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    Como vs RB Leipzig: Predictions, Picks, Odds & Stats

    Como vs RB Leipzig predicted formations

    Como host RB Leipzig on Thursday, September 10 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).

    RB Leipzig travel to Lombardy without three key figures, with the thigh problem ruling out Rocco Reitz, a knee issue sidelining Romulo Cruz and a separate injury keeping Assan Ouedraogo out of contention. Como have nothing to report on the fitness front and go into this one with their options largely intact, though neither club’s teamsheet is confirmed this far out.

    Como vs RB Leipzig: Best Bets & Predictions

    Como aim to open the league phase with a home win as Leipzig arrive without three key men through injury.

    Como to winTop pickComo carry the clear edge on home advantage for this league-phase opener.
    54%win prob.-118 @ bet365
    BTTS – YesLeipzig's thinned-out options, with three players sidelined through injury, should open the game up at both ends.
    64%chance-175 @ bet365
    Over 2.5 goalsThe goal signals here point to an open game rather than a tight, low-scoring one.
    62%chance-163 @ bet365
    Como to win 2-1A narrow home win with goals at both ends fits the team news and the wider market read.
    12%chance750 @ bet365
    Nico Paz to scoreNico Paz scored last weekend against Genoa and, with Como at home to a Leipzig side missing three key figures, is well placed to get on the scoresheet.
    ⭐⭐⭐⭐⭐chanceopening soon @ bet365

    Our approach: we've built these picks around the verified team news and the market's pricing for this fixture, rather than assumptions about a lineup that isn't confirmed yet.

    Back these with bet365Odds shown in American format; your local odds may vary.
    Bet with bet365 → bet365 review

    Odds correct at time of writing and shown in American format for illustration; your local odds may vary. 19+ (18+ in AB/MB/QC). Please play responsibly. ConnexOntario: 1-866-531-2600 (ON).

    Season Form & Standings

    Neither Como nor RB Leipzig have kicked a ball in this season’s league phase yet, both sitting on 0 points from 0 games as the competition proper gets under way for each of them.

    Recent domestic form. Here’s how each side arrives domestically ahead of the European opener:

    Como · Serie A 2026/27

    DWW

    • 04 Sep – Genoa 1–4 Como (A) W
    • 30 Aug – Napoli 1–2 Como (A) W
    • 22 Aug – Udinese 1–1 Como (A) D

    RB Leipzig · Bundesliga 2026/27

    WL

    • 05 Sep – Werder Bremen 3–1 RB Leipzig (A) L
    • 29 Aug – RB Leipzig 3–0 Borussia M'gladbach (H) W

    Potential Match-Winners

    • Nico Paz (Como): Como’s creative hub opened his account against Genoa at the weekend and is the home side’s likeliest source of a goal or an assist.
    • Anastasios Douvikas (Como): Level as Como’s top scorer with two in the opening Serie A rounds, the striker gives them a focal point up front.
    • Ridle Baku (RB Leipzig): Leipzig’s early top scorer with two goals, a direct, driving threat from the right.
    • Christopher Nkunku (RB Leipzig): Back among the creators this season, he supplies the cutting edge in behind.

    Como vs RB Leipzig Prediction

    Como’s home advantage and Leipzig’s threadbare team news tip this towards the hosts, and with goals well backed at both ends, a tight 2-1 fits the market’s mood best. Both clubs open their league-phase campaigns from the same blank state, but Como look the safer starting point on home soil.