Arizona have conceded 23 touchdowns and allow a 116.5 opponent passer rating. Both are the worst figures in the NFL, and our Broncos vs Cardinals prediction finds them hosting a 4-2 team.
The Arizona Cardinals are 2-4 at -52. The Denver Broncos allow a 73.1 opponent rating, second only to Minnesota, and are 4-2 despite being outscored by 11 — the oddity of their season.
Broncos vs Cardinals: our editor’s props
Two calls from our editor, to read next to Signal’s live numbers.
AT 
Our props
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Broncos vs Cardinals: 2026 form so far
The league’s worst pass defense against one of its best. The table sets each attack against what the opposite defense has actually allowed.
Broncos attack against the Cardinals defense
| Per game | Broncos offense | Cardinals allow |
|---|---|---|
| Passing yards | 168.0 | 229.7 |
| Rushing yards | 84.2 | 120.8 |
| Yards per carry | 3.4 | 4.4 |
| Passer rating | 79.4 | 116.5 |
| Touchdowns | 2.0 | 3.8 |
| Third-down conversion | 31.6% | 41.8% |
| Red-zone conversion | 61.1% | 71.4% |
| Sacks conceded / recorded | 1.3 | 2.3 |
Cardinals attack against the Broncos defense
| Per game | Cardinals offense | Broncos allow |
|---|---|---|
| Passing yards | 211.0 | 208.5 |
| Rushing yards | 96.3 | 139.8 |
| Yards per carry | 3.7 | 4.7 |
| Passer rating | 83.6 | 73.1 |
| Touchdowns | 2.0 | 2.2 |
| Third-down conversion | 39.3% | 44.4% |
| Red-zone conversion | 47.8% | 52.9% |
| Sacks conceded / recorded | 2.0 | 3.0 |
Denver are 4-2 and have been outscored by 11. That is the sort of record a defense drags a team to, and the numbers say exactly that.
Broncos vs Cardinals quarterback matchup
Bo Nix has six touchdown passes to three interceptions at 79.4 and threw for 107 yards last week. Jacoby Brissett has nine to six at 83.4.
| Team | Quarterback | Last game | Season to date |
|---|---|---|---|
| Broncos | Bo Nix | 17/27, 107 yds, 0 TD, 0 INT, 71.1 rtg | 114/189, 1049 yds, 6 TD, 3 INT, 79.4 rtg (6 games) |
| Cardinals | Jacoby Brissett | 24/35, 218 yds, 0 TD, 1 INT, 73.3 rtg | 156/234, 1328 yds, 9 TD, 6 INT, 83.4 rtg (6 games) |
Broncos vs Cardinals injury report and team news
Arizona have conceded 23 touchdowns in six games, more than any team in the NFL.
Arizona allow a 116.5 opponent passer rating, also the worst figure in the league.
Denver allow a 73.1 opponent rating, second only to Minnesota’s 62.9.
The worst pass defense in the league, and one of the best
Arizona concede a 116.5 opponent rating and 23 touchdowns, both the worst marks in football, and let opponents finish 71.4% of their red-zone trips.
Denver sit at the other end at 73.1, and have 18 sacks to go with it. On defense they are among the best three teams in the league.
What stops this being a rout is Denver’s own attack. They run for 3.44 a carry and convert 31.6% on third down, both among the three worst marks in the NFL, and have thrown for 1,008 yards.
Players to watch
- Bo Nix (DEN, QB): Six touchdown passes at a 79.4 rating.
- RJ Harvey (DEN, RB): Shares a backfield averaging 3.44 a carry.
- Jacoby Brissett (ARI, QB): 1,328 passing yards and nine touchdowns at 83.4.
- Trey McBride (ARI, TE): Arizona’s leading target since the Harrison trade.
How to watch Broncos vs Cardinals
Kickoff is 4:05 PM ET on Sunday, October 25 at State Farm Stadium, which is 3:05 PM CT and 1:05 PM PT. CBS has the regional broadcast.
| Detail | Broncos vs Cardinals |
|---|---|
| Date | Sunday, October 25, 2026 |
| Kickoff | 4:05 PM ET / 3:05 PM CT / 1:05 PM PT |
| Venue | State Farm Stadium, Glendale, AZ |
| TV | CBS |
| Live stream | NFL+ / Paramount+ |
| Week | Week 7, 2026 NFL season |
Broncos vs Cardinals prediction and score projection
Denver win 26-17. Arizona concede more touchdowns than anyone and Denver’s defense is the second-best in the league by rating, which covers for an attack that does little.
The live line and our projected margin both update through the week.
Every Week 7 game, previewed
| Kickoff (ET) | Game | Our prediction | Preview |
|---|---|---|---|
| Thu 8:15 PM | Patriots @ Bears | Patriots 24-21 | Read |
| Sun 9:30 AM | Steelers @ Saints | Steelers 27-20 | Read |
| Sun 1:00 PM | Bengals @ Ravens | Ravens 27-23 | Read |
| Sun 1:00 PM | Browns @ Titans | Browns 20-16 | Read |
| Sun 1:00 PM | Colts @ Vikings | Vikings 27-13 | Read |
| Sun 1:00 PM | Dolphins @ Jets | Jets 20-16 | Read |
| Sun 1:00 PM | Giants @ Texans | Texans 23-17 | Read |
| Sun 1:00 PM | 49ers @ Falcons | 49ers 30-20 | Read |
| Sun 1:00 PM | Buccaneers @ Panthers | Panthers 24-20 | Read |
| Sun 4:05 PM | Broncos @ Cardinals | Broncos 26-17 | You are here |
| Sun 4:25 PM | Packers @ Lions | Lions 27-24 | Read |
| Sun 4:25 PM | Rams @ Raiders | Rams 27-23 | Read |
| Sun 8:20 PM | Chiefs @ Seahawks | Chiefs 24-23 | Read |
| Mon 8:15 PM | Cowboys @ Eagles | Eagles 23-20 | Read |
The full NFL picks page and the NFL odds page carry the rest of the card. The outright markets are priced in the Super Bowl market. For the player side of this game, see prop markets for this game.
Broncos vs Cardinals FAQ
Denver. Our Signal model has the Broncos as clear favorites, with the live number in the Signal card on this page. Denver are 4-2; Arizona are 2-4 at -52.
4:05 PM ET on Sunday, October 25 at State Farm Stadium, which is 3:05 PM CT and 1:05 PM PT.
Arizona, with 23 in six games.
They are 4-2 but have been outscored by 11. The defense has carried them: a 73.1 opponent rating, second-best in the NFL.
21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change