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    Home » News » Leagues Cup » Chicago Fire vs Santos Laguna: Predictions, Picks, Odds & Lineups

    Chicago Fire vs Santos Laguna: Predictions, Picks, Odds & Lineups

    Chicago Fire vs Santos Laguna predicted lineups Leagues Cup

    Predicted lineups: Chicago Fire are set up in a 4-4-2 and Santos Laguna in a 4-2-3-1, with both probable XIs in full below.

    In the US, the match streams on Apple TV via MLS Season Pass.

    Kalshi prices the Fire at 63% to win inside ninety minutes, reflecting the home advantage and MLS venue edge that defines Phase One. Santos Laguna sit at just 18%, with the remaining 20% pointing toward a level scoreline and a penalty shootout. This is Chicago’s second of three group games, and the format leaves no room for a share of the spoils. Kickoff at SeatGeek Stadium is set for 8:00 PM ET / 7:00 PM CT / 5:00 PM PT on Sunday, August 9.

    Club profiles: Chicago Fire fixtures, form & stats · Santos Laguna fixtures, form & stats

    Chicago Fire vs Santos Laguna: Best Bets & Predictions

    The clearest value sits in the goals markets, where both the Over 2.5 and BTTS Yes trade above 60%.

    Where are you following from? Odds & offers below update to match.
    Chicago Fire to WinTop pickHome advantage in Phase One is meaningful, and a 63% favorite reflects SeatGeek Stadium and the MLS hosting edge without overstating the gap.
    63%win prob.Opening soon @ bet365
    Both Teams to Score: YesBoth sides need to attack in a format that punishes caution, and a 61% BTTS read suggests neither can afford to sit deep.
    61%chanceOpening soon @ bet365
    Over 2.5 GoalsThe strongest probability on the board at 66%, driven by the no-draws urgency and both teams knowing a shootout rewards goals scored.
    66%chanceOpening soon @ bet365

    Our approach: lean to the goals rather than splitting hairs on a coin-flip result.

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    Probabilities reflect live Kalshi market prices at time of loading. 21+. Prediction markets are CFTC-regulated event contracts, not sportsbook bets. Please play responsibly. Gambling Problem? Call 1-800-GAMBLER. New Kalshi users: USE CODE SQUAWKA.

    Back these with bet365Leagues Cup prices open closer to kick-off — check bet365 for the latest.
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    Odds shown in American format for illustration; your local odds and offer are served on click. Eligibility, minimum age (18+/21+) and T&Cs vary by region. Please gamble responsibly.

    How Leagues Cup Phase One works

    Every club in the Leagues Cup plays three cross-league games, MLS against Liga MX. There are no draws. If the score is level after 90 minutes, the game goes straight to a penalty shootout, and the winner banks two points while the loser takes one. The top four MLS teams and the top four Liga MX teams then advance to the knockout rounds.

    Team News Predicted

    Chicago Fire vs Santos Laguna Predicted Lineups

    Predicted XI — updated for the latest team news.

    Chicago Fire

    4-4-2
    C. Brady
    A. Gutman
    J. Elliott
    J. Waterman
    Leonardo Barroso
    J. Bamba
    A. Saletros
    T. D'Avilla
    P. Zinckernagel
    R. Lod
    R. Lewandowski

    Santos Laguna

    4-2-3-1
    C. Acevedo
    E. Echeverria
    F. Sanchez
    F. Pardo
    M. Cuevas
    S. Mariscal
    A. Lopez
    R. Sordo
    Fran Villalba
    E. Bullaude
    E. Aguirre
      Squawka · Team News

      Chicago Fire vs Santos Laguna prediction

      Chicago Fire should have enough at home to edge Santos Laguna, but expect goals at both ends as the Phase One format compresses risk and reward into ninety minutes. Prediction: Chicago Fire to win, 3-2.

      21+ | Gambling Problem? Call 1-800-GAMBLER | Odds approximate at time of writing