Home » NFL News » Seahawks vs Cardinals Prediction, Picks & Odds

Seahawks vs Cardinals Prediction, Picks & Odds

Seattle Seahawks vs Arizona Cardinals prediction, picks and odds for Week 2 of the 2026 NFL season

Our Seahawks vs Cardinals prediction gives Arizona the edge in a divisional meeting of unbeaten sides. Squawka Signal’s live read updates on this page through the week.

The Seattle Seahawks won 13-10 at New England on three interceptions and 285 yards. The Arizona Cardinals ran 71 plays against the Chargers and won by 12. Turnover luck tends to even out; snap counts tend not to.

Week 1 · Editorial pick

Seahawks vs Cardinals: our editor’s props

Two editorial calls to sit alongside the live Signal numbers on this page.

Seahawks AT Cardinals

Our props

Player propTrey McBride 60+ receiving yardsMcBride caught nine for 95 and a touchdown against the Chargers. Seattle conceded 178 passing yards to New England while intercepting three.
★★★★confidence
Player propJaxon Smith-Njigba 70+ receiving yardsSmith-Njigba took 122 of Seattle’s 200 passing yards in Week 1. Arizona conceded 209 to Justin Herbert.
★★★★★confidence

An editorial call, not a Signal model output. 19+ (18+ in AB, MB and QC). Please play responsibly.

Seahawks vs Cardinals: 2026 form so far

Two winners, and a table that says one of them was rather more convincing.

2026 season to dateSeahawksCardinals
Record1-01-0
Points for1326
Points against1014
Point differential+3+12
Total yards285393
Yards per play5.95.5
Turnovers00
Third-down offence18.2%42.9%
Red-zone offence0.0%40.0%
Sacks recorded33
Opponent passer rating54.983.7

Arizona did not turn the ball over once. Seattle converted 18.2% of third downs and scored nothing from their red-zone visits.

Seahawks vs Cardinals injury report and team news

Trey McBride caught nine for 95 and a touchdown against the Chargers. Jacoby Brissett completed 27 of 37 without an interception.

This section updates as soon as the Out, Doubtful and Questionable tags land.

The matchup that settles it: Trey McBride against a secondary that took three

McBride is Arizona’s most reliable target and faces a Seattle defence that intercepted three passes at New England. Brissett has thrown none.

Jaxon Smith-Njigba carried Seattle’s passing game almost alone, with 122 of their 200 yards. Arizona conceded 209 to Justin Herbert.

Possession is the theme. Arizona kept the ball for 37:31 and Seattle ran 48 plays, which will not sustain a road win in the desert.

Players to watch

  • Jaxon Smith-Njigba (SEA, WR): Eight catches for 122 yards and a touchdown in the opener.
  • Drew Lock (SEA, QB): 187 yards and a touchdown at a 113.3 rating against New England.
  • Trey McBride (ARI, TE): Nine catches for 95 yards and a score against the Chargers.
  • Jacoby Brissett (ARI, QB): 27 of 37 for 277 yards without an interception.

How to watch Seahawks vs Cardinals

The game kicks off at 4:25 PM ET on Sunday, September 20, which is 3:25 PM CT and 1:25 PM PT. CTV has the regional broadcast and RDS the French-language call, and DAZN carries every game of the season. Squawka may earn a commission if you subscribe through that link.

DetailSeahawks vs Cardinals
DateSunday, September 20, 2026
Kickoff4:25 PM ET / 3:25 PM CT / 1:25 PM PT
VenueState Farm Stadium, Glendale, AZ
TVCTV (regional) / RDS (French)
Live streamDAZN (NFL Game Pass) / CTV.ca
WeekWeek 2, 2026 NFL season

Seahawks vs Cardinals prediction and score projection

Our Seahawks vs Cardinals prediction is an Arizona win, 23-20. The Cardinals dictate tempo and Seattle’s offence has not yet shown enough.

Signal’s live number updates on this page through the week.

Every fixture in the round is covered across our NFL hub, and Signal rates every Week 2 game the same way. Compare the AFC Championship odds and NFC Championship odds as the season develops, and our guide to watching the NFL in Canada covers every window.

Seahawks vs Cardinals FAQ

Who is favoured to win, the Seahawks or the Cardinals?

Arizona, at home. Both won in Week 1, though the Cardinals did so without turning the ball over.

What time is Seahawks vs Cardinals in Canada?

4:25 PM ET on Sunday, September 20, which is 3:25 PM CT and 1:25 PM PT.

What channel is Seahawks vs Cardinals on in Canada?

CTV has the regional broadcast and RDS the French. DAZN carries it as a stream.

How did each side do in Week 1?

Seattle beat New England 13-10. Arizona beat the Chargers 26-14.

19+ (18+ in AB, MB and QC) | Please play responsibly | ConnexOntario: 1-866-531-2600 (ON) | Signal probabilities approximate at time of writing and subject to change