing It |
|---|---|---|---|
| Internazionale win | 1/5 (bet365) | ⭐⭐⭐ | The hosts are strong favourites at home despite their form, with Shakhtar yet to face a side of Inter’s attacking calibre this campaign. |
| Both teams to score – Yes | 8/11 (bet365) | ⭐⭐⭐⭐ | Inter have conceded in both games and Shakhtar have found the net in each of their two outings, including three against AEK Athens. |
| Over 2.5 goals | 3/10 (bet365) | ⭐⭐⭐⭐ | Inter’s games have produced seven and three goals respectively, while Shakhtar’s win over AEK Athens brought four between the sides. |
| Correct score Internazionale 2-1 Shakhtar Donetsk | 9/1 (bet365) | ⭐⭐ | Inter’s firepower should edge it, but their shaky defence means Shakhtar can expect a goal of their own. |
Internazionale vs Shakhtar Donetsk score prediction
Form says caution, but class and home advantage should just about edge it. Inter have leaked six goals in two games, yet Shakhtar have scored in both of theirs, pointing to action at both ends of the pitch. Score prediction: Internazionale 2-1 Shakhtar Donetsk.


