Home » News » Champions League » Manchester United vs Roma: Predictions, Picks, Odds & Lineups

Manchester United vs Roma: Predictions, Picks, Odds & Lineups

Manchester United vs Roma predicted formations

Manchester United host Roma at Old Trafford on Tuesday, November 3 (3:00 PM ET / 2:00 PM CT / 12:00 PM PT).

Manchester United have no fresh fitness concerns to report, and Roma are in the same boat, so both managers should have a full group to pick from. Bruno Fernandes remains the man United will lean on creatively, with a goal and 7 chances created from his 237 minutes so far, while Matheus Cunha and Joshua Zirkzee offer the main attacking threats and Benjamin Šeško provides a route off the bench. Roma will again build around Donyell Malen, who already has 3 goals, 13 shots and 2 assists from 236 minutes, with Niccolò Pisilli and Nahuel Molina supporting from midfield.

Manchester United vs Roma: Best Bets & Predictions

Manchester United host Roma in a Champions League fixture that looks set to produce goals at both ends.

Manchester UnitedTop pickManchester United have 3 points from 3 games but Roma have shown they can be opened up, shipping 4 goals to Real Madrid and conceding 1 to Fenerbahce as well.
Manchester United 2-1 RomaWith Bruno Fernandes generating 7 chances created in limited minutes and Donyell Malen already on 3 goals for Roma, a tight 1-goal margin with scoring at both ends fits the data.
YesManchester United have scored 4 against Sabah and conceded 4 to Como this season, while Roma have scored 4 against Slovan Bratislava and conceded 4 to Real Madrid, so goals at both ends have been the pattern for each side.
Over 2.5Roma's last 2 matches have produced 4-0 and 3-4 scorelines, and Manchester United's have gone 4-1 and 4-0, pointing toward another game that clears 2.5 goals.
Bruno Fernandes to Score AnytimeBruno Fernandes has a goal, 7 shots and 7 chances created from just 237 minutes, making him Manchester United's most involved attacking outlet.
⭐⭐⭐⭐⭐chanceopening soon @ bet365

Our approach: ground every pick in verified standings, form and player data, then let the model's scoreline read set the Result, Correct Score, Both Teams to Score and Over 2.5 picks.

Back these with bet365Odds shown in American format; your local odds may vary.
Bet with bet365 → bet365 review

Odds correct at time of writing and shown in American format for illustration; your local odds may vary. 19+ (18+ in AB/MB/QC). Please play responsibly. ConnexOntario: 1-866-531-2600 (ON).

Season Form & Standings

Manchester United have 3 points from 3 games, with 1 win, 2 losses and a goal difference of -1, while Roma have 4 points from 3 games, with 1 win, 1 draw, 1 loss and a goal difference of +3.

Champions League

TeamPosGPWDLGFGAGDPts
Roma15311185+34
Manchester United21310256-13
Team News Predicted

Manchester United vs Roma Predicted Lineups

Predicted XI — updated for the latest team news.

Manchester United

4-2-3-1
S. Lammens
N. Mazraoui
H. Maguire
M. de Ligt
Diogo Dalot
Andrey Santos
M. Mount
Matheus Cunha
Y. Tielemans
B. Mbeumo
Bruno Fernandes

Roma

3-4-2-1
P. Gollini
Mario Hermoso
L. Balerdi
D. Ghilardi
Wesley
N. Pisilli
M. de Roon
N. Molina
L. Pellegrini
Rodrigo Mora
D. Malen
    Squawka · Team News

    Potential Match-Winners

    • Bruno Fernandes (Manchester United): Has a goal from his 7 shots so far, and leads the way for United with 7 chances created in only 237 minutes.
    • Matheus Cunha (Manchester United): Has scored once from 6 shots, 4 of which were on target, inside just 145 minutes of action.
    • Donyell Malen (Roma): Roma’s most direct route to goal, with 3 goals, 13 shots and 2 assists across 236 minutes.

    Recent Form

    Manchester United: W L L

    • 2026-10-21: Como 4-1 Manchester United (L, away)
    • 2026-10-13: Atletico Madrid 2-0 Manchester United (L, away)
    • 2026-09-10: Manchester United 4-0 Sabah (W, home)

    Manchester United have lost 2 straight — 4-1 away to Como and 2-0 away to Atletico Madrid — after an opening 4-0 win over Sabah.

    Roma: D L W

    • 2026-10-20: Roma 4-0 Slovan Bratislava (W, home)
    • 2026-10-14: Roma 3-4 Real Madrid (L, home)
    • 2026-09-10: Fenerbahce 1-1 Roma (D, away)

    Roma won their most recent outing 4-0 against Slovan Bratislava, following a 3-4 loss to Real Madrid and an opening 1-1 draw at Fenerbahce.

    Manchester United vs Roma Prediction

    This looks set to finish 2-1 to Manchester United, with goals likely at both ends rather than a cagey afternoon. Bruno Fernandes, already on a goal and 7 chances created this season, looks the most likely source for the hosts, while Donyell Malen’s 3 goals from 13 shots make him Roma’s clearest threat. Expect Manchester United, on 3 points from 3 games, to edge a Roma side sitting on 4 points from the same number of matches.