After a 1-0 defeat in Turkey, Liverpool will look to turn things around against Galatasaray in the Champions League last-16 second leg this week.
Kick-off at Anfield is set for 4:00 PM ET on Wednesday night, so expect intensity in what could be another memorable European evening on Merseyside.
Liverpool produced a famous European comeback in the first leg of their 2019 semi-final against Barcelona, and they will need similar inspiration here.
Mario Lemina’s early goal in Istanbul has given the Turkish side a narrow but vital advantage, leaving Arne Slot’s men with work to do if they are to reach the quarterfinals.
Best Bets & Predictions
Based on recent scoring trends and player form, here are our top betting recommendations for this match. We’re looking at defensive solidity and set-piece threats as key factors at Anfield.
| Our Prediction | Odds & Bookmaker | Confidence | Why We’re Backing It |
|---|---|---|---|
| Both Teams To Score – No | +110 @ Bet365 | ⭐⭐⭐ | Liverpool have kept 4 clean sheets in 9 European outings. Galatasaray’s xG is modest for the number of games played. |
| Virgil van Dijk Over 1.5 Shots | +163 @ Bet365 | ⭐⭐⭐ | Virgil van Dijk is always a threat in the opposition penalty area from set-pieces. His shot totals in home matches in the Champions League this term are quite remarkable. His figures read: 4, 5, 2, 3. |
How Both Teams Go Into Liverpool vs Galatasaray
Liverpool welcome Galatasaray to Anfield needing to overturn a 1–0 deficit from the first leg of their Champions League round of 16 tie. Mario Lemina’s early goal in the seventh minute proved decisive in Istanbul, giving the Turkish side a narrow but important advantage heading into the return match.
Liverpool have produced famous European comebacks in the past, although they have only overturned a first-leg defeat twice in the Champions League knockout stages. Those successes came in memorable semi-final ties against Chelsea in 2007 and Barcelona in 2019. Arne Slot’s side head into the game in mixed form after a 1–1 Premier League draw with Tottenham, leaving them with three wins, one draw, and two defeats from their last six matches.
Despite that inconsistency, Anfield remains a difficult place for visiting teams in Europe. Liverpool have won 15 of their last 19 UEFA matches at home and also hold a strong record against Turkish opposition on Merseyside. Galatasaray arrive with confidence after winning five of their previous six games and are aiming to reach the Champions League quarterfinals for the first time since the 2012–13 season.
Head-to-Head: Recent Meetings
Galatasaray have had the edge in recent meetings, winning both games this season without conceding. The Reds have yet to find the net against the Turkish side in 2025/26.
| Date | Score | Competition |
|---|---|---|
| March 10, 2026 | Galatasaray 1-0 Liverpool | Champions League |
| September 30, 2025 | Galatasaray 1-0 Liverpool | Champions League |
Liverpool vs Galatasaray prediction
Liverpool’s superior stats across attack and defense, combined with home advantage and Galatasaray’s recent discipline issues, point to a strong chance of the Reds taking all three points. Yet, with Galatasaray having frustrated Liverpool twice already this season, the question remains — can the hosts finally break their duck against the Turkish side? Our top pick is for both teams not to score (Odds +110) and for Virgil van Dijk to have Over 1.5 shots (Odds +163) with Bet365.
Odds correct at the time of writing. Please gamble responsibly.
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