Trade Markets
    Trade $10, Get $10 Bonus
    TRADE NOW!
    100% up to $50 with Code: ACQUIRE05
    PLAY NOW!
    Up to $100 in Bonus Cash
    Spend 5 get $50 in Novig Coins CODE:SQUAWKA
    Home » News » Leagues Cup » Philadelphia Union vs Santos Laguna: Predictions, Picks, Odds & Lineups

    Philadelphia Union vs Santos Laguna: Predictions, Picks, Odds & Lineups

    Philadelphia Union vs Santos Laguna predicted lineups Leagues Cup

    Predicted lineups: Philadelphia Union are set up in a 4-4-2 and Santos Laguna in a 4-2-3-1, with both probable XIs in full below.

    In the US, the match streams on Apple TV via MLS Season Pass.

    The market has the Union as a 67% favorite, Santos Laguna at just 15%, and a level-after-90 penalty shootout scenario at 17%. This is Philadelphia’s third and final Phase One game, with home advantage in an MLS market sharpening their edge. The no-draws format means any stalemate goes straight to penalties, with the winner banking two points and the loser claiming one. Kickoff at Subaru Park is set for 7:00 PM ET / 6:00 PM CT / 4:00 PM PT on Thursday, August 13.

    Philadelphia Union vs Santos Laguna: Best Bets & Predictions

    Home edge and the shootout safety net make the Union the play, but the goals market offers sharper value.

    Where are you following from? Odds & offers below update to match.
    Philadelphia Union to WinTop pickSubaru Park has been a fortress in Phase One, and Kalshi’s 67% reflects the Union’s home record and Santos Laguna’s travel disadvantage in knockout soccer.
    67%win prob.Opening soon @ bet365
    Both Teams to Score: YesSantos Laguna will need to chase points and can’t sit deep, while the Union’s front line has delivered at home throughout the group stage.
    57%chanceOpening soon @ bet365
    Over 2.5 GoalsThe penalty-shootout safety net removes late-game caution, and both sides have shown they’ll push numbers forward when two points are on the line.
    66%chanceOpening soon @ bet365

    Our approach: back the favorite on home turf, then lean into the goals given both sides need points and the shootout cushion encourages attacking intent.

    Trade these markets on KalshiNew users get $10 — trade $10 to unlock. Prices update live.
    Trade on Kalshi →
    Kalshi review

    Probabilities reflect live Kalshi market prices at time of loading. 21+. Prediction markets are CFTC-regulated event contracts, not sportsbook bets. Please play responsibly. Gambling Problem? Call 1-800-GAMBLER. New Kalshi users: USE CODE SQUAWKA.

    Back these with bet365Leagues Cup prices open closer to kick-off — check bet365 for the latest.
    Bet with bet365 →
    bet365 review

    Odds shown in American format for illustration; your local odds and offer are served on click. Eligibility, minimum age (18+/21+) and T&Cs vary by region. Please gamble responsibly.

    How Leagues Cup Phase One works

    Every club in the Leagues Cup plays three cross-league games, MLS against Liga MX. There are no draws. If the score is level after 90 minutes, the game goes straight to a penalty shootout, and the winner banks two points while the loser takes one. The top four MLS teams and the top four Liga MX teams then advance to the knockout rounds.

    Shop the matchPhiladelphia Union v Santos LagunaOfficial kits via Fanatics
    Squawka may earn a commission when you buy through these links, at no extra cost to you. Prices are set by the retailer and correct at time of publishing.
    Team News Predicted

    Philadelphia Union vs Santos Laguna Predicted Lineups

    Predicted XI — updated for the latest team news.

    Philadelphia Union

    4-4-2
    A. Blake
    K. Wagner
    N. Harriel
    Neil Pierre
    F. Westfield
    I. Vassilev
    J. Lukic
    D. Jean Jacques
    C. Sullivan
    M. Iloski
    B. Damiani

    Santos Laguna

    4-2-3-1
    C. Acevedo
    E. Echeverria
    F. Sanchez
    F. Pardo
    M. Cuevas
    S. Mariscal
    A. Lopez
    R. Sordo
    Fran Villalba
    E. Bullaude
    E. Aguirre
      Squawka · Team News

      Philadelphia Union vs Santos Laguna prediction

      The Union should have enough firepower to claim all two points, but Santos Laguna’s desperation for a result means this one opens up after the break. Prediction: Philadelphia Union to win, 2-1.

      21+ | Gambling Problem? Call 1-800-GAMBLER | Odds approximate at time of writing