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Borussia Dortmund vs Real Betis: Predictions, Picks, Odds & Lineups

Borussia Dortmund vs Real Betis predicted formations

Borussia Dortmund host Real Betis at Signal-Iduna-Park on Wednesday, November 4 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).

No absences are flagged for either side heading into this one, so both teams should be able to go with their first-choice options. Serhou Guirassy leads the Borussia Dortmund attack with four goals already this season, with Joey Veerman and Felix Nmecha supplying from midfield. Fábio Silva has added 1 assist and 7 shots in just 164 minutes off the bench. Real Betis will lean on Troy Parrott through the centre and Abdessamad Ezzalzouli just behind him, while Marc Bartra remains a constant aerial threat from set pieces at the back.

Dortmund have won 2 of 3 outings, good for 6 points and a +1 goal difference. Betis have won all three of their group games, running up 9 points and a +3 goal difference that marks them as one of the competition’s livelier scoring sides early on. Expect that quality at both ends to tell at Signal Iduna Park: Dortmund’s firepower and Betis’s knack for finding the net themselves point to goals in both directions, with the hosts’ edge at home tipping it their way.

Borussia Dortmund vs Real Betis: Best Bets & Predictions

Guirassy's goals against an unbeaten Betis side at Signal Iduna Park

Borussia DortmundTop pickBetis arrive with 9 points from 3 games, but Dortmund's attacking output, led by Guirassy's 4 goals, gives them the edge at home.
Borussia Dortmund 2-1 Real BetisA 2-1 finish fits a game where Dortmund's attack, led by Guirassy's 4 goals, should have enough to see off a Betis side building a +3 goal difference of their own.
YesBoth sides carry goal threats: Guirassy has 4 for Dortmund, while Betis's front line of Parrott, Ezzalzouli and Bartra have combined for 4 of their own.
Over 2.5Guirassy's 4 goals and Bartra's 2 for Betis show goals at both ends, with Dortmund's +1 and Betis's +3 goal difference pointing to an open game at Signal Iduna Park.
Serhou Guirassy to score anytimeGuirassy has scored 4 goals in 210 minutes this season, with 7 shots on target from 15 attempts underlining him as Dortmund's most reliable route to goal.
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Our approach: we weigh the table, recent form and individual player data to settle on one predicted scoreline, then build every pick that follows from the stats behind it.

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Season Form & Standings

Borussia Dortmund sit on 6 points from 3 games (2 wins, 1 loss, +1 goal difference), while Real Betis have made a perfect start with 9 points from 3 wins and a +3 goal difference.

Champions League

TeamPosGPWDLGFGAGDPts
Real Betis5330074+39
Borussia Dortmund13320154+16
Team News Predicted

Borussia Dortmund vs Real Betis Predicted Lineups

Predicted XI — updated for the latest team news.

Borussia Dortmund

3-1-2-2-2
G. Kobel
R. Bensebaini
N. Schlotterbeck
W. Anton
J. Veerman
D. Svensson
J. Ryerson
F. Nmecha
C. Chukwuemeka
Fabio Silva
S. Guirassy

Real Betis

4-2-3-1
Alvaro Valles
Fran Garcia
Natan
Marc Bartra
Hector Bellerin
Marc Roca
Pablo Fornals
A. Ezzalzouli
Isco
Antony
T. Parrott
    Squawka · Team News

    Potential Match-Winners

    • Serhou Guirassy (Borussia Dortmund): The striker has scored 4 goals already this season, backing that up with 15 shots and 7 on target in just 210 minutes on the pitch.
    • Joey Veerman (Borussia Dortmund): The midfielder has created 4 chances and claimed 1 assist in 240 minutes, the kind of creative platform Dortmund need to keep producing chances.
    • Marc Bartra (Real Betis): The defender has scored 2 goals already this season and remains Betis’s most dangerous aerial threat from set pieces.

    Recent Form

    Borussia Dortmund: W L W

    • 2026-10-20: Sabah 1-2 Borussia Dortmund (W, away)
    • 2026-10-14: Bodø / Glimt 1-0 Borussia Dortmund (L, away)
    • 2026-09-08: Borussia Dortmund 3-2 Villarreal (W, home)

    W-L-W across their last 3 matches, including a 3-2 home win over Villarreal and a 1-0 loss away to Bodø/Glimt.

    Real Betis: W W W

    • 2026-10-21: Real Betis 1-0 Feyenoord (W, home)
    • 2026-10-14: Real Betis 3-2 Porto (W, home)
    • 2026-09-08: Lille 2-3 Real Betis (W, away)

    W-W-W across their last 3 games, including a 1-0 home win over Feyenoord and a 3-2 away win at Lille.

    Borussia Dortmund vs Real Betis Prediction

    This looks tight before Dortmund’s extra quality shows late on. Guirassy’s movement should give Betis’s back line problems all night, while Bartra’s set-piece threat and Ezzalzouli’s directness mean the visitors won’t go quietly. Expect Borussia Dortmund to edge a 2-1 win at Signal Iduna Park.