{"id":65587,"date":"2026-10-07T03:52:00","date_gmt":"2026-10-07T07:52:00","guid":{"rendered":"https:\/\/www.squawka.com\/us\/?post_type=nfl-news&#038;p=65587"},"modified":"2026-10-07T05:17:41","modified_gmt":"2026-10-07T09:17:41","slug":"lions-vs-cardinals-prediction-picks-odds-week-5","status":"publish","type":"nfl-news","link":"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/lions-vs-cardinals-prediction-picks-odds-week-5\/","title":{"rendered":"Lions vs Cardinals Prediction, Picks &#038; Odds"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Detroit have conceded 17 touchdowns, more than any team in the NFL, and allow opponents 52.8% on third down, also the worst mark in the league. Our <strong>Lions vs Cardinals prediction<\/strong> explains how they are still 2-2.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">They score. The <a href=\"https:\/\/www.squawka.com\/us\/nfl\/teams\/detroit-lions\/\">Detroit Lions<\/a> have 119 points and a 108.6 passer rating, and they have simply been outscoring the damage. The <a href=\"https:\/\/www.squawka.com\/us\/nfl\/teams\/arizona-cardinals\/\">Arizona Cardinals<\/a> are 1-3, have conceded 15 touchdowns of their own, and allow a 114.9 opponent rating.<\/p>\n\n\n\n<!-- SQ_NFL_SIGNAL -->\n\n\n\n<style>\n\/* Squawka NFL picks card - palette matched to the injected sq-nsig Signal units *\/\n.sqp{--cy:#2FE6C9;--val:#38D97A;--ovr:#FF6A5A;--fair:#FFC24B;--tx:#e8f0f7;--mut:rgba(232,240,247,.60);--line:rgba(255,255,255,.10);--gold:#FFC24B;position:relative;overflow:hidden;font-family:'Bricolage Grotesque',system-ui,-apple-system,Segoe UI,Roboto,sans-serif;color:var(--tx);max-width:960px;margin:14px auto 26px;border-radius:14px;background:linear-gradient(135deg,#0a2540 0%,#06182b 62%,#04121f 100%);box-shadow:0 14px 36px rgba(4,18,31,.34)}\n.sqp *{box-sizing:border-box}\n.sqp__wrap{padding:22px 26px 20px}\n.sqp__kick{display:inline-flex;align-items:center;gap:8px;font-size:11px;font-weight:800;letter-spacing:.14em;text-transform:uppercase;color:var(--cy)}\n.sqp__kick::before{content:'';width:7px;height:7px;border-radius:50%;background:var(--cy);box-shadow:0 0 9px 1px var(--cy)}\n.sqp__ttl{font-size:24px;font-weight:800;letter-spacing:-.3px;line-height:1.14;margin:12px 0 0;color:var(--tx)}\n.sqp__sub{margin:7px 0 0;font-size:14.5px;line-height:1.5;color:var(--mut);max-width:70ch}\n.sqp__crests{display:flex;align-items:center;gap:10px;margin-top:14px}\n.sqp__crests img{width:28px;height:28px;display:block}\n.sqp__at{font-size:12px;font-weight:700;color:var(--mut);letter-spacing:.1em}\n.sqp__h3{margin:20px 0 0;font-size:10.5px;font-weight:800;letter-spacing:.16em;text-transform:uppercase;color:var(--cy)}\n.sqp__list{margin-top:12px;border-top:1px solid var(--line)}\n.sqp__row{display:grid;grid-template-columns:1fr 126px;gap:14px;align-items:center;padding:14px 2px;border-bottom:1px solid var(--line)}\n.sqp__mkt{display:block;font-size:10px;font-weight:800;letter-spacing:.13em;text-transform:uppercase;color:var(--cy);margin-bottom:4px}\n.sqp__pk{font-size:15.5px;font-weight:800;line-height:1.25;color:var(--tx)}\n.sqp__top{display:inline-block;vertical-align:middle;margin-left:8px;font-size:9.5px;font-weight:800;letter-spacing:.08em;text-transform:uppercase;color:#3a2c00;background:var(--gold);padding:3px 7px;border-radius:5px}\n.sqp__why{display:block;margin-top:5px;font-size:13.5px;line-height:1.5;color:var(--mut)}\n.sqp__pr{text-align:center}\n.sqp__val{display:block;font-size:23px;font-weight:800;color:var(--cy);line-height:1;text-decoration:none}\na.sqp__val:hover{text-decoration:underline}\n.sqp__stars{display:block;font-size:15px;line-height:1;letter-spacing:1px;color:var(--gold)}\n.sqp__stars .o{opacity:.55}\n.sqp__lab{display:block;font-size:10px;letter-spacing:.06em;text-transform:uppercase;color:var(--mut);margin-top:4px}\n.sqp__verd{display:inline-block;margin-top:6px;font-size:10.5px;font-weight:800;letter-spacing:.04em;padding:2px 7px;border-radius:5px}\n.sqp__verd--val{color:var(--val);background:rgba(56,217,122,.12)}\n.sqp__verd--ovr{color:var(--ovr);background:rgba(255,106,90,.12)}\n.sqp__verd--fair{color:var(--fair);background:rgba(255,194,75,.12)}\n.sqp__approach{margin:14px 0 0;font-size:13.5px;line-height:1.55;color:var(--tx)}\n.sqp__foot{margin:16px 0 0;padding-top:13px;border-top:1px solid var(--line);font-size:11.5px;line-height:1.55;color:rgba(232,240,247,.5)}\n.sqp__foot a{color:var(--cy);font-weight:700;text-decoration:none;border-bottom:1px solid rgba(47,230,201,.35)}\n@media(max-width:640px){\n.sqp__wrap{padding:18px 15px 16px}\n.sqp__ttl{font-size:20px}\n.sqp__row{grid-template-columns:1fr 100px;gap:10px}\n.sqp__val{font-size:20px}\n}\n<\/style>\n<div class=\"sqp\" id=\"sqp-detari\">\n<div class=\"sqp__wrap\">\n<span class=\"sqp__kick\">Week 5 &middot; Editorial pick<\/span>\n<h2 class=\"sqp__ttl\">Lions vs Cardinals: our editor&#8217;s props<\/h2>\n<p class=\"sqp__sub\" data-props=\"2\">Two editorial selections to sit with the live Signal read below.<\/p>\n<div class=\"sqp__crests\">\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/DET.png\" alt=\"Lions\" loading=\"lazy\" width=\"28\" height=\"28\">\n<span class=\"sqp__at\">AT<\/span>\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/us\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/ARI.png\" alt=\"Cardinals\" loading=\"lazy\" width=\"28\" height=\"28\">\n<\/div>\n<h3 class=\"sqp__h3\">Our props<\/h3>\n<div class=\"sqp__list\">\n<div class=\"sqp__row\" data-market=\"Total\" data-selection=\"Over 48.5 points\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Total<\/span><span class=\"sqp__pk\">Over 48.5 points<\/span><span class=\"sqp__why\">Detroit allow 52.8% on third down and 82.4% in the red zone, both near the bottom of the league. Arizona concede a 114.9 opponent passer rating. Between them these defenses have given up 32 touchdowns in eight games.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 4 of 5\">&#9733;&#9733;&#9733;&#9733;<span class=\"o\">&#9734;<\/span><\/span><span class=\"sqp__lab\">4\/5 confidence<\/span><\/div>\n<\/div>\n<div class=\"sqp__row\" data-market=\"Player prop\" data-selection=\"Amon-Ra St. Brown 80+ receiving yards\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Player prop<\/span><span class=\"sqp__pk\">Amon-Ra St. Brown 80+ receiving yards<\/span><span class=\"sqp__why\">St. Brown has 303 receiving yards from 31 catches. Arizona have allowed 935 passing yards and a 114.9 rating, the second-highest figure in the NFL.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 3 of 5\">&#9733;&#9733;&#9733;<span class=\"o\">&#9734;&#9734;<\/span><\/span><span class=\"sqp__lab\">3\/5 confidence<\/span><\/div>\n<\/div>\n<\/div>\n<p class=\"sqp__foot\">An editorial call, not a Signal model output. 21+. Gambling Problem? Call 1-800-GAMBLER.<\/p>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Lions vs Cardinals: 2026 form so far<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Two defenses that have stopped very little, and one offense considerably better than the other. The table puts each attack against what the opposite side allows.<\/p>\n\n\n\n<h3>Lions attack against the Cardinals defense<\/h3>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Per game<\/th><th>Lions offense<\/th><th>Cardinals allow<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Passing yards<\/td><td>287.2<\/td><td>233.8<\/td><\/tr>\n<tr><td>Rushing yards<\/td><td>102.0<\/td><td>117.5<\/td><\/tr>\n<tr><td>Yards per carry<\/td><td>4.2<\/td><td>4.2<\/td><\/tr>\n<tr><td>Passer rating<\/td><td>108.6<\/td><td>114.9<\/td><\/tr>\n<tr><td>Touchdowns<\/td><td>3.5<\/td><td>3.8<\/td><\/tr>\n<tr><td>Third-down conversion<\/td><td>39.1%<\/td><td>45.5%<\/td><\/tr>\n<tr><td>Red-zone conversion<\/td><td>72.2%<\/td><td>69.2%<\/td><\/tr>\n<tr><td>Sacks conceded \/ recorded<\/td><td>2.0<\/td><td>2.0<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n<h3>Cardinals attack against the Lions defense<\/h3>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Per game<\/th><th>Cardinals offense<\/th><th>Lions allow<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Passing yards<\/td><td>194.2<\/td><td>304.0<\/td><\/tr>\n<tr><td>Rushing yards<\/td><td>100.5<\/td><td>119.8<\/td><\/tr>\n<tr><td>Yards per carry<\/td><td>3.9<\/td><td>4.4<\/td><\/tr>\n<tr><td>Passer rating<\/td><td>83.2<\/td><td>110.4<\/td><\/tr>\n<tr><td>Touchdowns<\/td><td>2.2<\/td><td>4.2<\/td><\/tr>\n<tr><td>Third-down conversion<\/td><td>39.3%<\/td><td>52.8%<\/td><\/tr>\n<tr><td>Red-zone conversion<\/td><td>57.1%<\/td><td>82.4%<\/td><\/tr>\n<tr><td>Sacks conceded \/ recorded<\/td><td>1.8<\/td><td>3.8<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n<p><em>Figures are season to date, across 4 games.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Seventeen touchdowns conceded is the most in the league, and a 52.8% third-down conversion rate against is also the worst. Detroit have covered it with points, which works until it meets a defense that can do the same.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lions vs Cardinals quarterback matchup<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Detroit rate 108.6 through the air to Arizona&#8217;s 83.2, a 25.4-point gap and the second widest in this week&#8217;s NFC games.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><thead><tr><th>Team<\/th><th>Quarterback<\/th><th>Last game<\/th><th>Season to date<\/th><\/tr><\/thead><tbody><tr><td>Lions<\/td><td>Jared Goff<\/td><td>25\/32, 269 yds, 2 TD, 0 INT, 122.5 rtg<\/td><td>109\/161, 1214 yds, 9 TD, 0 INT, 108.6 rtg (4 games)<\/td><\/tr><tr><td>Cardinals<\/td><td>Jacoby Brissett<\/td><td>38\/52, 280 yds, 2 TD, 0 INT, 98.2 rtg<\/td><td>103\/152, 818 yds, 6 TD, 4 INT, 83.2 rtg (4 games)<\/td><\/tr><\/tbody><\/table><figcaption>Last game is Week 3. Season figures are 2026 to date, with games played in brackets.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Lions vs Cardinals injury report and team news<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">James Conner is on injured reserve for Arizona, as is Trey Benson, leaving Jeremiyah Love to carry the backfield.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Aidan Hutchinson has three sacks in a Detroit front that has recorded 15, second-most in the NFL.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Trey McBride has 33 receptions for Arizona, third-most of any player in the league.<\/p>\n\n\n\n<!-- SQ_NFL_INJURIES -->\n\n\n\n<h2 class=\"wp-block-heading\">Two defenses that cannot get off the field<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Detroit&#8217;s offense is genuine. A 108.6 team passer rating, 1,149 passing yards, 14 touchdowns and a 72.2% red-zone conversion rate make them one of the better attacks in football, and Jahmyr Gibbs has 353 rushing yards on top of it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Their defense has been the opposite. Seventeen touchdowns and 1,216 passing yards conceded, a 52.8% third-down rate against, 82.4% of opponent red-zone trips finished. Fifteen sacks say the pass rush works; everything behind it has not.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Arizona are not equipped to punish that as much as they should be. They rate 83.2 through the air and have conceded 15 touchdowns themselves, so this becomes a question of which bad defense faces the better offense. On that, it is not close.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Players to watch<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Jahmyr Gibbs (DET, RB):<\/strong> 353 rushing yards, joint fifth in the NFL.<\/li>\n<li><strong>Amon-Ra St. Brown (DET, WR):<\/strong> 303 receiving yards from 31 catches, fifth in the league for receptions.<\/li>\n<li><strong>Trey McBride (ARI, TE):<\/strong> 33 receptions, third-most of any player in the NFL.<\/li>\n<li><strong>Michael Wilson (ARI, WR):<\/strong> 258 receiving yards from 25 catches for Arizona.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to watch Lions vs Cardinals<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Kickoff is 4:25 PM ET on Sunday, October 11 at State Farm Stadium, which is 3:25 PM CT and 1:25 PM PT. FOX has the regional broadcast.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-fixed-layout\">\n<thead>\n<tr><th>Detail<\/th><th>Lions vs Cardinals<\/th><\/tr>\n<\/thead>\n<tbody>\n<tr><td><strong>Date<\/strong><\/td><td>Sunday, October 11, 2026<\/td><\/tr>\n<tr><td><strong>Kickoff<\/strong><\/td><td>4:25 PM ET \/ 3:25 PM CT \/ 1:25 PM PT<\/td><\/tr>\n<tr><td><strong>Venue<\/strong><\/td><td>State Farm Stadium, Glendale, AZ<\/td><\/tr>\n<tr><td><strong>TV<\/strong><\/td><td>FOX<\/td><\/tr>\n<tr><td><strong>Live stream<\/strong><\/td><td>NFL+ \/ Fubo<\/td><\/tr>\n<tr><td><strong>Week<\/strong><\/td><td>Week 5, 2026 NFL season<\/td><\/tr>\n<\/tbody>\n<\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Lions vs Cardinals prediction and score projection<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Detroit win 27-20. The Lions concede more than anyone, but they also score more than Arizona can, and that has been enough in three of four games.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Signal&#8217;s live win probability for this game will move once the designations land.<\/p>\n\n\n\n<h2>Every Week 5 game, previewed<\/h2>\n<figure class=\"wp-block-table is-style-stripes\"><table>\n<thead><tr><th>Kickoff (ET)<\/th><th>Game<\/th><th>Our prediction<\/th><th>Preview<\/th><\/tr><\/thead>\n<tbody>\n<tr><td>Thu 8:15 PM<\/td><td>Buccaneers @ Cowboys<\/td><td>Cowboys 27-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/buccaneers-vs-cowboys-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 9:30 AM<\/td><td>Eagles @ Jaguars<\/td><td>Jaguars 24-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/eagles-vs-jaguars-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Bears @ Packers<\/td><td>Bears 24-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/bears-vs-packers-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Bengals @ Dolphins<\/td><td>Bengals 27-16<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/bengals-vs-dolphins-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Browns @ Jets<\/td><td>Browns 20-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/browns-vs-jets-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Texans @ Titans<\/td><td>Texans 19-16<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/texans-vs-titans-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Colts @ Steelers<\/td><td>Steelers 21-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/colts-vs-steelers-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Raiders @ Patriots<\/td><td>Raiders 23-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/raiders-vs-patriots-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Vikings @ Saints<\/td><td>Vikings 26-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/vikings-vs-saints-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 1:00 PM<\/td><td>Giants @ Commanders<\/td><td>Giants 24-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/giants-vs-commanders-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 4:05 PM<\/td><td>Broncos @ Chargers<\/td><td>Broncos 23-17<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/broncos-vs-chargers-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 4:25 PM<\/td><td><strong>Lions @ Cardinals<\/strong><\/td><td>Lions 27-20<\/td><td><em>You are here<\/em><\/td><\/tr>\n<tr><td>Sun 4:25 PM<\/td><td>49ers @ Seahawks<\/td><td>Seahawks 24-21<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/49ers-vs-seahawks-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Sun 8:20 PM<\/td><td>Ravens @ Falcons<\/td><td>Ravens 26-20<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/ravens-vs-falcons-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<tr><td>Mon 8:15 PM<\/td><td>Bills @ Rams<\/td><td>Bills 27-23<\/td><td><a href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/bills-vs-rams-prediction-picks-odds-week-5\/\">Read<\/a><\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">You can find <a href=\"\/us\/nfl\/picks\/\">NFL predictions for the round<\/a> alongside <a href=\"\/us\/nfl\/\">our NFL hub<\/a>. The outright markets are priced in <a href=\"\/us\/outright-markets\/nfc-championship-odds\/\">the NFC board<\/a>. We price the player markets in <a href=\"\/us\/nfl\/props\/\">prop markets for this game<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lions vs Cardinals FAQ<\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-detari-1\"><strong class=\"schema-faq-question\">Who is favored, the Lions or the Cardinals?<\/strong> <p class=\"schema-faq-answer\">Detroit. The Lions are 2-2 with 119 points scored; Arizona are 1-3 and have been outscored by 30.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-detari-2\"><strong class=\"schema-faq-question\">What time is Lions vs Cardinals?<\/strong> <p class=\"schema-faq-answer\">4:25 PM ET on Sunday, October 11, at State Farm Stadium.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-detari-3\"><strong class=\"schema-faq-question\">How bad is Detroit&#8217;s defense?<\/strong> <p class=\"schema-faq-answer\">They have conceded 17 touchdowns and allow 52.8% on third down, both the worst marks in the NFL.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-detari-4\"><strong class=\"schema-faq-question\">Is James Conner playing for Arizona?<\/strong> <p class=\"schema-faq-answer\">No. Conner is on injured reserve, as is Trey Benson.<\/p><\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><em>21+ | Gambling Problem? Call 1-800-GAMBLER | Signal probabilities and odds approximate at time of writing and subject to change<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Detroit have conceded 17 touchdowns, more than any team in the NFL, and allow opponents 52.8% on third down, also the worst mark in the league. Our Lions vs Cardinals prediction explains how they are still 2-2. They score. The Detroit Lions have 119 points and a 108.6 passer rating, and they have simply been&#8230;<\/p>\n","protected":false},"author":394,"featured_media":65586,"menu_order":0,"template":"","meta":{"_acf_changed":false,"_yoast_wpseo_focuskw":"lions vs cardinals prediction","_yoast_wpseo_title":"Lions vs Cardinals Prediction, Picks & Odds | Squawka","_yoast_wpseo_metadesc":"Lions vs Cardinals prediction, picks and odds for State Farm Stadium, where Detroit have conceded 17 touchdowns and still sit at .500.","footnotes":""},"tags":[375,364,350],"class_list":["post-65587","nfl-news","type-nfl-news","status-publish","has-post-thumbnail","hentry","tag-arizona-cardinals","tag-detroit-lions","tag-nfl"],"acf":{"external_featured_image_url":"","hide_featured_image_pattern":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Lions vs Cardinals Prediction, Picks &amp; Odds | Squawka<\/title>\n<meta name=\"description\" content=\"Lions vs Cardinals prediction, picks and odds for State Farm Stadium, where Detroit have conceded 17 touchdowns and still sit at .500.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.squawka.com\/us\/nfl\/nfl-news\/lions-vs-cardinals-prediction-picks-odds-week-5\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lions vs Cardinals Prediction, Picks &amp; 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