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    NFL Predictions 2026: Squawka Signal’s AI Picks

    Squawka Signal is our in-house NFL model, and this is its call on every game — a winner, a win probability and the projected spread for each fixture, refreshed every week. It is the same engine behind our power rankings and Super Bowl odds, pointed at the week ahead.

    Every pick is locked before kickoff and graded afterwards, straight-up and against the spread, so the record below is a real one that builds through the season — not a number we can tidy up after the fact.

    Squawka Signal · NFL AI Predictor

    Week 1 NFL Predictions

    The Squawka Signal model’s call on every game this week — the winner, a win probability and the projected spread — each linked to the full preview, with a running record of how the calls have gone.

    New for 2026 — the record starts this week and builds through the season.
    Week 1
    MatchSignal pickWin %
    NE New England Patriots @ Seattle Seahawks SEAWed Sep 9, 8:20pm ET
    Seattle Seahawks to winSEA -2.0
    58%
    Trade KalshiBet bet365
    SF San Francisco 49ers @ Los Angeles Rams LAThu Sep 10, 8:35pm ET
    Los Angeles Rams to winLA -2.7
    60%
    Trade KalshiBet bet365
    CHI Chicago Bears @ Carolina Panthers CARSun Sep 13, 1:00pm ET
    Chicago Bears to winCHI -3.3
    62%
    Trade KalshiBet bet365
    BAL Baltimore Ravens @ Indianapolis Colts INDSun Sep 13, 1:00pm ET
    Baltimore Ravens to winBAL -2.6
    60%
    Trade KalshiBet bet365
    ATL Atlanta Falcons @ Pittsburgh Steelers PITSun Sep 13, 1:00pm ET
    Pittsburgh Steelers to winPIT -4.2
    65%
    Trade KalshiBet bet365
    CLE Cleveland Browns @ Jacksonville Jaguars JACSun Sep 13, 1:00pm ET
    Jacksonville Jaguars to winJAC -10.3
    83%
    Trade KalshiBet bet365
    TB Tampa Bay Buccaneers @ Cincinnati Bengals CINSun Sep 13, 1:00pm ET
    Cincinnati Bengals to winCIN -3.0
    61%
    Trade KalshiBet bet365
    NYJ New York Jets @ Tennessee Titans TENSun Sep 13, 1:00pm ET
    Tennessee Titans to winTEN -0.1
    50%
    Trade KalshiBet bet365
    NO New Orleans Saints @ Detroit Lions DETSun Sep 13, 1:00pm ET
    Detroit Lions to winDET -6.7
    73%
    Trade KalshiBet bet365
    BUF Buffalo Bills @ Houston Texans HOUSun Sep 13, 1:00pm ET
    Buffalo Bills to winBUF -0.7
    53%
    Trade KalshiBet bet365
    ARI Arizona Cardinals @ Los Angeles Chargers LACSun Sep 13, 4:25pm ET
    Los Angeles Chargers to winLAC -8.1
    78%
    Trade KalshiBet bet365
    GB Green Bay Packers @ Minnesota Vikings MINSun Sep 13, 4:25pm ET
    Green Bay Packers to winGB -0.5
    52%
    Trade KalshiBet bet365
    MIA Miami Dolphins @ Las Vegas Raiders LVSun Sep 13, 4:25pm ET
    Miami Dolphins to winMIA -1.9
    57%
    Trade KalshiBet bet365
    WAS Washington Commanders @ Philadelphia Eagles PHISun Sep 13, 4:25pm ET
    Philadelphia Eagles to winPHI -6.5
    73%
    Trade KalshiBet bet365
    DAL Dallas Cowboys @ New York Giants NYGSun Sep 13, 8:20pm ET
    Dallas Cowboys to winDAL -0.3
    51%
    Trade KalshiBet bet365
    DEN Denver Broncos @ Kansas City Chiefs KCMon Sep 14, 8:15pm ET
    Denver Broncos to winDEN -3.4
    63%
    Trade KalshiBet bet365

    The model’s pick locks before kickoff and is graded straight-up and against the spread after the game — that is the running record above. Win probability and the projected line come from tens of thousands of season simulations. A model read, not a betting tip. 21+ where applicable; eligibility varies by US state. How the model works.