Atlante FC vs Atletico San Luis: Predictions, Picks, Odds & Lineups

Atlante FC host Atletico San Luis at Estadio Azteca on Friday, October 23 (11:00 PM ET / 10:00 PM CT / 8:00 PM PT).

Atlante FC have no fresh team-news issues to navigate at the Azteca, with central midfielder Luis Angel Calzadilla Santillan — three goals and eleven chances created this season — expected to anchor the side alongside striker Jhojan Esmaider Julio Palacios, who leads the squad with four assists from his shots total. Atletico San Luis travel with a similarly clean bill of health, leaning on midfielder Sebastien Salles-Lamonge, whose chances created tally tops both rosters, plus attacking midfielders David Rodriguez Uribe and Rafael Nicolas Llorente Sanz, who have three goals apiece.

This is shaping up as a tight contest rather than an avalanche of goals. Atlante’s defense has been breached three times by Pachuca and twice by Queretaro FC in recent weeks, but they have also shown they can hurt teams going forward, as Monterrey found out. Atletico San Luis arrive having lost their last outing at home to Santos Laguna, and while they have scored freely across their last five matches, their defense has been just as open — a pattern that points to goals at both ends but a narrow finish.

US viewers can watch Atlante FC vs Atletico San Luis on ViX, TUDN or Fox.

Season Form & Standings

This is a Liga MX Apertura fixture with the Liguilla picture still forming, and both sides will see three points as a timely boost to their push for one of the postseason spots.

Liga MX

Potential Match-Winners

• Luis Angel Calzadilla Santillan (Atlante FC): Three goals and eleven chances created mark him out as Atlante’s most productive midfielder this season.
• Jhojan Esmaider Julio Palacios (Atlante FC): The striker has four assists and twenty-two shots to his name, making him the creative spark behind Atlante’s front line.
• Sebastien Salles-Lamonge (Atletico San Luis): His twenty-eight created chances are the most of any player in this match, underlining his influence on San Luis’s attack.

Recent Form

Atlante FC: D L D W L

• 2026-10-10: Queretaro FC 2-0 Atlante FC (L, away)
• 2026-09-25: Atlante FC 4-2 Monterrey (W, home)
• 2026-09-18: Club Puebla 1-1 Atlante FC (D, away)
• 2026-09-11: Atlante FC 0-3 Pachuca (L, home)
• 2026-09-05: Atlas FC 1-1 Atlante FC (D, away)

Atlante’s form reads D, L, D, W, L: a 4-2 win over Monterrey sits alongside a 1-1 draw at Puebla, a 0-3 loss to Pachuca, and a 2-0 defeat at Queretaro FC last time out.

Atletico San Luis: L L W W L

• 2026-10-11: Atletico San Luis 1-2 Santos Laguna (L, home)
• 2026-09-27: Pumas UNAM 2-3 Atletico San Luis (W, away)
• 2026-09-19: Atletico San Luis 3-1 Necaxa (W, home)
• 2026-09-14: Club Leon 2-0 Atletico San Luis (L, away)
• 2026-09-05: Atletico San Luis 0-3 Chivas (L, home)

Atletico San Luis have swung between extremes too, following a 3-1 win over Necaxa and a 2-3 win at Pumas UNAM with a 1-2 home loss to Santos Laguna last time out, sandwiched by earlier defeats of 2-0 at Club Leon and 0-3 to Chivas.

Atlante FC vs Atletico San Luis Prediction

Atlante’s home scoring depth, led by Calzadilla, Palacios and Sarrafiore, should give them the edge in a tightly matched Liga MX Apertura fixture, with San Luis’s own threat from Salles-Lamonge, Rodriguez Uribe and Llorente Sanz ensuring both ends stay involved. Our Signal model has this one finishing 2-1 to Atlante FC.