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Giants vs Rams Prediction, Picks & Odds: Week 2

New York Giants vs Los Angeles Rams prediction, picks and odds for Week 2 of the 2026 NFL season

Our Giants vs Rams prediction closes Week 2 on Monday night, between a team that could do no wrong in its opener and one that scored seven points. Squawka Signal’s live read on this game, including where the value sits, updates on this page through the week.

The New York Giants beat Dallas 28-20 converting nine of eleven third downs. The Los Angeles Rams lost 27-7 to San Francisco in Melbourne. Consequently the form line points one way, even with the Rams at home.

Squawka Signal · Model vs market

New York Giants @ Los Angeles Rams

Week 2 · Mon Sep 21, 8:15 PM ET. Our Signal model makes the Los Angeles Rams favorites by about 6 points, a 71% win probability.

NYGNew York GiantsSquawka29%Market24%▲ Value
LALos Angeles RamsSquawka71%Market76%▼ Slight lay
Projected lineLos Angeles Rams -6
ValueNew York Giants — model 29% vs market 24%

Squawka Signal is our model’s read against devigged market prices, updated after every result — not betting advice. How the NFL Signal works. 21+. Play responsibly. Full T&Cs & geo-restrictions apply: Kalshi, Polymarket, ProphetX.

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Week 1 · Editorial pick

Giants vs Rams: our editor’s props

Two editorial calls to sit alongside the live Signal numbers on this page.

Giants AT Rams

Our props

Player propJaxson Dart 2+ passing touchdownsDart threw three at a 134.2 rating against Dallas, the highest of the weekend. The Rams did intercept Brock Purdy once, so this is not free.
★★★★★confidence
Player propLos Angeles under 21.5 pointsThe Rams scored seven against San Francisco on 22.2% third-down conversion. The Giants conceded 20 to Dallas while forcing an interception.
★★★★confidence

An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.

Giants vs Rams: 2026 form so far

One team converted 81.8% of its third downs; the other managed 22.2% and scored seven points. The tables are as far apart as the results.

2026 season to dateGiantsRams
Record1-00-1
Points for287
Points against2027
Point differential+8-20
Total yards394290
Yards per play5.85.1
Turnovers12
Third-down offense81.8%22.2%
Red-zone offense100.0%33.3%
Sacks recorded00
Opponent passer rating84.8105.6

The Giants went four from four in the red zone and held the ball for 36:40. The Rams turned it over twice and did not throw a touchdown.

Giants vs Rams injury report and team news

Jaxson Dart completed 23 of 29 for three touchdowns against Dallas. Isaiah Likely caught all eight of his targets for 78 yards and two scores.

This section updates as soon as the Out, Doubtful and Questionable tags land.

Injury report · Week 2Official game-status report — updates through the week
NYGNew York Giants
No game-status designations filed yet.
LALos Angeles Rams
No game-status designations filed yet.

Where Giants vs Rams is decided

The Rams scored seven points in Melbourne and Matthew Stafford threw for 155 without a touchdown. That is the number this game turns on.

New York’s third-down conversion will not stay at 81.8%, but the red-zone efficiency was just as good and the possession advantage was 13 minutes.

Los Angeles are at home and were playing on the other side of the world a fortnight earlier. Nevertheless they were out-gained by 89 yards and lost by 20.

Players to watch

  • Jaxson Dart (NYG, QB): Three touchdown passes at a 134.2 rating against Dallas.
  • Isaiah Likely (NYG, TE): Eight catches from eight targets for 78 yards and two scores.
  • Puka Nacua (LA, WR): Five catches for 74 yards in a game the Rams lost 27-7.
  • Matthew Stafford (LA, QB): 155 yards, no touchdowns and an interception in Melbourne.

How to watch Giants vs Rams

The game kicks off at 8:15 PM ET on Monday, September 21 at SoFi Stadium in Inglewood. ABC and ESPN carry it. Additionally it is the only game of the night.

DetailGiants vs Rams
DateMonday, September 21, 2026
Kickoff8:15 PM ET / 7:15 PM CT / 5:15 PM PT
VenueSoFi Stadium, Inglewood, CA
TVABC/ESPN
Live streamNFL Game Pass (DAZN)
WeekWeek 2, 2026 NFL season

Giants vs Rams prediction and score projection

Our Giants vs Rams prediction is a New York win, 24-20. The Rams have home field and a week to recover, but they have shown nothing yet.

Ultimately the live win probability updates on this page through the week.

Every fixture in the round is covered across our NFL hub, and Signal rates every Week 2 game the same way.

Giants vs Rams FAQ

Who is favored to win, the Giants or the Rams?

The Giants, despite playing away. New York are 1-0 and converted nine of eleven third downs; the Rams scored seven points in their opener.

What time is Giants vs Rams?

8:15 PM ET on Monday, September 21, which is 7:15 PM CT and 5:15 PM PT.

What channel is Giants vs Rams on?

ABC and ESPN have the game in the United States.

How did each team do in Week 1?

The Giants beat Dallas 28-20. The Rams lost 27-7 to San Francisco in Melbourne.

21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change