RB Leipzig host PSV at Red Bull Arena on Tuesday, October 13 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).
No fresh fitness concerns have emerged on either side, so RB Leipzig should still call on Christopher Nkunku, Antonio Nusa, and David Raum as their attacking fulcrum, while Andrija Maksimović’s recent goal adds another option off the bench. PSV are expected to keep faith with the spine that drew at home to Shakhtar Donetsk, with Ruben van Bommel, Ivan Perišić, and Ricardo Pepi leading the forward line and Sergiño Dest pushing forward from the back.
RB Leipzig head into this one off the back of a chastening 4-1 defeat at Como that leaves them on 0 points and a goal difference of -three, while PSV have just 1 point after an opening draw with Shakhtar Donetsk. Both defenses have shown cracks early, and with Leipzig’s attacking group already finding the net and PSV posing a threat through Dest, Obispo, and van Bommel, this looks set to be an open, end-to-end contest in which the home side’s firepower edges it 2-1.
US viewers can watch RB Leipzig vs PSV on Paramount+.
RB Leipzig vs PSV: Best Bets & Predictions
Signal has RB Leipzig at 42% — no edge over the market on the result. The market’s soft on PSV (+7) — our value angle.
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Season Form & Standings
RB Leipzig have 0 points from 1 match and a goal difference of -3 after an opening defeat, while PSV have 1 point and a goal difference of 0 after their opening draw.
Champions League
| Team | Pos | GP | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| PSV | 20 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 |
| RB Leipzig | 32 | 1 | 0 | 0 | 1 | 1 | 4 | -3 | 0 |
RB Leipzig vs PSV Predicted Lineups
Predicted XI — updated for the latest team news.
RB Leipzig
4-4-2PSV
4-3-3Potential Match-Winners
- Andrija Maksimović (RB Leipzig): Maksimović is RB Leipzig’s only scorer so far, netting in 70 minutes and landing 2 shots on target from 2 attempts against Como.
- Christopher Nkunku (RB Leipzig): Nkunku created 3 chances and added an assist in 60 minutes against Como, showing he remains Leipzig’s chief creative outlet.
- Sergiño Dest (PSV): Dest’s goal against Shakhtar Donetsk came from the back line, and the defender remains a threat from set pieces rather than an out-and-out attacking outlet.
Recent Form
RB Leipzig: L
- 2026-09-10: Como 4-1 RB Leipzig (L, away)
RB Leipzig’s only Champions League outing ended in a 4-1 loss away to Como.
PSV: D
- 2026-09-10: PSV 1-1 Shakhtar Donetsk (D, home)
PSV’s sole game so far was a 1-1 draw at home to Shakhtar Donetsk.
RB Leipzig vs PSV Prediction
RB Leipzig’s attacking options — Maksimović, Nkunku, and Nusa chief among them — should have enough end product to get the better of a shaky PSV back line at home, even with the hosts still winless after an opening 4-1 loss to Como. PSV, who drew 1-1 with Shakhtar Donetsk to open with 1 point, look like the value side in this match-up and could easily take something from Leipzig, but our Signal model has this finishing 2-1 to RB Leipzig with goals at both ends.