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Atletico Madrid vs Manchester United: Predictions, Picks, Odds & Lineups

Atletico Madrid vs Manchester United predicted formations

Atletico Madrid host Manchester United at Estadio Wanda Metropolitano on Tuesday, October 13 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).

Neither side has an injury or suspension to work around ahead of kickoff, with both squads expected to be close to full strength. Atletico’s threat starts with Marcos Llorente, who scored their goal in the defeat to Liverpool, and Julián Alvarez, who fired three shots on target and set up a goal in that same game. Manchester United’s team news centers on the firepower that ran riot against Sabah, where Bruno Fernandes, Matheus Cunha, Lisandro Martínez and Benjamin Šeško all found the net.

Atletico arrive off a 2-1 loss away to Liverpool, a result that leaves them with 0 points and a -1 goal difference from their opening match, while Manchester United head into this full of confidence after putting 4 goals past Sabah, a result worth 3 points and a +4 goal difference of their own. Home advantage at the Riyadh Air Metropolitano gives Atletico a platform to respond, but United’s attacking output from their opener suggests goals should flow at both ends rather than this settling into a stalemate.

US viewers can watch Atletico Madrid vs Manchester United on Paramount+.

Squawka Signal
Where are you?
Match outcome · who wins
Atletico MadridAtletico Madrid47%mkt 46%Our pick
DrawDraw23%mkt 24%
Manchester UnitedManchester United30%mkt 30%

Atletico Madrid vs Manchester United: Best Bets & Predictions

Signal has Atletico Madrid at 47% — no edge over the market on the result.

In lineno standout edge on the result

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The tips · best bets
MarketMkt %Signal %Read
Correct ScoreAtletico Madrid 2-1 Manchester UnitedAtletico scored through Llorente in their last match while Manchester United's 4-0 win over Sabah showed they don't go quiet at the other end, pointing to a tight 2-1 finish.
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9%
Model read
Both Teams to ScoreBoth teams to scoreAtletico found the net via Llorente against Liverpool and Manchester United scored four times past Sabah, so neither side looks like keeping a clean sheet here.
68%
67%
In line
Over / Under 2.5Over 2.5Manchester United's 4-0 win and Atletico's 2-1 defeat both produced goals at a rate that points toward this one going over 2.5 again.
66%
66%
In line
Anytime ScorerMarcos Llorente to score anytimeMarcos Llorente scored Atletico's goal in the defeat to Liverpool and should be pushed forward again with the aim of adding to that tally in front of his own fans.
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Model read
Signal edge callsRecord building · settles at full-time

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Season Form & Standings

Manchester United sit on 3 points with a +4 goal difference after their opening match, while Atletico Madrid have 0 points and a -1 goal difference from theirs.

Champions League

TeamPosGPWDLGFGAGDPts
Manchester United4110040+43
Atletico Madrid25100112-10
Shop the matchAtletico Madrid v Manchester UnitedOfficial kits via Fanatics
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Team News Predicted

Atletico Madrid vs Manchester United Predicted Lineups

Predicted XI — updated for the latest team news.

Atletico Madrid

3-5-2
J. Oblak
D. Hancko
C. Romero
Marc Pubill
G. Simeone
Alex Baena
Koke
Pablo Barrios
Marcos Llorente
J. Alvarez
Lee Kang-In

Manchester United

4-2-3-1
S. Lammens
P. Dorgu
L. Martinez
L. Yoro
N. Mazraoui
K. Mainoo
Y. Tielemans
Matheus Cunha
Bruno Fernandes
B. Mbeumo
B. Sesko
    Squawka · Team News

    Potential Match-Winners

    • Marcos Llorente (Atletico Madrid): The midfielder scored Atletico’s goal in the defeat to Liverpool, converting his sole shot on target, and will look to add to that return back on home turf.
    • Julián Alvarez (Atletico Madrid): Julián Alvarez didn’t get on the scoresheet against Liverpool but fired 3 shots on target, created a chance and claimed an assist, underlining his central role in everything Atletico create.
    • Bruno Fernandes (Manchester United): Bruno Fernandes scored and created 4 chances in the win over Sabah, and his movement between the lines will test an Atletico midfield still searching for its best shape.

    Recent Form

    Atletico Madrid: L

    • 2026-09-09: Liverpool 2-1 Atletico Madrid (L, away)

    Atletico Madrid’s last outing ended in a 2-1 loss away to Liverpool on September 9, with Marcos Llorente scoring their goal.

    Manchester United: W

    • 2026-09-10: Manchester United 4-0 Sabah (W, home)

    Manchester United’s last outing was a 4-0 win at home to Sabah on September 10, with Bruno Fernandes, Matheus Cunha, Lisandro Martínez and Benjamin Šeško all on the scoresheet.

    Atletico Madrid vs Manchester United Prediction

    Atletico Madrid, winless and without a point after their opener, look for a response at the Riyadh Air Metropolitano, and Marcos Llorente’s eye for goal alongside Julián Alvarez’s movement give them the edge in a game that should finish 2-1 to the home side. Manchester United will carry their scoring form into Madrid and should find the net themselves, but Atletico edge this 2-1.