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    Squawka / NFL News / NFL Predictions 2026: Squawka Signal’s AI Picks

    NFL Predictions 2026: Squawka Signal’s AI Picks

    Squawka Signal is our in-house NFL model, and this is its call on every game — a winner, a win probability and the projected spread for each fixture, refreshed every week. It is the same engine behind our power rankings and Super Bowl odds, pointed at the week ahead.

    Every pick is locked before kickoff and graded afterwards, straight-up and against the spread, so the record below is a real one that builds through the season — not a number we can tidy up after the fact.

    Squawka Signal · NFL AI Predictor

    Week 1 NFL Predictions

    The Squawka Signal model’s call on every game this week — the winner, a win probability and the projected spread — each linked to the full preview, with a running record of how the calls have gone.

    New for 2026 — the record starts this week and builds through the season.
    Week 1
    MatchSignal pickWin %
    NE New England Patriots @ Seattle Seahawks SEAThu Sep 10, 1:20am BST
    Seattle Seahawks to winSEA -2.0
    58%
    Bet bet365
    SF San Francisco 49ers @ Los Angeles Rams LAFri Sep 11, 1:35am BST
    Los Angeles Rams to winLA -2.7
    60%
    Bet bet365
    CHI Chicago Bears @ Carolina Panthers CARSun Sep 13, 6:00pm BST
    Chicago Bears to winCHI -3.3
    62%
    Bet bet365
    BAL Baltimore Ravens @ Indianapolis Colts INDSun Sep 13, 6:00pm BST
    Baltimore Ravens to winBAL -2.6
    60%
    Bet bet365
    ATL Atlanta Falcons @ Pittsburgh Steelers PITSun Sep 13, 6:00pm BST
    Pittsburgh Steelers to winPIT -4.2
    65%
    Bet bet365
    CLE Cleveland Browns @ Jacksonville Jaguars JACSun Sep 13, 6:00pm BST
    Jacksonville Jaguars to winJAC -10.3
    83%
    Bet bet365
    TB Tampa Bay Buccaneers @ Cincinnati Bengals CINSun Sep 13, 6:00pm BST
    Cincinnati Bengals to winCIN -3.0
    61%
    Bet bet365
    NYJ New York Jets @ Tennessee Titans TENSun Sep 13, 6:00pm BST
    Tennessee Titans to winTEN -0.1
    50%
    Bet bet365
    NO New Orleans Saints @ Detroit Lions DETSun Sep 13, 6:00pm BST
    Detroit Lions to winDET -6.7
    73%
    Bet bet365
    BUF Buffalo Bills @ Houston Texans HOUSun Sep 13, 6:00pm BST
    Buffalo Bills to winBUF -0.7
    53%
    Bet bet365
    ARI Arizona Cardinals @ Los Angeles Chargers LACSun Sep 13, 9:25pm BST
    Los Angeles Chargers to winLAC -8.1
    78%
    Bet bet365
    GB Green Bay Packers @ Minnesota Vikings MINSun Sep 13, 9:25pm BST
    Green Bay Packers to winGB -0.5
    52%
    Bet bet365
    MIA Miami Dolphins @ Las Vegas Raiders LVSun Sep 13, 9:25pm BST
    Miami Dolphins to winMIA -1.9
    57%
    Bet bet365
    WAS Washington Commanders @ Philadelphia Eagles PHISun Sep 13, 9:25pm BST
    Philadelphia Eagles to winPHI -6.5
    73%
    Bet bet365
    DAL Dallas Cowboys @ New York Giants NYGMon Sep 14, 1:20am BST
    Dallas Cowboys to winDAL -0.3
    51%
    Bet bet365
    DEN Denver Broncos @ Kansas City Chiefs KCTue Sep 15, 1:15am BST
    Denver Broncos to winDEN -3.4
    63%
    Bet bet365

    The model’s pick locks before kickoff and is graded straight-up and against the spread after the game — that is the running record above. Win probability and the projected line come from tens of thousands of season simulations. A model read, not a betting tip. 18+. BeGambleAware.org. Please gamble responsibly. How the model works.