Our Seahawks vs Cardinals prediction is a division game between two 1-0 teams, and the closer call of the late window. Squawka Signal’s live read on this game, including where the value sits, updates on this page through the week.
The Seattle Seahawks won 13-10 on three interceptions and almost nothing else. The Arizona Cardinals beat the Chargers 26-14 while holding the ball for 37 and a half minutes. Consequently one of these wins looks far more repeatable than the other.
Seattle Seahawks @ Arizona Cardinals
Seattle SeahawksSquawka73%Market68%▲ Value
Arizona CardinalsSquawka27%Market32%▼ Slight laySquawka Signal is our model’s read against devigged market prices, updated after every result — not betting advice. How the NFL Signal works. 21+. Play responsibly. Full T&Cs & geo-restrictions apply: Kalshi, Polymarket, ProphetX.
Seahawks vs Cardinals: our editor’s props
Two editorial calls to sit alongside the live Signal numbers on this page.
AT Our props
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Seahawks vs Cardinals: 2026 form so far
Both won, and the tables show why only one of them looks convincing. Seattle scored 13 points and won; Arizona controlled everything and won by 12.
| 2026 season to date | Seahawks | Cardinals |
|---|---|---|
| Record | 1-0 | 1-0 |
| Points for | 13 | 26 |
| Points against | 10 | 14 |
| Point differential | +3 | +12 |
| Total yards | 285 | 393 |
| Yards per play | 5.9 | 5.5 |
| Turnovers | 0 | 0 |
| Third-down offense | 18.2% | 42.9% |
| Red-zone offense | 0.0% | 40.0% |
| Sacks recorded | 3 | 3 |
| Opponent passer rating | 54.9 | 83.7 |
Seattle converted 18.2% of third downs and did not score in the red zone from two trips. Arizona, by contrast, ran 34 times and turned the ball over not once.
Seahawks vs Cardinals injury report and team news
Drew Lock took 22 of Seattle’s 24 pass attempts in the opener, throwing for 187 at a 113.3 rating. Sam Darnold attempted two.
This section updates as soon as the Out, Doubtful and Questionable tags land.
Seattle SeahawksArizona CardinalsWhere Seahawks vs Cardinals is decided
Seattle’s three interceptions decided their opener. Jacoby Brissett did not throw one against the Chargers, completing 73% at a 103.1 rating.
Arizona held the ball for 37:31 and ran 34 times. Seattle managed 48 plays in total, which is not enough against a side that keeps possession.
Nevertheless Seattle’s defense recorded three sacks alongside the interceptions. Similarly Arizona reached the red zone five times and converted only two.
Players to watch
- Jaxon Smith-Njigba (SEA, WR): Eight catches for 122 yards and a touchdown in the opener.
- Drew Lock (SEA, QB): 187 yards and a touchdown at a 113.3 rating against New England.
- Trey McBride (ARI, TE): Nine catches for 95 yards and a score against the Chargers.
- Jacoby Brissett (ARI, QB): 27 of 37 for 277 yards without an interception.
How to watch Seahawks vs Cardinals
The game kicks off at 4:25 PM ET on Sunday, September 20 at State Farm Stadium in Glendale. FOX carries it. This is one of the afternoon’s later kickoffs.
| Detail | Seahawks vs Cardinals |
|---|---|
| Date | Sunday, September 20, 2026 |
| Kickoff | 4:25 PM ET / 3:25 PM CT / 1:25 PM PT |
| Venue | State Farm Stadium, Glendale, AZ |
| TV | FOX |
| Live stream | NFL Game Pass (DAZN) |
| Week | Week 2, 2026 NFL season |
Seahawks vs Cardinals prediction and score projection
Our Seahawks vs Cardinals prediction is an Arizona win, 24-17. Home field and the ability to keep the ball settle it; Seattle need the turnovers again.
Ultimately the live win probability updates on this page through the week.
Every fixture in the round is covered across our NFL hub, and Signal rates every Week 2 game the same way.
Seahawks vs Cardinals FAQ
Arizona, at home. Both are 1-0, but the Cardinals held the ball for 37 minutes in their opener while Seattle scored 13 points.
4:25 PM ET on Sunday, September 20, which is 3:25 PM CT and 1:25 PM PT.
FOX has the game in the United States.
Drew Lock took the vast majority of the snaps in Week 1, throwing for 187 yards. Sam Darnold attempted two passes.
21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change