PSV vs Shakhtar Donetsk: Predictions, Picks, Odds & Stats

PSV host Shakhtar Donetsk on Thursday, September 10 (12:45 PM ET / 11:45 AM CT / 9:45 AM PT).

The injured Adamo Nagalo, Mikkel Bro, Kilian Sildillia, Dennis Man and Alassane Plea are all out for PSV, and the cruciate-ligament-sidelined Jerdy Schouten adds another absence to a lengthy list. That leaves PSV’s attack shaped around Ricardo Pepi, Guus Til and Ivan Perišić, all regulars last season, with Mauro Júnior’s creativity also part of the picture as PSV host Shakhtar Donetsk.

Shakhtar arrive as clear outsiders on paper, and PSV’s injury list has done little to shift the wider sentiment toward an upset. The link play from Til, the directness of Perišić and the finishing of Pepi give PSV more attacking outlets than Shakhtar can call upon, and that gap in individual quality should tell over the course of the game.

US viewers can watch PSV vs Shakhtar Donetsk on Paramount+.

PSV vs Shakhtar Donetsk: Best Bets & Predictions

PSV heavily fancied at home despite a lengthy PSV injury list

Where are you following from? Odds & offers below update to match.

🇺🇸 United StatesTrade on Kalshi 🌎 Outside the USOdds via bet365

PSV WinTop pickPSV's attacking options, led by last season's returns from Pepi, Til and Perišić, make them the clear favorites at home.

69%win prob.-225 @ bet365

BTTS – YesPSV's attack looks sharp enough to score regardless, and Shakhtar should find a way to get on the board too.

62%chance-163 @ bet365

Over 2.5 GoalsWith PSV's forward line built around proven scorers from last season, this fixture is shaped to produce plenty of goals.

67%chance-200 @ bet365

Correct Score: PSV 2-1 Shakhtar DonetskA two-goal home win with an away consolation ties together the win, the over two.5 lean and the BTTS pick.

12%chance750 @ bet365

Anytime Goalscorer: Ricardo PepiPepi scored 3 goals last season and landed 6 of his 8 shots on target, showing a clinical eye in front of goal.

⭐⭐⭐⭐⭐chanceopening soon @ bet365

Our approach: we lean on last season's underlying numbers for PSV's key attackers, weigh the confirmed absentee list, and build the picks so the result, goals markets and scoreline all point the same direction.

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Season Form & Standings

Neither side has kicked a ball in this season’s competition yet: PSV and Shakhtar Donetsk both sit on 0 points from 0 games played, making Thursday’s meeting the opening test of the league phase for both clubs.

Recent domestic form. Here’s PSV’s domestic form ahead of the European opener:

Potential Match-Winners

• Ricardo Pepi (PSV): Ricardo Pepi scored 3 goals last season from just 149 minutes on the pitch, landing 6 of his 8 shots on target.
• Guus Til (PSV): Guus Til supplied 3 assists and created 9 chances last season to go with 2 goals of his own, the clearest creative outlet in this PSV side.
• Ivan Perišić (PSV): Ivan Perišić fired 11 shots and created 5 chances last season, adding 1 goal and 1 assist along the way.

PSV vs Shakhtar Donetsk Prediction

PSV sit on 0 points from 0 games so far, level with Shakhtar Donetsk, but the class gap suggested by the markets points to a home win, and we’re backing that to arrive with goals at both ends, closing out 2-1 to the home side.