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Roma vs Real Madrid: Predictions, Picks, Odds & Lineups

Roma vs Real Madrid predicted formations

Roma host Real Madrid at Stadio Olimpico on Wednesday, October 14 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).

Roma have no fresh fitness concerns to report, with Bryan Cristante, Paulo Dybala, and Donyell Malen all expected to feature after playing significant minutes in the opening round. Real Madrid are similarly unaffected, with Kylian Mbappé, Federico Valverde, and Brahim Díaz the headline names likely to lead the visitors’ attack.

US viewers can watch Roma vs Real Madrid on Paramount+.

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Match outcome · who wins
RomaRoma29%mkt 25%Value +4
DrawDraw23%mkt 23%
Real MadridReal Madrid49%mkt 53%Our pick

Roma vs Real Madrid: Best Bets & Predictions

Signal has Real Madrid at 49% — no edge over the market on the result. The market’s soft on Roma (+4) — our value angle.

In lineno standout edge on the result

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The tips · best bets
MarketMkt %Signal %Read
Correct ScoreRoma 1-2 Real MadridMbappé and Valverde both scored in Real Madrid's last outing, enough firepower to edge a tight game in Rome while Roma's own threat from Cristante keeps it close at 1-2.
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9%
Model read
Both Teams to ScoreBoth teams to scoreRoma's Cristante scored in the draw at Fenerbahce and Real Madrid found the net twice against Inter Milan, pointing to goals at both ends again.
69%
67%
In line
Over / Under 2.5Over 2.5Real Madrid's last match produced 3 goals and Roma's draw also finished with goals shared between both sides, supporting another game that crosses over 2.5.
70%
67%
Priced in
Anytime ScorerKylian MbappéMbappé scored and registered 4 shots, all 4 on target, in Real Madrid's last game, the clearest sign of where their goals come from.
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79%
Model read
Signal edge callsRecord building · settles at full-time

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Season Form & Standings

Roma have taken 1 point from their opening fixture, a 1-1 draw at Fenerbahce, while Real Madrid sit on 3 points after a 2-1 win over Inter Milan.

Champions League

TeamPosGPWDLGFGAGDPts
Real Madrid14110021+13
Roma1710101101
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Team News Predicted

Roma vs Real Madrid Predicted Lineups

Predicted XI — updated for the latest team news.

Roma

3-4-2-1
M. Svilar
Mario Hermoso
E. Ndicka
G. Mancini
Wesley
B. Cristante
M. Kone
D. Rensch
M. Soule
P. Dybala
D. Malen

Real Madrid

4-2-3-1
T. Courtois
Marc Cucurella
Dean Huijsen
I. Konate
D. Dumfries
F. Valverde
T. Alexander-Arnold
Vinicius Junior
J. Bellingham
B. Diaz
K. Mbappe
    Squawka · Team News

    Potential Match-Winners

    • Bryan Cristante (Roma): Cristante scored in Roma’s opening draw and played the full 90 minutes, giving Roma a reliable goal threat from midfield.
    • Paulo Dybala (Roma): Dybala put 2 of his 2 shots on target against Fenerbahce, confirming his status as Roma’s main source of quality in the final third.
    • Kylian Mbappé (Real Madrid): Mbappé was Real Madrid’s biggest attacking outlet with 4 shots, all 4 on target, in the win over Inter Milan.

    Recent Form

    Roma: D

    • 2026-09-10: Fenerbahce 1-1 Roma (D, away)

    Roma’s only game so far produced a 1-1 draw away at Fenerbahce, with Bryan Cristante among the scorers.

    Real Madrid: W

    • 2026-09-08: Real Madrid 2-1 Inter Milan (W, home)

    Real Madrid opened with a 2-1 win over Inter Milan, Kylian Mbappé and Federico Valverde both getting on the scoresheet.

    Roma vs Real Madrid Prediction

    This looks tight rather than one-sided. Roma sit on 1 point after their draw at Fenerbahce and will make life difficult for a Real Madrid side on 3 points, but Real Madrid’s edge in front of goal, shown by Mbappé’s 4 shots on target against Inter Milan, should be enough to see them home 1-2 in a game that produces goals at both ends.