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Squawka / News / Mainz 05 vs Hoffenheim: predictions, stats, tips & odds

Mainz 05 vs Hoffenheim: predictions, stats, tips & odds

Mainz 05 host Hoffenheim at the OPEL ARENA on 21 November in a Bundesliga clash that sees the hosts desperate to halt their slide against a Hoffenheim side that have found their scoring touch this season.

The 19:30 kick-off brings together two teams with plenty of recent history and contrasting fortunes in 2025/26: Mainz languish near the bottom, while Hoffenheim sit firmly in the top six. Can Mainz rely on their solid head-to-head record, or will Hoffenheim’s firepower prove decisive?

Best Bets & Predictions

Based on season-long attacking trends and recent head-to-head results, here are our top betting recommendations for this match. We’re particularly confident in “Both Teams To Score – Yes” due to both sides’ defensive vulnerabilities and Hoffenheim’s attacking efficiency.

Our PredictionOdds & BookmakerConfidenceWhy We’re Backing It
Both Teams To Score – YesBet365 and 1/2
(66.7%)
⭐⭐⭐⭐Backing because Mainz have conceded in every match, Hoffenheim score freely (2.1 goals/game).
Hoffenheim to WinBetfair and 13/8
(38.5%)
⭐⭐⭐Value here due to Hoffenheim’s double the goals of Mainz and stronger away form.

Odds correct at the time of writing. Please gamble responsibly.

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Season Form & Standings

Mainz 05 are struggling in 17th, with just one win from ten games, while Hoffenheim have impressed in attack and sit sixth with a top-half record. The gulf in both goals scored and defensive reliability is clear.

TeamPosPWDLGFGAGDPts
Hoffenheim6106132116+519
Mainz 0517101271018-85

Potential Match-Winners

Neither side boasts a player among the Bundesliga’s top scorers, but the attacking output still offers interest. For Hoffenheim, Andrej Kramarić has been central to their forward play, with the team recording 25 big chances created and 21 goals from 10 matches (2.1 goals per game). Hoffenheim’s accuracy is strong—shot accuracy of 51.6%—and their attacking unit has produced significantly more shots on target (50) than Mainz (28). For Mainz, the goals are more evenly spread but their xG (12.2) versus actual goals (10) underlines a need for sharper finishing. Expect set-piece threats, with Mainz having netted three penalties, but their lack of a clinical edge has hurt them.


 

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Head-to-head: Last 6 Meetings

Mainz 05 have traditionally held the upper hand in this fixture, winning eight of the last sixteen meetings, though Hoffenheim have closed the gap in recent seasons. Here’s how the most recent meetings have played out:

DateScoreCompetition
12/04/25Hoffenheim 2-0 Mainz 05Bundesliga
01/12/24Mainz 05 2-0 HoffenheimBundesliga
13/04/24Mainz 05 4-1 HoffenheimBundesliga
26/11/23Hoffenheim 1-1 Mainz 05Bundesliga
04/03/23Mainz 05 1-0 HoffenheimBundesliga
10/09/22Hoffenheim 4-1 Mainz 05Bundesliga

Conclusion

Will Mainz’s strong historical record count for anything against a Hoffenheim side firing on all cylinders? With Mainz conceding nearly two goals per game and Hoffenheim producing chances at pace, the edge looks to be with the visitors. Our value pick remains Both Teams To Score – Yes at 1/2 (66.7%)—a selection that aligns with the attacking trends and defensive frailties on show.

Odds correct at the time of writing. Please gamble responsibly.

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