
Napoli welcome Chelsea to the Stadio Diego Armando Maradona in the UEFA Champions League on Wednesday at 8:00pm. Napoli need a victory to avoid being eliminated from the competition, while three points for Chelsea could see them finish in the top-8. Find our match preview and best bets below.
Best Bets & Predictions
| Our Prediction | Odds & Bookmaker | Confidence | Why We’re Backing It |
|---|---|---|---|
| Over 2.5 goals | 4/5 @ Bet365 (55.6%) | ⭐⭐⭐⭐ | Neither side can afford to play it safe, which points towards an open and attacking game. Chelsea’s matches in this competition have already followed that pattern, with all three of their away fixtures producing at least three goals, and eight of their last 11 games in all competitions finishing with more than 2.5 goals. |
| Scott McTominay & Joao Pedro to score – Yes | 9/1 @ Bet365 (10.0%) | ⭐⭐⭐ | If the game opens up as expected, backing two goalscorers could be the smart angle. Scott McTominay has a habit of delivering when it matters, as shown during last season’s title run, and he has four goals in his last six outings. For Chelsea, Joao Pedro has emerged as Rosenior’s first choice up front and comes into this match in form after scoring in successive starts against Crystal Palace and Brentford. With both players carrying confidence in front of goal, the 9/1 double makes plenty of appeal. |
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Odds correct at the time of writing. Please gamble responsibly.
How both teams go into Napoli vs Chelsea
It has been a bruising spell for Conte’s champions, capped by a heavy 3-0 defeat away to Juventus that left them nine points adrift of Serie A leaders Inter. That loss came on the back of a frustrating draw with ten-man Copenhagen in Europe, where they failed to make their advantage count and were held after conceding an equaliser in Denmark.
Those dropped points leave the Italian side outside the top 24 on goal difference, though qualification remains within reach with a win at home. Confidence can be drawn from their strong European record in Naples and a solid history against English opposition, including a memorable home victory over this week’s visitors earlier in the last decade.

The visitors head into the tie in strong form after a convincing 3-1 win over Crystal Palace, their best display under Liam Rosenior, and have now won three straight matches in all competitions. That momentum will be tested by a poor record in Italy and a long winless run away from home in the Champions League. With qualification positions tightly packed and little margin for error, Chelsea know that anything less than victory could leave their fate out of their hands.
Napoli team news
Alex Meret could make his first Champions League appearance since March 2024 as Vanja Milinkovic Savic is a doubt, while injuries have ruled out Kevin De Bruyne, Frank Anguissa, Billy Gilmour, Matteo Politano, David Neres and Amir Rrahmani, and winter arrival Giovane is unavailable due to eligibility.
Chelsea team news
Cole Palmer is unlikely to start after missing the win at Palace with a thigh issue, and several other players, including Levi Colwill, Tosin Adarabioyo, Dario Essugo, Romeo Lavia and Filip Jorgensen, are unavailable or still recovering.
Season Form & Standings
| Team | Pos | P | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| Chelsea | 8 | 7 | 4 | 1 | 2 | 14 | 8 | +6 | 13 |
| Napoli | 25 | 7 | 2 | 2 | 3 | 7 | 12 | -5 | 8 |
Head-to-Head: Last 6 Meetings
This will be the first competitive clash between Napoli and Chelsea, with no prior meetings in European competition or otherwise. History is there to be written in Naples.
| Date | Score | Competition |
|---|---|---|
| N/A | No previous meetings | UEFA Champions League |
Final Thoughts
This could well be an open, high-scoring contest. Both teams need a win here and the best bet on the card for punters looks to be Over 2.5 goals at a very backable 4/5 with most bookmakers.
Odds correct at the time of writing. Please gamble responsibly.
