Club Leon vs Atletico San Luis: Predictions, Picks, Odds & Lineups

Club Leon host Atletico San Luis at Estadio Leon (Nou Camp) on Monday, September 14 (9:00 PM ET / 8:00 PM CT / 6:00 PM PT).

There’s no fresh team news to report on the availability front for either side ahead of this one, so Club Leon and Atletico San Luis should both be able to pick from full-strength squads at Estadio Leon. For the hosts, that means Daniel Felipe Arcila Rojas and Jordi Cortizo de la Piedra keep their places at the top of the team sheet, the pair responsible for 5 goals between them already this campaign. Atletico San Luis will lean on Rafael Nicolas Llorente Sanz and David Rodriguez Uribe, who have combined for 5 goals and 32 shots between them this term.

US viewers can watch Club Leon vs Atletico San Luis on ViX, TUDN or Fox.

Club Leon vs Atletico San Luis: Best Bets & Predictions

Leon look to build on a solid home record as Atletico San Luis visit Estadio Leon.

Where are you following from? Odds & offers below update to match.

🇺🇸 United StatesTrade on Kalshi 🌎 Outside the USOdds via bet365

Club LeonTop pickLeon have collected 10 points from 6 games this Apertura, with home wins over Monterrey (2-0) and Pachuca (1-0) built on the goal threat of Daniel Felipe Arcila Rojas, who already has 3 goals from 390 minutes.

44%win prob.opening soon @ bet365

2-1 Club LeonLeon have posted 2-0 and 1-0 scorelines in recent home wins, while San Luis have shown enough going forward – a 3-1 away win at Monterrey included – to threaten a goal of their own.

⭐⭐⭐⭐⭐chanceopening soon @ bet365

YesDavid Rodriguez Uribe has 2 goals and Rafael Nicolas Llorente Sanz has 3 for San Luis this term, giving the visitors enough firepower to trouble a Leon defense that shipped a goal at Atlante and lost 1-0 at Tijuana in recent outings.

59%chanceopening soon @ bet365

Over 2.5Arcila's 3 goals and Llorente's 3 goals headline both attacks, and recent scorelines – Leon's 2-0 and 2-1 wins among them – suggest goals at both ends here too.

57%chanceopening soon @ bet365

Daniel Felipe Arcila Rojas to Score Anytime3 goals in 390 minutes, with 15 shots and 7 on target, underline how central Arcila is to Leon's attack.

⭐⭐⭐⭐⭐chanceopening soon @ bet365

Our approach: we lean on Signal's model output for the four core markets and back it up with the underlying goals, shots and chance-created data for both squads to explain the reasoning in plain terms.

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Season Form & Standings

Club Leon head into this one with 10 points from six games so far this Apertura, a +2 goal difference reflecting a solid home record at Estadio Leon. Atletico San Luis’s league placing isn’t reflected in the numbers here, but their recent form – a 3-1 win at Monterrey and a 3-0 home loss to Chivas among them – tells its own story ahead of this trip.

Liga MX

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Potential Match-Winners

• Daniel Felipe Arcila Rojas (Club Leon): 3 goals and 10 chances created in 390 minutes make him Leon’s most dangerous outlet in the final third.
• Jordi Cortizo de la Piedra (Club Leon): 2 goals and a team-high 11 chances created show his influence both scoring and creating for Leon.
• Rafael Nicolas Llorente Sanz (Atletico San Luis): 3 goals from 19 shots (8 on target) in 515 minutes make him San Luis’s likeliest source of a response.

Recent Form

Club Leon: L W W W D

• 2026-08-28: Atlante FC 1-1 Club Leon (D, away)
• 2026-08-21: Club Leon 2-0 Monterrey (W, home)
• 2026-08-17: Necaxa 1-2 Club Leon (W, away)
• 2026-08-01: Club Leon 1-0 Pachuca (W, home)
• 2026-07-24: Club Tijuana 1-0 Club Leon (L, away)

Leon go into this on the back of a 1-1 draw at Atlante, following wins over Monterrey (2-0), Necaxa (2-1 away) and Pachuca (1-0), with a 1-0 loss at Tijuana their only other result in this stretch.

Atletico San Luis: D L D W L

• 2026-09-06: Atletico San Luis 0-3 Chivas (L, home)
• 2026-08-30: Monterrey 1-3 Atletico San Luis (W, away)
• 2026-08-23: Atletico San Luis 1-1 Pachuca (D, home)
• 2026-08-16: Club America 3-0 Atletico San Luis (L, away)
• 2026-07-31: Atletico San Luis 0-0 Club Tijuana (D, home)

Atletico San Luis arrive off the back of a 3-0 home defeat to Chivas, though that followed a 3-1 win at Monterrey, a 1-1 draw with Pachuca and a scoreless draw with Tijuana, sandwiched around a 3-0 loss at Club America.

Club Leon vs Atletico San Luis Prediction

Leon have accumulated 10 points from 6 games this Apertura, a +2 goal difference built on home wins over Monterrey and Pachuca, and home advantage at Estadio Leon should be enough to see off a San Luis side who have scored goals of their own but leaked plenty at the other end, including 3 without reply in their last outing against Chivas. Expect Daniel Felipe Arcila Rojas and Jordi Cortizo de la Piedra to find the net for the hosts, with Rafael Nicolas Llorente Sanz pulling a goal back for the visitors, in a 2-1 win for Club Leon.