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Home » News » Champions League » Manchester United vs Roma: Predictions, Picks, Odds & Lineups

Manchester United vs Roma: Predictions, Picks, Odds & Lineups

Manchester United vs Roma predicted formations

Manchester United host Roma at Old Trafford on Tuesday, November 3 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).

Manchester United and Roma head into this one with no fresh injury concerns flagged for either squad, so both sides should be close to full strength. Bruno Fernandes, who has a goal and 7 chances created from 237 minutes this campaign, looks the likely creative focal point for United, with Matheus Cunha and Joshua Zirkzee both in contention after scoring in their limited minutes so far. Roma’s team news centers on Donyell Malen, who has 3 goals and 2 assists from 13 shots in 236 minutes — by far their most involved attacker through 3 games this season.

US viewers can watch Manchester United vs Roma on Paramount+.

Squawka Signal
Match outcome · who wins
Manchester UnitedManchester United47%mkt 41%Our pick
DrawDraw22%mkt 24%
RomaRoma32%mkt 36%

Manchester United vs Roma: Best Bets & Predictions

The market prices Manchester United at 41%. Signal says 47%.

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The tips · best bets
MarketMkt %Signal %Read
Correct ScoreManchester United 2-1 RomaRoma have conceded in 2 of their last 3 games, and with United finding the net through multiple players at home, a 2-1 scoreline fits the model's read of goals at both ends.
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9%
Model read
›
Both Teams to ScoreBoth teams to scoreRoma have scored in all 3 league games so far, and United's front line has goals spread across Fernandes, Cunha, Zirkzee and Šeško, so goals at both ends look the likely outcome.
64%
69%
Value
›
Over / Under 2.5Over 2.5With 5 different United players already among the goals and Roma shipping 4 in their last defeat, this fixture looks set to clear the Over 2.5 line comfortably.
64%
68%
Value
›
Anytime ScorerBruno Fernandes to score anytimeFernandes leads United's attacking players for shots in this sample, with 7 shots and 3 on target, and he's already off the mark with a goal in 237 minutes.
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Model read
Signal edge callsRecord building · settles at full-time

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Season Form & Standings

Manchester United have taken 3 points from 3 games this season, with a goal difference of -1, while Roma have 4 points from 3 games and a goal difference of +3.

Champions League

TeamPosGPWDLGFGAGDPts
Roma15311185+34
Manchester United21310256-13
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Team News Predicted

Manchester United vs Roma Predicted Lineups

Predicted XI — updated for the latest team news.

Manchester United

4-2-3-1
S. Lammens
N. Mazraoui
H. Maguire
M. de Ligt
Diogo Dalot
Andrey Santos
M. Mount
Matheus Cunha
Y. Tielemans
B. Mbeumo
Bruno Fernandes

Roma

3-4-2-1
P. Gollini
Mario Hermoso
L. Balerdi
D. Ghilardi
Wesley
N. Pisilli
M. de Roon
N. Molina
L. Pellegrini
Rodrigo Mora
D. Malen
    Squawka · Team News

    Potential Match-Winners

    • Bruno Fernandes (Manchester United): The striker has a goal, 7 shots (3 on target) and 7 chances created from 237 minutes, making him United’s most involved attacking outlet this season.
    • Matheus Cunha (Manchester United): The attacking midfielder has a goal from 6 shots, landing 4 on target in just 145 minutes — an efficient return in limited time.
    • Donyell Malen (Roma): Roma’s standout performer has 3 goals and 2 assists from 13 shots (6 on target) in 236 minutes, making him the most productive player in this preview.

    Recent Form

    Manchester United: W L L

    • 2026-10-21: Como 4-1 Manchester United (L, away)
    • 2026-10-13: Atletico Madrid 2-0 Manchester United (L, away)
    • 2026-09-10: Manchester United 4-0 Sabah (W, home)

    Manchester United’s form reads W L L — a 4-0 win over Sabah followed by back-to-back defeats, 2-0 at Atletico Madrid and 4-1 at Como.

    Roma: D L W

    • 2026-10-20: Roma 4-0 Slovan Bratislava (W, home)
    • 2026-10-14: Roma 3-4 Real Madrid (L, home)
    • 2026-09-10: Fenerbahce 1-1 Roma (D, away)

    Roma’s form reads D L W — a 1-1 draw at Fenerbahce, a 3-4 loss to Real Madrid, then a 4-0 win over Slovan Bratislava.

    Manchester United vs Roma Prediction

    Our Signal model has this finishing 2-1 to Manchester United. Home advantage and United’s knack for scoring across multiple players — Fernandes, Cunha, Zirkzee and Šeško have all found the net already this season — should be enough to see off a Roma side that have more points (4 to 3) but have also shown they can be breached, conceding 4 goals in a 3-4 home loss to Real Madrid. Expect goals at both ends, with Malen a threat throughout, before United’s greater firepower at Old Trafford tips it late.