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Soccer Predictions & Picks This Week

Squawka’s soccer predictions for the week ahead — confidence-rated picks on the MLS and Liga MX fixtures our previews cover, refreshed as each matchday’s lines drop.

With the World Cup done, MLS and Liga MX are back in action and lead our coverage; Premier League and Champions League picks return when those seasons kick off. The picks below are pulled from our individual match previews, which work through form, head-to-head records, key player availability and the opening lines before settling on a confidence rating. Click any match name to read the full breakdown. Odds are bet365 prices at time of writing; before placing a wager, compare the top US sportsbooks for the best available numbers.

This week’s soccer predictions

This week’s picksMLS & Liga MX12 matches covered
DateCompetitionMatchPickSquawka probabilitybet365 odds
Tue 21 JulLiga MXCruz Azul vs PueblaCruz Azul to Win73%-285 @ bet365
Tue 21 JulLiga MXToluca vs Pumas UNAMToluca to Win61%See bet365
Wed 22 JulMLSInter Miami vs Chicago FireInter Miami to Win52%See bet365
Wed 22 JulMLSFC Cincinnati vs Vancouver WhitecapsVancouver Whitecaps to Win54%-140 @ bet365
Wed 22 JulMLSCharlotte FC vs Atlanta UnitedCharlotte FC to Win53%-145 @ bet365
Wed 22 JulMLSColumbus Crew vs New York City FCColumbus Crew to Win50%-115 @ bet365
Wed 22 JulMLSPhiladelphia Union vs New York Red BullsPhiladelphia Union to Win56%See bet365
Wed 22 JulMLSNew England Revolution vs Toronto FCNew England to Win51%-109 @ bet365
Fri 24 JulLiga MXClub Tijuana vs Club LeónClub Tijuana to Win46%+105 @ bet365
Fri 24 JulLiga MXAtlante FC vs Club AméricaClub América to Win59%-145 @ bet365
Sat 25 JulLiga MXTigres UANL vs Atletico San LuisTigres UANL to Win68%See bet365
Sat 25 JulLiga MXChivas vs FC JuárezChivas to Win61%-159 @ bet365
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Predictions by bet type

Drill into the bet type you’re working with — same week, same matches, filtered to the picks that fit a specific market.

Bet typeWhat we coverPage
Both Teams to ScoreThis week’s BTTS picks across the leagues we cover, with confidence stars and odds.View BTTS predictions
Over / Under 2.5 GoalsGoals-line picks ranked by confidence, with the over/under read for each fixture.View Over 2.5 predictions
Correct ScoreOur cleanest big-price scorelines for the week, normalised to standard home-away order.View Correct Score predictions
Anytime GoalscorerGoalscorer picks with player stats, xG and the matchup angle that supports each tip.View Anytime Goalscorer predictions

Key stats behind our predictions

Before locking in any pick, our team runs a few Squawka stats reads. The table below collects the most useful ones across the four leagues we cover. Use it to sense-check our predictions against the underlying numbers.

CompetitionTop scorersClean sheetsAttacking stats
Premier LeagueViewViewView
Champions LeagueViewViewView
MLSViewViewView
Liga MXViewViewView

Prediction markets

If you prefer prediction-market prices over traditional sportsbooks, these longer-range futures are worth tracking:

How we make our predictions

Every pick on this page starts with data. We pull recent form, head-to-head records, expected-goals numbers, and squad availability from our football database, then cross-reference the opening odds to find bets where the implied probability looks off. The confidence stars are not gut feel — they are derived directly from implied probability: a -285 favorite translates to roughly 74% implied, which earns five stars, while a +155 underdog sits around 39%, earning two. The scale runs from one star (below 33% implied) to five (70%+). Right now that covers MLS and Liga MX, with Premier League and Champions League picks returning when those seasons kick off. Each tip links to the full match preview so you can see the reasoning before you decide.

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