{"id":82560,"date":"2026-10-28T07:02:54","date_gmt":"2026-10-28T11:02:54","guid":{"rendered":"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/colts-vs-jaguars-prediction-picks-odds-week-8\/"},"modified":"2026-10-28T07:02:53","modified_gmt":"2026-10-28T11:02:53","slug":"colts-vs-jaguars-prediction-picks-odds-week-8","status":"publish","type":"nfl-news","link":"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/colts-vs-jaguars-prediction-picks-odds-week-8\/","title":{"rendered":"Colts vs Jaguars Prediction, Picks &#038; Odds"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Jacksonville concede 3.23 yards a carry, the best run defense in the NFL, and have given up 11 touchdowns in six games. Our <strong>Colts vs Jaguars prediction<\/strong> sends a 69.4 passing game at them.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/www.squawka.com\/us\/nfl\/teams\/jacksonville-jaguars\/\">Jacksonville Jaguars<\/a> are 4-2 at +50 and back at EverBank after two home games in London. The <a href=\"https:\/\/www.squawka.com\/us\/nfl\/teams\/indianapolis-colts\/\">Indianapolis Colts<\/a> are 2-5 and Daniel Jones has four touchdown passes to seven interceptions.<\/p>\n\n\n\n<!-- SQ_NFL_SIG_START -->\n\n<style>\n.sq-nsig{position:relative;overflow:hidden;border-radius:18px;margin:28px 0;isolation:isolate;background:radial-gradient(70% 90% at 18% 0%,rgba(47,230,201,.14) 0%,rgba(47,230,201,0) 60%),linear-gradient(135deg,#0a2540 0%,#06182b 60%,#040f1d 100%);box-shadow:0 18px 44px rgba(4,15,29,.5);font-family:'Bricolage 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.sq-nsig__geo-b,.sq-nsig__geo-r--b:checked~.sq-nsig__cta-row .sq-nsig__geo-b{display:contents}\n<\/style>\n<div class=\"sq-nsig\"><div class=\"sq-nsig__inner\"><span class=\"sq-nsig__tag\"><span class=\"dot\"><\/span>Squawka Signal &middot; Model vs market<\/span><h3 class=\"sq-nsig__title\">Indianapolis Colts @ Jacksonville Jaguars<\/h3><p class=\"sq-nsig__meta\">Week 8 &middot; Sun Nov 1, 1:00 PM ET. Our Signal model makes the <b>Jacksonville Jaguars<\/b> favorites by about <b>9<\/b> points, a 80% win probability.<\/p><div class=\"sq-nsig__cards\"><div class=\"sq-nsig__card\"><div class=\"sq-nsig__sum\"><img decoding=\"async\" class=\"sq-nsig__crest\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/IND.png\" alt=\"IND\" loading=\"lazy\" width=\"30\" height=\"30\"><span class=\"sq-nsig__name\">Indianapolis Colts<\/span><span class=\"sq-nsig__cmp\"><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Squawka<\/span><span class=\"sq-nsig__cmp-sig\">20%<\/span><\/span><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Market<\/span><span class=\"sq-nsig__cmp-mkt\">20%<\/span><\/span><span class=\"sq-nsig__verd sq-nsig__verd--fair\">&#9644; Fair<\/span><\/span><\/div><\/div><div class=\"sq-nsig__card\"><div class=\"sq-nsig__sum\"><img decoding=\"async\" class=\"sq-nsig__crest\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/JAC.png\" alt=\"JAC\" loading=\"lazy\" width=\"30\" height=\"30\"><span class=\"sq-nsig__name\">Jacksonville Jaguars<\/span><span class=\"sq-nsig__cmp\"><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Squawka<\/span><span class=\"sq-nsig__cmp-sig\">80%<\/span><\/span><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Market<\/span><span class=\"sq-nsig__cmp-mkt\">80%<\/span><\/span><span class=\"sq-nsig__verd sq-nsig__verd--fair\">&#9644; Fair<\/span><\/span><\/div><\/div><\/div><div class=\"sq-nsig__mc\"><span class=\"sq-nsig__mc-k\">Projected line<\/span><span class=\"sq-nsig__mc-v\">Jacksonville Jaguars -9<\/span><\/div><div class=\"sq-nsig__cta-row\" style=\"margin-top:14px\"><a class=\"sq-nsig__cta2\" href=\"https:\/\/www.squawka.com\/us\/go\/kalshi?q=us-all-all-wof-s-spo\" rel=\"sponsored nofollow\" target=\"_blank\">Kalshi<\/a><a class=\"sq-nsig__cta2\" href=\"https:\/\/www.squawka.com\/us\/go\/polymarket?q=us-sg1-all-wof-s-spo\" rel=\"sponsored nofollow\" target=\"_blank\">Polymarket<\/a><a class=\"sq-nsig__cta2\" href=\"https:\/\/www.squawka.com\/us\/go\/prophet-x?q=us-sg1-all-wof-s-spo\" rel=\"sponsored nofollow\" target=\"_blank\">ProphetX<\/a><\/div><p class=\"sq-nsig__foot\">Squawka Signal is our model&#8217;s read against devigged market prices, updated after every result &mdash; not betting advice. <a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/nfl-signal-methodology\/\">How the NFL Signal works<\/a>. 21+. Play responsibly. 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class=\"sqp\" id=\"sqp-indjac\">\n<div class=\"sqp__wrap\">\n<span class=\"sqp__kick\">Week 8 &middot; Editorial pick<\/span>\n<h2 class=\"sqp__ttl\">Colts vs Jaguars: our editor&#8217;s props<\/h2>\n<p class=\"sqp__sub\" data-props=\"2\">Two calls from our editor, to read next to Signal&#8217;s live numbers.<\/p>\n<div class=\"sqp__crests\">\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/IND.png\" alt=\"Colts\" loading=\"lazy\" width=\"28\" height=\"28\">\n<span class=\"sqp__at\">AT<\/span>\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/JAC.png\" alt=\"Jaguars\" loading=\"lazy\" width=\"28\" height=\"28\">\n<\/div>\n<h3 class=\"sqp__h3\">Our props<\/h3>\n<div class=\"sqp__list\">\n<div class=\"sqp__row\" data-market=\"Total\" data-selection=\"Under 42.5 points\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Total<\/span><span class=\"sqp__pk\">Under 42.5 points<\/span><span class=\"sqp__why\">Jacksonville concede 3.23 a carry and 40.0% in the red zone, the best marks in the NFL. Indianapolis rate 69.4 through the air.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 3 of 5\">&#9733;&#9733;&#9733;<span class=\"o\">&#9734;&#9734;<\/span><\/span><span class=\"sqp__lab\">3\/5 confidence<\/span><\/div>\n<\/div>\n<div class=\"sqp__row\" data-market=\"Player prop\" data-selection=\"Trevor Lawrence 2+ passing touchdowns\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Player prop<\/span><span class=\"sqp__pk\">Trevor Lawrence 2+ passing touchdowns<\/span><span class=\"sqp__why\">Lawrence has 14 touchdown passes to four interceptions at 106.2. Indianapolis allow a 97.4 opponent rating.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 3 of 5\">&#9733;&#9733;&#9733;<span class=\"o\">&#9734;&#9734;<\/span><\/span><span class=\"sqp__lab\">3\/5 confidence<\/span><\/div>\n<\/div>\n<\/div>\n<p class=\"sqp__foot\">An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.<\/p>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Colts vs Jaguars: 2026 form so far<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A +50 team against a -26 team, and the gap is mostly one side of the ball. The table sets each attack against what the opposite defense has actually allowed.<\/p>\n\n\n\n<h3>Colts attack against the Jaguars defense<\/h3>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Per game<\/th><th>Colts offense<\/th><th>Jaguars allow<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Passing yards<\/td><td>180.4<\/td><td>273.8<\/td><\/tr>\n<tr><td>Rushing yards<\/td><td>117.6<\/td><td>72.2<\/td><\/tr>\n<tr><td>Yards per carry<\/td><td>4.1<\/td><td>3.2<\/td><\/tr>\n<tr><td>Passer rating<\/td><td>69.4<\/td><td>87.7<\/td><\/tr>\n<tr><td>Touchdowns<\/td><td>2.0<\/td><td>1.8<\/td><\/tr>\n<tr><td>Third-down conversion<\/td><td>39.8%<\/td><td>36.2%<\/td><\/tr>\n<tr><td>Red-zone conversion<\/td><td>60.0%<\/td><td>40.0%<\/td><\/tr>\n<tr><td>Sacks conceded \/ recorded<\/td><td>2.7<\/td><td>1.8<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n<h3>Jaguars attack against the Colts defense<\/h3>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Per game<\/th><th>Jaguars offense<\/th><th>Colts allow<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Passing yards<\/td><td>234.8<\/td><td>215.9<\/td><\/tr>\n<tr><td>Rushing yards<\/td><td>112.8<\/td><td>124.4<\/td><\/tr>\n<tr><td>Yards per carry<\/td><td>4.1<\/td><td>4.8<\/td><\/tr>\n<tr><td>Passer rating<\/td><td>106.2<\/td><td>97.4<\/td><\/tr>\n<tr><td>Touchdowns<\/td><td>3.0<\/td><td>2.6<\/td><\/tr>\n<tr><td>Third-down conversion<\/td><td>47.9%<\/td><td>30.0%<\/td><\/tr>\n<tr><td>Red-zone conversion<\/td><td>66.7%<\/td><td>60.0%<\/td><\/tr>\n<tr><td>Sacks conceded \/ recorded<\/td><td>1.7<\/td><td>1.9<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Jacksonville have conceded 11 touchdowns in six games, behind only Minnesota and Kansas City, and allow 40.0% in the red zone.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Colts vs Jaguars quarterback matchup<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Trevor Lawrence has 14 touchdown passes to four interceptions at 106.2. Daniel Jones has four to seven at 69.4, the second-lowest team rating in the NFL.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><thead><tr><th>Team<\/th><th>Quarterback<\/th><th>Last game<\/th><th>Season to date<\/th><\/tr><\/thead><tbody><tr><td>Colts<\/td><td>Daniel Jones<\/td><td>13\/22, 108 yds, 0 TD, 1 INT, 52.8 rtg<\/td><td>143\/240, 1398 yds, 4 TD, 7 INT, 69.4 rtg (7 games)<\/td><\/tr><tr><td>Jaguars<\/td><td>Trevor Lawrence<\/td><td>24\/41, 306 yds, 4 TD, 1 INT, 104.3 rtg<\/td><td>120\/184, 1480 yds, 14 TD, 4 INT, 106.2 rtg (6 games)<\/td><\/tr><\/tbody><\/table><figcaption>Last game is Week 7 (Week 6 for Jacksonville, who was idle). Season figures are 2026 to date, with games played in brackets.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Colts vs Jaguars injury report and team news<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Jacksonville concede 3.23 yards a carry, the lowest figure in the NFL.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Jacksonville allow 40.0% of red-zone trips to be converted, the fourth-best rate in the league.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Indianapolis rate 69.4 through the air, second-lowest in the NFL, and have conceded 19 sacks.<\/p>\n\n\n\n<!-- SQ_NFL_INJ_START -->\n\n<style>\n.sq-ninj{border:1px solid #123f5c;border-radius:14px;overflow:hidden;margin:24px 0;font-family:'Bricolage Grotesque',system-ui,-apple-system,sans-serif;background:#0a2540;color:#e8f0f7}\n.sq-ninj__head{display:flex;align-items:baseline;justify-content:space-between;gap:10px;padding:13px 16px;background:#06182b;font-weight:800;font-size:13px;letter-spacing:.4px;text-transform:uppercase;color:#fff;border-bottom:1px solid #123f5c}\n.sq-ninj__head span{font-size:11px;font-weight:600;letter-spacing:0;text-transform:none;color:rgba(232,240,247,.6)}\n.sq-ninj__cols{display:flex;flex-wrap:wrap}\n.sq-ninj__col{flex:1 1 260px;padding:14px 16px}\n.sq-ninj__col+.sq-ninj__col{border-left:1px solid #123f5c}\n.sq-ninj__team{display:flex;align-items:center;gap:9px;font-weight:800;font-size:14px;color:#fff;margin-bottom:10px}\n.sq-ninj__team img{width:24px;height:24px;object-fit:contain}\n.sq-ninj__row{display:flex;align-items:center;gap:8px;padding:6px 0;border-top:1px solid rgba(255,255,255,.06);font-size:13.5px}\n.sq-ninj__nm{flex:1;min-width:0;color:#fff;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}\n.sq-ninj__pos{flex:0 0 auto;color:rgba(232,240,247,.55);font-size:11px;font-weight:700}\n.sq-ninj__inj{flex:0 0 auto;color:rgba(232,240,247,.5);font-size:11px}\n.sq-ninj__st{flex:0 0 auto;font-size:10.5px;font-weight:800;letter-spacing:.04em;text-transform:uppercase;padding:3px 9px;border-radius:999px}\n.sq-ninj__st--out{background:rgba(255,106,90,.16);color:#FF6A5A}\n.sq-ninj__st--doubt{background:rgba(255,194,75,.16);color:#FFC24B}\n.sq-ninj__st--ques{background:rgba(232,240,247,.1);color:rgba(232,240,247,.8)}\n.sq-ninj__st--lt{background:rgba(160,180,200,.14);color:rgba(232,240,247,.82);border:1px solid rgba(232,240,247,.18)}\n.sq-ninj__lt{margin-top:11px;padding-top:9px;border-top:1px solid rgba(255,255,255,.12)}\n.sq-ninj__lt-h{font-size:10px;font-weight:800;letter-spacing:.06em;text-transform:uppercase;color:rgba(232,240,247,.5);margin-bottom:3px}\n.sq-ninj__none{font-size:13px;color:rgba(232,240,247,.55);padding:4px 0}\n@media(max-width:520px){.sq-ninj__col+.sq-ninj__col{border-left:0;border-top:1px solid #123f5c}}\n<\/style><div class=\"sq-ninj\"><div class=\"sq-ninj__head\">Injury report &middot; Week 8<span>Official game-status report &mdash; updates through the week<\/span><\/div><div class=\"sq-ninj__cols\"><div class=\"sq-ninj__col\"><div class=\"sq-ninj__team\"><img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/IND.png\" alt=\"IND\" loading=\"lazy\" width=\"24\" height=\"24\">Indianapolis Colts<\/div><div class=\"sq-ninj__none\">No game-status designations filed yet.<\/div><div class=\"sq-ninj__lt\"><div class=\"sq-ninj__lt-h\">Out long-term<\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Cam Taylor-Britt<\/span><span class=\"sq-ninj__pos\">CB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Cameron Mitchell<\/span><span class=\"sq-ninj__pos\">CB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Arden Key<\/span><span class=\"sq-ninj__pos\">DE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Micheal Clemons<\/span><span class=\"sq-ninj__pos\">DE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Carson Towt<\/span><span class=\"sq-ninj__pos\">TE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Alec Pierce<\/span><span class=\"sq-ninj__pos\">WR<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">D.J. Montgomery<\/span><span class=\"sq-ninj__pos\">WR<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><\/div><\/div><div class=\"sq-ninj__col\"><div class=\"sq-ninj__team\"><img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/JAC.png\" alt=\"JAC\" loading=\"lazy\" width=\"24\" height=\"24\">Jacksonville Jaguars<\/div><div class=\"sq-ninj__none\">No game-status designations filed yet.<\/div><div class=\"sq-ninj__lt\"><div class=\"sq-ninj__lt-h\">Out long-term<\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">B.J. Green II<\/span><span class=\"sq-ninj__pos\">DE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Zach Durfee<\/span><span class=\"sq-ninj__pos\">DE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Jared Bartlett<\/span><span class=\"sq-ninj__pos\">LB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Parker Hughes<\/span><span class=\"sq-ninj__pos\">LB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Anton Harrison<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Garrett DiGiorgio<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Patrick Mekari<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Sam Mustipher<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Caleb Ransaw<\/span><span class=\"sq-ninj__pos\">SAF<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><\/div><\/div><\/div><\/div>\n\n<!-- SQ_NFL_INJ_END -->\n\n\n\n<h2 class=\"wp-block-heading\">The best run defense nobody is talking about<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Three point two three yards a carry conceded \u2014 the best mark in the NFL \u2014 with 40.0% allowed in the red zone and 11 touchdowns given up in six games.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">They score too: a 106.2 team passer rating and Trevor Lawrence on 14 touchdown passes to four interceptions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Indianapolis are not equipped for it. Daniel Jones has thrown seven interceptions to four touchdowns, the Colts rate 69.4, and they have conceded 19 sacks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Players to watch<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Trevor Lawrence (JAC, QB):<\/strong> 1,480 passing yards and 14 touchdowns at 106.2.<\/li>\n<li><strong>Brian Thomas Jr. (JAC, WR):<\/strong> The first read in an offense converting 47.9% on third down.<\/li>\n<li><strong>Jonathan Taylor (IND, RB):<\/strong> 823 rushing yards at 4.12 a carry.<\/li>\n<li><strong>Tyler Warren (IND, TE):<\/strong> A central target in a passing game rating 69.4.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to watch Colts vs Jaguars<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Kickoff is 1:00 PM ET on Sunday, November 1 at EverBank Stadium, which is 12:00 PM CT and 10:00 AM PT. CBS has the regional broadcast.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-fixed-layout\">\n<thead>\n<tr><th>Detail<\/th><th>Colts vs Jaguars<\/th><\/tr>\n<\/thead>\n<tbody>\n<tr><td><strong>Date<\/strong><\/td><td>Sunday, November 1, 2026<\/td><\/tr>\n<tr><td><strong>Kickoff<\/strong><\/td><td>1:00 PM ET \/ 12:00 PM CT \/ 10:00 AM PT<\/td><\/tr>\n<tr><td><strong>Venue<\/strong><\/td><td>EverBank Stadium, Jacksonville, FL<\/td><\/tr>\n<tr><td><strong>TV<\/strong><\/td><td>CBS<\/td><\/tr>\n<tr><td><strong>Live stream<\/strong><\/td><td>NFL+ \/ Paramount+<\/td><\/tr>\n<tr><td><strong>Week<\/strong><\/td><td>Week 8, 2026 NFL season<\/td><\/tr>\n<\/tbody>\n<\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Colts vs Jaguars prediction and score projection<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Jacksonville win 27-16. The Jaguars have the best run defense in the league and the Colts have the second-worst passing game, which is a short route to a comfortable afternoon.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Signal&#8217;s live read on this game updates through the week.<\/p>\n\n\n\n<h2>Every Week 8 game, previewed<\/h2>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Kickoff (ET)<\/th><th>Game<\/th><th>Our prediction<\/th><th>Preview<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Thu 8:15 PM<\/td><td>Panthers @ Packers<\/td><td>Packers 27-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/panthers-vs-packers-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Cardinals @ Cowboys<\/td><td>Cowboys 27-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/cardinals-vs-cowboys-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Falcons @ Buccaneers<\/td><td>Buccaneers 24-21<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/falcons-vs-buccaneers-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Ravens @ Bills<\/td><td>Bills 27-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/ravens-vs-bills-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Browns @ Steelers<\/td><td>Steelers 23-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/browns-vs-steelers-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td><strong>Colts @ Jaguars<\/strong><\/td><td>Jaguars 27-16<\/td><td><em>You are here<\/em><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Raiders @ Jets<\/td><td>Raiders 23-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/raiders-vs-jets-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Vikings @ Lions<\/td><td>Vikings 24-21<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/vikings-vs-lions-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 2:00 PM<\/td><td>Titans @ Bengals<\/td><td>Bengals 30-13<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/titans-vs-bengals-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 5:05 PM<\/td><td>Chargers @ Rams<\/td><td>Rams 26-16<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/chargers-vs-rams-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 5:25 PM<\/td><td>Chiefs @ Broncos<\/td><td>Chiefs 27-24<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/chiefs-vs-broncos-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 5:25 PM<\/td><td>Patriots @ Dolphins<\/td><td>Patriots 26-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/patriots-vs-dolphins-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 9:20 PM<\/td><td>Eagles @ Commanders<\/td><td>Eagles 20-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/eagles-vs-commanders-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<tr><td>Mon 9:15 PM<\/td><td>Bears @ Seahawks<\/td><td>Seahawks 24-21<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/bears-vs-seahawks-prediction-picks-odds-week-8\/\">Read<\/a><\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"\/us\/nfl\/picks\/\">NFL predictions for the round<\/a> and <a href=\"\/us\/nfl\/\">our NFL hub<\/a> carry the rest of the card. The outright markets are priced in <a href=\"\/us\/outright-markets\/afc-championship-odds\/\">who wins the AFC<\/a>. For the player side of this game, see <a href=\"\/us\/nfl\/props\/\">player prop betting<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Colts vs Jaguars FAQ<\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-indjac-1\"><strong class=\"schema-faq-question\">Who is favored, the Colts or the Jaguars?<\/strong> <p class=\"schema-faq-answer\">Jacksonville, clearly. Our Signal model has the Jaguars as strong favorites and the live number is in the Signal card on this page. Jacksonville are 4-2 at +50; Indianapolis are 2-5 at -26.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-indjac-2\"><strong class=\"schema-faq-question\">What time is Colts vs Jaguars?<\/strong> <p class=\"schema-faq-answer\">1:00 PM ET on Sunday, November 1 at EverBank Stadium, which is 12:00 PM CT and 10:00 AM PT.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-indjac-3\"><strong class=\"schema-faq-question\">Which team has the best run defense?<\/strong> <p class=\"schema-faq-answer\">Jacksonville, conceding 3.23 yards a carry \u2014 the lowest figure in the NFL.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-indjac-4\"><strong class=\"schema-faq-question\">Are Jacksonville back home?<\/strong> <p class=\"schema-faq-answer\">Yes. This is their first game at EverBank after back-to-back home games in London.<\/p><\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><em>21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jacksonville concede 3.23 yards a carry, the best run defense in the NFL, and have given up 11 touchdowns in six games. Our Colts vs Jaguars prediction sends a 69.4 passing game at them. The Jacksonville Jaguars are 4-2 at +50 and back at EverBank after two home games in London. The Indianapolis Colts are&#8230;<\/p>\n","protected":false},"author":394,"featured_media":82545,"menu_order":0,"template":"","meta":{"_acf_changed":false,"_yoast_wpseo_focuskw":"colts vs jaguars prediction","_yoast_wpseo_title":"Colts vs Jaguars Prediction, Picks & Odds | Squawka","_yoast_wpseo_metadesc":"Colts vs Jaguars prediction, picks and odds for EverBank Stadium, where Jacksonville have the best run defense in the NFL and the Colts are 2-5.","footnotes":""},"tags":[358,360,350],"class_list":["post-82560","nfl-news","type-nfl-news","status-publish","has-post-thumbnail","hentry","tag-indianapolis-colts","tag-jacksonville-jaguars","tag-nfl"],"acf":{"external_featured_image_url":"","hide_featured_image_pattern":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Colts vs Jaguars Prediction, Picks &amp; Odds | Squawka<\/title>\n<meta name=\"description\" content=\"Colts vs Jaguars prediction, picks and odds for EverBank Stadium, where Jacksonville have the best run defense in the NFL and the Colts are 2-5.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/colts-vs-jaguars-prediction-picks-odds-week-8\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Colts vs Jaguars Prediction, Picks &amp; 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We publish match previews, tactical analysis, player and team stats, outright odds, betting tips, streaming guides and long-form features for a committed football audience. Founded in the UK and part of OneTwenty Group, Squawka now runs localised editions for the UK (squawka.com\\\/en\\\/), United States (squawka.com\\\/us\\\/), Mexican-Spanish (squawka.com\\\/us-es\\\/), Ireland, Netherlands, Nigeria, Kenya, Uganda, South Africa and Ghana. Each edition is editorially tailored to its market, with locale-specific competition focus, operator compliance and commercial partnerships. 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