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USA vs Chile: Prediction, Best Bets & How to Watch

Our USA vs Chile prediction, best bets and odds for Tuesday in St. Louis — game two of four in Mauricio Pochettino’s compressed fall window.

Kick-off at Energizer Park is 8:00 PM ET on Tuesday, September 29. Full US broadcast details are below.

USA vs Chile: Best Bets & Predictions

Shorter than Orlando after a 4-1 win, and a tired-legs game that should still produce goals.

USA to winTop pickThe United States beat Peru 4-1 in Orlando on Saturday and have shortened from -182 to -240. Kalshi has them at 68%.
68%Kalshi-240best price
Over 2.5 goalsFive goals in Orlando, two rotated squads and two coaches using the night to look at players. Tight and controlled is not the likely outcome.
-138best price
USA to win & both teams to scoreA largely changed back line three days on from Orlando is where this gets untidy, and the price rewards a home win that is not a clean sheet.
+225best price

Our approach: same shape as Orlando, shorter odds, and the same read on the goals.

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Where to watch USA vs Chile

USA vs Chile kicks off at 8:00 PM ET / 7:00 PM CT / 5:00 PM PT on Tuesday, September 29, at Energizer Park in St. Louis, Missouri.

In the United States the game is on TNT, truTV and Universo, and streams on HBO Max and Peacock.

USA vs Chile: what’s at stake?

Three days on from Peru, the United States go again in St. Louis with a squad that will look substantially different. That is the point of the window: four games in 11 days against Peru, Chile, Mexico and Canada, with Pochettino spreading minutes and finding out who can handle the step up. He has a contract through 2030 and, for the first time in a while, no tournament immediately breathing down his neck.

Chile arrive having already played Canada in Toronto on Saturday, which makes this their second game of a North American trip and their second against a co-host of a World Cup they did not qualify for. They were last of the ten CONMEBOL nations on 11 points. Whatever this window is for them, it is not a measuring stick.

Team news and talking points

Expect wholesale changes from the side that started in Orlando — Pochettino has said as much, and the schedule makes it unavoidable. Chile face the same problem in reverse, having travelled from Toronto with a squad that was already thin on established internationals. As with the other midweek fixtures in this window, the sportsbook market here is currently thin: a single book is pricing it, and those numbers were last refreshed at the start of September. The window opened against Peru in Orlando on Saturday; our USA vs Peru preview covers that one.

USA vs Chile prediction

The United States should win this and probably win it comfortably, but two rotated teams on short rest rarely produce a clean performance. Expect something ragged that ends up looking straightforward on the scoreboard. Prediction: USA 2-1.

USA vs Chile FAQ

What time is USA vs Chile?

USA vs Chile kicks off at 8:00 PM ET / 7:00 PM CT / 5:00 PM PT on Tuesday, September 29.

What channel is USA vs Chile on in the US?

The game is on TNT, truTV and Universo, and streams on HBO Max and Peacock.

Where is USA vs Chile being played?

USA vs Chile is being played at Energizer Park in St. Louis, Missouri.

Who will win USA vs Chile?

Our prediction is USA 2-1. Our top pick is USA to win at -182.

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