{"id":70389,"date":"2026-10-13T13:01:26","date_gmt":"2026-10-13T17:01:26","guid":{"rendered":"https:\/\/www.squawka.com\/us\/?post_type=nfl-news&#038;p=70389"},"modified":"2026-10-13T13:01:26","modified_gmt":"2026-10-13T17:01:26","slug":"cardinals-vs-rams-prediction-picks-odds-week-6","status":"publish","type":"nfl-news","link":"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/cardinals-vs-rams-prediction-picks-odds-week-6\/","title":{"rendered":"Cardinals vs Rams Prediction, Picks &#038; Odds"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Arizona have conceded 21 touchdowns in five games, more than any team in the NFL, and traded Marvin Harrison Jr. to Houston on Sunday. Our <strong>Cardinals vs Rams prediction<\/strong> finds them at their lowest point of the season.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/www.squawka.com\/us\/nfl\/teams\/los-angeles-rams\/\">Los Angeles Rams<\/a> are 2-3 but have thrown for 1,538 yards, more than any team in the league. The <a href=\"https:\/\/www.squawka.com\/us\/nfl\/teams\/arizona-cardinals\/\">Arizona Cardinals<\/a> are 1-4 with a -54 point differential, the worst figure among the 28 teams playing this week.<\/p>\n\n\n\n<!-- SQ_NFL_SIG_START -->\n\n<style>\n.sq-nsig{position:relative;overflow:hidden;border-radius:18px;margin:28px 0;isolation:isolate;background:radial-gradient(70% 90% at 18% 0%,rgba(47,230,201,.14) 0%,rgba(47,230,201,0) 60%),linear-gradient(135deg,#0a2540 0%,#06182b 60%,#040f1d 100%);box-shadow:0 18px 44px rgba(4,15,29,.5);font-family:'Bricolage 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a{color:#2FE6C9;text-decoration:underline}\n@media(max-width:560px){.sq-nsig__inner{padding:22px 16px}.sq-nsig__cmp{gap:10px}.sq-nsig__verd{min-width:0}.sq-nsig__name{font-size:14px}}\n.sq-nsig__geo-r{position:absolute;width:0;height:0;opacity:0;pointer-events:none}\n.sq-nsig__geo-tabs{display:inline-flex;border:1px solid rgba(47,230,201,.4);border-radius:999px;overflow:hidden;margin:0 0 14px}\n.sq-nsig__geo-tab{cursor:pointer;padding:6px 15px;font-size:11px;font-weight:800;letter-spacing:.08em;text-transform:uppercase;color:rgba(232,240,247,.6)}\n.sq-nsig__geo-a{display:contents}.sq-nsig__geo-b{display:none}\n.sq-nsig__geo-r--a:checked~.sq-nsig__geo-tabs .sq-nsig__geo-tab--a,.sq-nsig__geo-r--b:checked~.sq-nsig__geo-tabs .sq-nsig__geo-tab--b{background:#2FE6C9;color:#04121f}\n.sq-nsig__geo-r--b:checked~.sq-nsig__cards .sq-nsig__geo-a,.sq-nsig__geo-r--b:checked~.sq-nsig__cta-row .sq-nsig__geo-a{display:none}\n.sq-nsig__geo-r--b:checked~.sq-nsig__cards .sq-nsig__geo-b,.sq-nsig__geo-r--b:checked~.sq-nsig__cta-row .sq-nsig__geo-b{display:contents}\n<\/style>\n<div class=\"sq-nsig\"><div class=\"sq-nsig__inner\"><span class=\"sq-nsig__tag\"><span class=\"dot\"><\/span>Squawka Signal &middot; Model vs market<\/span><h3 class=\"sq-nsig__title\">Arizona Cardinals @ Los Angeles Rams<\/h3><p class=\"sq-nsig__meta\">Week 6 &middot; Sun Oct 18, 4:05 PM ET. Our Signal model makes the <b>Los Angeles Rams<\/b> favorites by about <b>11<\/b> points, a 84% win probability.<\/p><div class=\"sq-nsig__cards\"><div class=\"sq-nsig__card\"><div class=\"sq-nsig__sum\"><img decoding=\"async\" class=\"sq-nsig__crest\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/ARI.png\" alt=\"ARI\" loading=\"lazy\" width=\"30\" height=\"30\"><span class=\"sq-nsig__name\">Arizona Cardinals<\/span><span class=\"sq-nsig__cmp\"><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Squawka<\/span><span class=\"sq-nsig__cmp-sig\">16%<\/span><\/span><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Market<\/span><span class=\"sq-nsig__cmp-mkt\">13%<\/span><\/span><span class=\"sq-nsig__verd sq-nsig__verd--val\">&#9650; Value<\/span><\/span><\/div><\/div><div class=\"sq-nsig__card\"><div class=\"sq-nsig__sum\"><img decoding=\"async\" class=\"sq-nsig__crest\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/LA.png\" alt=\"LA\" loading=\"lazy\" width=\"30\" height=\"30\"><span class=\"sq-nsig__name\">Los Angeles Rams<\/span><span class=\"sq-nsig__cmp\"><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Squawka<\/span><span class=\"sq-nsig__cmp-sig\">84%<\/span><\/span><span class=\"sq-nsig__cmp-c\"><span class=\"sq-nsig__cmp-k\">Market<\/span><span class=\"sq-nsig__cmp-mkt\">87%<\/span><\/span><span class=\"sq-nsig__verd sq-nsig__verd--lay\">&#9660; Slight lay<\/span><\/span><\/div><\/div><\/div><div class=\"sq-nsig__mc\"><span class=\"sq-nsig__mc-k\">Projected line<\/span><span class=\"sq-nsig__mc-v\">Los Angeles Rams -11<\/span><\/div><div class=\"sq-nsig__mc\"><span class=\"sq-nsig__mc-k\">Against the spread<\/span><span class=\"sq-nsig__mc-v\">Arizona Cardinals +13 &mdash; model Los Angeles Rams -11 vs market Los Angeles Rams -13<\/span><\/div><div class=\"sq-nsig__mc\"><span class=\"sq-nsig__mc-k\">Value<\/span><span class=\"sq-nsig__mc-v\">Arizona Cardinals &mdash; model 16% vs market 13%<\/span><\/div><div class=\"sq-nsig__cta-row\" style=\"margin-top:14px\"><a class=\"sq-nsig__cta2\" href=\"https:\/\/www.squawka.com\/us\/go\/kalshi?q=us-all-all-wof-s-spo\" rel=\"sponsored nofollow\" target=\"_blank\">Kalshi<\/a><a class=\"sq-nsig__cta2\" href=\"https:\/\/www.squawka.com\/us\/go\/polymarket?q=us-sg1-all-wof-s-spo\" rel=\"sponsored nofollow\" target=\"_blank\">Polymarket<\/a><a class=\"sq-nsig__cta2\" href=\"https:\/\/www.squawka.com\/us\/go\/prophet-x?q=us-sg1-all-wof-s-spo\" rel=\"sponsored nofollow\" target=\"_blank\">ProphetX<\/a><\/div><p class=\"sq-nsig__foot\">Squawka Signal is our model&#8217;s read against devigged market prices, updated after every result &mdash; not betting advice. <a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/nfl-signal-methodology\/\">How the NFL Signal works<\/a>. 21+. Play responsibly. 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class=\"sqp\" id=\"sqp-arila\">\n<div class=\"sqp__wrap\">\n<span class=\"sqp__kick\">Week 6 &middot; Editorial pick<\/span>\n<h2 class=\"sqp__ttl\">Cardinals vs Rams: our editor&#8217;s props<\/h2>\n<p class=\"sqp__sub\" data-props=\"2\">Two editor&#8217;s calls on this game, alongside the live Signal numbers.<\/p>\n<div class=\"sqp__crests\">\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/ARI.png\" alt=\"Cardinals\" loading=\"lazy\" width=\"28\" height=\"28\">\n<span class=\"sqp__at\">AT<\/span>\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/LA.png\" alt=\"Rams\" loading=\"lazy\" width=\"28\" height=\"28\">\n<\/div>\n<h3 class=\"sqp__h3\">Our props<\/h3>\n<div class=\"sqp__list\">\n<div class=\"sqp__row\" data-market=\"Total\" data-selection=\"Over 46.5 points\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Total<\/span><span class=\"sqp__pk\">Over 46.5 points<\/span><span class=\"sqp__why\">Arizona concede a 117.3 opponent passer rating and 76.5% of red-zone trips, both among the worst in the league. The Rams lead the NFL in passing yards.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 3 of 5\">&#9733;&#9733;&#9733;<span class=\"o\">&#9734;&#9734;<\/span><\/span><span class=\"sqp__lab\">3\/5 confidence<\/span><\/div>\n<\/div>\n<div class=\"sqp__row\" data-market=\"Player prop\" data-selection=\"Davante Adams 75+ receiving yards\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Player prop<\/span><span class=\"sqp__pk\">Davante Adams 75+ receiving yards<\/span><span class=\"sqp__why\">Adams has 441 receiving yards, sixth in the NFL. Arizona concede a 117.3 opponent passer rating, the worst mark in the league, and have allowed 21 touchdowns.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 3 of 5\">&#9733;&#9733;&#9733;<span class=\"o\">&#9734;&#9734;<\/span><\/span><span class=\"sqp__lab\">3\/5 confidence<\/span><\/div>\n<\/div>\n<\/div>\n<p class=\"sqp__foot\">An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.<\/p>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Cardinals vs Rams: 2026 form so far<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The league&#8217;s most productive passing game against a secondary conceding a 117.3 rating. The table sets each attack against what the other defense has conceded.<\/p>\n\n\n\n<h3>Cardinals attack against the Rams defense<\/h3>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Per game<\/th><th>Cardinals offense<\/th><th>Rams allow<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Passing yards<\/td><td>209.6<\/td><td>156.8<\/td><\/tr>\n<tr><td>Rushing yards<\/td><td>91.6<\/td><td>128.4<\/td><\/tr>\n<tr><td>Yards per carry<\/td><td>3.8<\/td><td>4.6<\/td><\/tr>\n<tr><td>Passer rating<\/td><td>85.4<\/td><td>78.1<\/td><\/tr>\n<tr><td>Touchdowns<\/td><td>2.4<\/td><td>2.6<\/td><\/tr>\n<tr><td>Third-down conversion<\/td><td>40.5%<\/td><td>32.8%<\/td><\/tr>\n<tr><td>Red-zone conversion<\/td><td>61.1%<\/td><td>64.7%<\/td><\/tr>\n<tr><td>Sacks conceded \/ recorded<\/td><td>2.4<\/td><td>1.6<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n<h3>Rams attack against the Cardinals defense<\/h3>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Per game<\/th><th>Rams offense<\/th><th>Cardinals allow<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Passing yards<\/td><td>307.6<\/td><td>236.8<\/td><\/tr>\n<tr><td>Rushing yards<\/td><td>116.8<\/td><td>126.6<\/td><\/tr>\n<tr><td>Yards per carry<\/td><td>4.6<\/td><td>4.4<\/td><\/tr>\n<tr><td>Passer rating<\/td><td>88.2<\/td><td>117.3<\/td><\/tr>\n<tr><td>Touchdowns<\/td><td>3.0<\/td><td>4.2<\/td><\/tr>\n<tr><td>Third-down conversion<\/td><td>44.6%<\/td><td>42.1%<\/td><\/tr>\n<tr><td>Red-zone conversion<\/td><td>65.0%<\/td><td>76.5%<\/td><\/tr>\n<tr><td>Sacks conceded \/ recorded<\/td><td>1.4<\/td><td>2.2<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n<p><em>Figures are season to date, across 5 games.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Twenty-one touchdowns conceded and a 117.3 opponent passer rating. Arizona have the worst pass defense in football, and the Rams throw more than anyone.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Cardinals vs Rams quarterback matchup<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Los Angeles rate 88.2 through the air to Arizona&#8217;s 85.4, though the Rams have thrown 219 times to the Cardinals&#8217; 200.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><thead><tr><th>Team<\/th><th>Quarterback<\/th><th>Last game<\/th><th>Season to date<\/th><\/tr><\/thead><tbody><tr><td>Cardinals<\/td><td>Jacoby Brissett<\/td><td>38\/52, 280 yds, 2 TD, 0 INT, 98.2 rtg<\/td><td>103\/152, 818 yds, 6 TD, 4 INT, 83.2 rtg (4 games)<\/td><\/tr><tr><td>Rams<\/td><td>Matthew Stafford<\/td><td>30\/55, 390 yds, 2 TD, 2 INT, 74.1 rtg<\/td><td>99\/162, 1189 yds, 6 TD, 6 INT, 80.5 rtg (4 games)<\/td><\/tr><\/tbody><\/table><figcaption>Last game is Week 3. Season figures are 2026 to date, with games played in brackets.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Cardinals vs Rams injury report and team news<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Marvin Harrison Jr. was traded to Houston on 11 October and is no longer on the Arizona roster.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Los Angeles have thrown for 1,538 yards, more than any team in the NFL.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Arizona have conceded 21 touchdowns in five games, more than any other team.<\/p>\n\n\n\n<!-- SQ_NFL_INJ_START -->\n\n<style>\n.sq-ninj{border:1px solid #123f5c;border-radius:14px;overflow:hidden;margin:24px 0;font-family:'Bricolage Grotesque',system-ui,-apple-system,sans-serif;background:#0a2540;color:#e8f0f7}\n.sq-ninj__head{display:flex;align-items:baseline;justify-content:space-between;gap:10px;padding:13px 16px;background:#06182b;font-weight:800;font-size:13px;letter-spacing:.4px;text-transform:uppercase;color:#fff;border-bottom:1px solid #123f5c}\n.sq-ninj__head span{font-size:11px;font-weight:600;letter-spacing:0;text-transform:none;color:rgba(232,240,247,.6)}\n.sq-ninj__cols{display:flex;flex-wrap:wrap}\n.sq-ninj__col{flex:1 1 260px;padding:14px 16px}\n.sq-ninj__col+.sq-ninj__col{border-left:1px solid #123f5c}\n.sq-ninj__team{display:flex;align-items:center;gap:9px;font-weight:800;font-size:14px;color:#fff;margin-bottom:10px}\n.sq-ninj__team img{width:24px;height:24px;object-fit:contain}\n.sq-ninj__row{display:flex;align-items:center;gap:8px;padding:6px 0;border-top:1px solid rgba(255,255,255,.06);font-size:13.5px}\n.sq-ninj__nm{flex:1;min-width:0;color:#fff;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}\n.sq-ninj__pos{flex:0 0 auto;color:rgba(232,240,247,.55);font-size:11px;font-weight:700}\n.sq-ninj__inj{flex:0 0 auto;color:rgba(232,240,247,.5);font-size:11px}\n.sq-ninj__st{flex:0 0 auto;font-size:10.5px;font-weight:800;letter-spacing:.04em;text-transform:uppercase;padding:3px 9px;border-radius:999px}\n.sq-ninj__st--out{background:rgba(255,106,90,.16);color:#FF6A5A}\n.sq-ninj__st--doubt{background:rgba(255,194,75,.16);color:#FFC24B}\n.sq-ninj__st--ques{background:rgba(232,240,247,.1);color:rgba(232,240,247,.8)}\n.sq-ninj__st--lt{background:rgba(160,180,200,.14);color:rgba(232,240,247,.82);border:1px solid rgba(232,240,247,.18)}\n.sq-ninj__lt{margin-top:11px;padding-top:9px;border-top:1px solid rgba(255,255,255,.12)}\n.sq-ninj__lt-h{font-size:10px;font-weight:800;letter-spacing:.06em;text-transform:uppercase;color:rgba(232,240,247,.5);margin-bottom:3px}\n.sq-ninj__none{font-size:13px;color:rgba(232,240,247,.55);padding:4px 0}\n@media(max-width:520px){.sq-ninj__col+.sq-ninj__col{border-left:0;border-top:1px solid #123f5c}}\n<\/style><div class=\"sq-ninj\"><div class=\"sq-ninj__head\">Injury report &middot; Week 6<span>Official game-status report &mdash; updates through the week<\/span><\/div><div class=\"sq-ninj__cols\"><div class=\"sq-ninj__col\"><div class=\"sq-ninj__team\"><img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/ARI.png\" alt=\"ARI\" loading=\"lazy\" width=\"24\" height=\"24\">Arizona Cardinals<\/div><div class=\"sq-ninj__none\">No game-status designations filed yet.<\/div><div class=\"sq-ninj__lt\"><div class=\"sq-ninj__lt-h\">Out long-term<\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Will Johnson<\/span><span class=\"sq-ninj__pos\">CB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Kaleb Proctor<\/span><span class=\"sq-ninj__pos\">DL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Zach Carter<\/span><span class=\"sq-ninj__pos\">DL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Chase Bisontis<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Isaiah Adams<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Paris Johnson Jr.<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">James Conner<\/span><span class=\"sq-ninj__pos\">RB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Trey Benson<\/span><span class=\"sq-ninj__pos\">RB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Joey Blount<\/span><span class=\"sq-ninj__pos\">SAF<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Kitan Crawford<\/span><span class=\"sq-ninj__pos\">SAF<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Hunter Long<\/span><span class=\"sq-ninj__pos\">TE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Jameson Geers<\/span><span class=\"sq-ninj__pos\">TE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Tip Reiman<\/span><span class=\"sq-ninj__pos\">TE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">PUP<\/span><\/div><\/div><\/div><div class=\"sq-ninj__col\"><div class=\"sq-ninj__team\"><img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/LA.png\" alt=\"LA\" loading=\"lazy\" width=\"24\" height=\"24\">Los Angeles Rams<\/div><div class=\"sq-ninj__none\">No game-status designations filed yet.<\/div><div class=\"sq-ninj__lt\"><div class=\"sq-ninj__lt-h\">Out long-term<\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Justin Dedich<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Keagen Trost<\/span><span class=\"sq-ninj__pos\">OL<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Eddie Walls III<\/span><span class=\"sq-ninj__pos\">OLB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Keir Thomas<\/span><span class=\"sq-ninj__pos\">OLB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Myles Garrett<\/span><span class=\"sq-ninj__pos\">OLB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Matthew Caldwell<\/span><span class=\"sq-ninj__pos\">QB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Ronnie Rivers<\/span><span class=\"sq-ninj__pos\">RB<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><div class=\"sq-ninj__row\"><span class=\"sq-ninj__nm\">Terrance Ferguson<\/span><span class=\"sq-ninj__pos\">TE<\/span><span class=\"sq-ninj__st sq-ninj__st--lt\">IR<\/span><\/div><\/div><\/div><\/div><\/div>\n\n<!-- SQ_NFL_INJ_END -->\n\n\n\n<h2 class=\"wp-block-heading\">The worst pass defense in football<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A 117.3 opponent passer rating, 14 touchdown passes conceded and 76.5% of red-zone trips finished against them. Arizona have conceded 21 touchdowns in all, more than any team in the league.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Rams are the wrong opponent. Their 1,538 passing yards lead the league and Davante Adams has 441 of them, with Puka Nacua on 337 behind him.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Arizona lost Marvin Harrison Jr. on Sunday, which removes their best-known attacking player from a side that has been outscored by 54. Trey McBride&#8217;s 308 receiving yards now lead the team.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Players to watch<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Davante Adams (LA, WR):<\/strong> 441 receiving yards, sixth in the NFL.<\/li>\n<li><strong>Kyren Williams (LA, RB):<\/strong> 343 rushing yards behind the league&#8217;s busiest passing game.<\/li>\n<li><strong>Trey McBride (ARI, TE):<\/strong> 308 receiving yards, now Arizona&#8217;s leading target.<\/li>\n<li><strong>Jeremiyah Love (ARI, RB):<\/strong> 245 rushing yards for a side outscored by 54.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to watch Cardinals vs Rams<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Kickoff is 4:05 PM ET on Sunday, October 18 at SoFi Stadium, which is 3:05 PM CT and 1:05 PM PT. FOX has the regional broadcast.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-fixed-layout\">\n<thead>\n<tr><th>Detail<\/th><th>Cardinals vs Rams<\/th><\/tr>\n<\/thead>\n<tbody>\n<tr><td><strong>Date<\/strong><\/td><td>Sunday, October 18, 2026<\/td><\/tr>\n<tr><td><strong>Kickoff<\/strong><\/td><td>4:05 PM ET \/ 3:05 PM CT \/ 1:05 PM PT<\/td><\/tr>\n<tr><td><strong>Venue<\/strong><\/td><td>SoFi Stadium, Inglewood, CA<\/td><\/tr>\n<tr><td><strong>TV<\/strong><\/td><td>FOX<\/td><\/tr>\n<tr><td><strong>Live stream<\/strong><\/td><td>NFL+ \/ Fubo<\/td><\/tr>\n<tr><td><strong>Week<\/strong><\/td><td>Week 6, 2026 NFL season<\/td><\/tr>\n<\/tbody>\n<\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Cardinals vs Rams prediction and score projection<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Los Angeles win 30-20. The Rams throw more than anyone and Arizona cannot stop it, and the Cardinals are a weaker team this week than last.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The live line and our projected margin both update through the week.<\/p>\n\n\n\n<h2>Every Week 6 game, previewed<\/h2>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Kickoff (ET)<\/th><th>Game<\/th><th>Our prediction<\/th><th>Preview<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Thu 8:15 PM<\/td><td>Seahawks @ Broncos<\/td><td>Seahawks 24-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/seahawks-vs-broncos-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 9:30 AM<\/td><td>Texans @ Jaguars<\/td><td>Jaguars 27-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/texans-vs-jaguars-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Ravens @ Browns<\/td><td>Ravens 27-16<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/ravens-vs-browns-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Panthers @ Eagles<\/td><td>Panthers 24-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/panthers-vs-eagles-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Bears @ Falcons<\/td><td>Bears 23-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/bears-vs-falcons-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Saints @ Giants<\/td><td>Giants 26-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/saints-vs-giants-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Jets @ Patriots<\/td><td>Patriots 24-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/jets-vs-patriots-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Steelers @ Buccaneers<\/td><td>Steelers 23-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/steelers-vs-buccaneers-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Titans @ Colts<\/td><td>Colts 23-13<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/titans-vs-colts-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 4:05 PM<\/td><td><strong>Cardinals @ Rams<\/strong><\/td><td>Rams 30-20<\/td><td><em>You are here<\/em><\/td><\/tr>\n<tr><td>Sun 4:25 PM<\/td><td>Bills @ Raiders<\/td><td>Bills 30-27<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/bills-vs-raiders-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 4:25 PM<\/td><td>Chargers @ Chiefs<\/td><td>Chiefs 31-13<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/chargers-vs-chiefs-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 8:20 PM<\/td><td>Cowboys @ Packers<\/td><td>Packers 27-24<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/cowboys-vs-packers-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<tr><td>Mon 8:15 PM<\/td><td>Commanders @ 49ers<\/td><td>49ers 31-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/commanders-vs-49ers-prediction-picks-odds-week-6\/\">Read<\/a><\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">You can find <a href=\"\/us\/nfl\/picks\/\">our pick record<\/a> alongside <a href=\"\/us\/nfl\/\">our NFL hub<\/a>. The outright markets are priced in <a href=\"\/us\/outright-markets\/nfc-championship-odds\/\">the NFC board<\/a>. Player markets sit with <a href=\"\/us\/nfl\/props\/\">prop markets for this game<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Cardinals vs Rams FAQ<\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-arila-1\"><strong class=\"schema-faq-question\">Who is favored, the Cardinals or the Rams?<\/strong> <p class=\"schema-faq-answer\">Los Angeles, at home. The Rams are 2-3 at -1; Arizona are 1-4 at -54.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-arila-2\"><strong class=\"schema-faq-question\">What time is Cardinals vs Rams?<\/strong> <p class=\"schema-faq-answer\">4:05 PM ET on Sunday, October 18, at SoFi Stadium.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-arila-3\"><strong class=\"schema-faq-question\">Is Marvin Harrison Jr. still with Arizona?<\/strong> <p class=\"schema-faq-answer\">No. He was traded to Houston on 11 October.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-arila-4\"><strong class=\"schema-faq-question\">Which team has the worst pass defense?<\/strong> <p class=\"schema-faq-answer\">Arizona, conceding a 117.3 opponent passer rating &#8212; the worst in the NFL &#8212; and 21 touchdowns in total.<\/p><\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><em>21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Arizona have conceded 21 touchdowns in five games, more than any team in the NFL, and traded Marvin Harrison Jr. to Houston on Sunday. Our Cardinals vs Rams prediction finds them at their lowest point of the season. The Los Angeles Rams are 2-3 but have thrown for 1,538 yards, more than any team in&#8230;<\/p>\n","protected":false},"author":394,"featured_media":70388,"menu_order":0,"template":"","meta":{"_acf_changed":false,"_yoast_wpseo_focuskw":"cardinals vs rams prediction","_yoast_wpseo_title":"Cardinals vs Rams Prediction, Picks & Odds | Squawka","_yoast_wpseo_metadesc":"Cardinals vs Rams prediction, picks and odds for SoFi Stadium, where Arizona have conceded 21 touchdowns and traded away their best receiver.","footnotes":""},"tags":[375,354,350],"class_list":["post-70389","nfl-news","type-nfl-news","status-publish","has-post-thumbnail","hentry","tag-arizona-cardinals","tag-los-angeles-rams","tag-nfl"],"acf":{"external_featured_image_url":"","hide_featured_image_pattern":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Cardinals vs Rams Prediction, Picks &amp; Odds | Squawka<\/title>\n<meta name=\"description\" content=\"Cardinals vs Rams prediction, picks and odds for SoFi Stadium, where Arizona have conceded 21 touchdowns and traded away their best receiver.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/cardinals-vs-rams-prediction-picks-odds-week-6\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cardinals vs Rams Prediction, Picks &amp; 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