Atlante FC vs Santos Laguna: Predictions, Picks, Odds & Lineups

Atlante FC host Santos Laguna at Estadio Azteca on Friday, November 6 (10:00 PM ET / 9:00 PM CT / 7:00 PM PT).

Atlante FC have no injury or suspension concerns flagged heading into this one, and the headline act remains unchanged: midfielder Luis Angel Calzadilla, Atlante’s top scorer with three goals in 1,084 minutes, and striker Jhojan Julio Palacios, who has supplied four assists and a team-high 22 chances created this season. Santos Laguna are similarly unaffected by injury or suspension news, with midfielder Ezequiel Bullaude (three goals, four assists, 35 shots) and striker Tahiel Jimenez — five goals already from just 274 minutes — the two likely to carry the visitors’ threat forward.

This looks set up as a low-scoring, cagey affair rather than an end-to-end shootout. Atlante have won twice in their last five matches and been shut out on two other occasions, a pattern that points to a tight scoreline at the newly adopted Estadio Azteca. Santos Laguna sit on 19 points from 14 games (6 wins, 1 draw, 7 losses) and travel to the capital on the back of a 4-1 defeat at Club Tijuana, a damaging result that raises questions about their away-day form against a side determined to make home advantage count.

US viewers can watch Atlante FC vs Santos Laguna on ViX, TUDN or Fox.

Season Form & Standings

Santos Laguna arrive on 19 points from 14 games this season (6 wins, 1 draw, 7 losses), a mid-pack return built on a stop-start run. Atlante’s league account still reads zero across the board in our table, with the newly promoted side only just settling into life at Estadio Azteca after the move up.

Liga MX

Shop the matchAtlante v Santos LagunaOfficial kits via Fanatics

CharlyMen's Charly Green Santos Laguna 2026/27 Home Authentic Jersey$95.00ShopCharlyMen's Charly White Santos Laguna 2026/27 Away Authentic Jersey$95.00Shop

Squawka may earn a commission when you buy through these links, at no extra cost to you. Prices are set by the retailer and correct at time of publishing.

Potential Match-Winners

• Luis Angel Calzadilla Santillan (Atlante FC): The midfielder leads Atlante’s scoring with 3 goals and has created 13 chances across 1,084 minutes this season.
• Jhojan Esmaider Julio Palacios (Atlante FC): The striker has set up 4 assists and created a team-high 22 chances for Atlante, adding 2 goals of his own from 29 shots.
• Ezequiel Eduardo Bullaude (Santos Laguna): The midfielder has 3 goals and 4 assists for Santos this season, adding 20 chances created from 1,173 minutes on the field.

Recent Form

Atlante FC: W L L W L

• 2026-10-23: Atlante FC 0-1 Atletico San Luis (L, home)
• 2026-10-20: FC Juarez 0-1 Atlante FC (W, away)
• 2026-10-16: Atlante FC 1-2 Pumas UNAM (L, home)
• 2026-10-10: Queretaro FC 2-0 Atlante FC (L, away)
• 2026-09-25: Atlante FC 4-2 Monterrey (W, home)

Atlante’s last five league games have brought two wins and three losses. The wins came 4-2 at home to Monterrey and 1-0 away at FC Juarez, while the defeats included a 1-2 loss to Pumas UNAM, a 2-0 defeat at Queretaro, and a 1-0 loss to Atletico San Luis most recently.

Santos Laguna: W W W W L

• 2026-10-25: Club Tijuana 4-1 Santos Laguna (L, away)
• 2026-10-21: Santos Laguna 2-0 Pumas UNAM (W, home)
• 2026-10-17: Santos Laguna 5-0 Queretaro FC (W, home)
• 2026-10-11: Atletico San Luis 1-2 Santos Laguna (W, away)
• 2026-09-26: Santos Laguna 1-0 Pachuca (W, home)

Santos Laguna have won four of their last five league matches, losing only the most recent one. Victories came 2-0 at home to Pumas UNAM, 5-0 at home to Queretaro, 2-1 away at Atletico San Luis, and 1-0 at home to Pachuca, before a 4-1 defeat at Club Tijuana ended the run.

Atlante FC vs Santos Laguna Prediction

Signal has this finishing 1-0 to Atlante FC, a tight home win built on defensive solidity rather than fireworks. Santos Laguna’s 19 points from 14 games (6 wins, 1 draw, 7 losses) make them no pushovers, but a 4-1 defeat at Club Tijuana last time out suggests the away form isn’t currently strong enough to get something from Estadio Azteca. Expect Atlante to find the game’s only goal and see it out: Atlante FC 1-0 Santos Laguna.