Nuno Espirito Santo’s side have collected four points from their opening two matches in Group G.
Spurs began by rescuing a 2-2 draw against Rennes, before sweeping Slovenian outfit Mura aside 5-1 with Harry Kane helping himself to a hat-trick.
That was the first of three consecutive wins for Tottenham, who have scored 10 goals during that span.
And importantly, Kane is off the mark in the Premier League having netted in Sunday’s victory at Newcastle, so the England captain will be eager to kick on with that weight now removed from his shoulders.
Standing in his way is Vitesse, who can leapfrog Spurs should they prevail at the Gelredome.
The Eredivisie side are in decent form, having won three of their last five in all competitions.
CLICK HERE to claim. 18+ only. *New members. £10 min deposit & bet on sportsbook, placed & settled at 1.5 min odds within 14 days of sign-up. Win part of E/W bets. 2 non-withdrawable £10 Free Bet Tokens: accept in 7 days, valid for 7 days from acceptance (ex. E/Ws & Multiples), stakes not returned. Bet Responsibly. BeGambleAware.org. Full T&Cs apply.
Vitesse vs Tottenham Hotspur: Match Stats
They may be back in business up front, but Tottenham still have concerns at the other end of the field.
In fact, Nuno’s side have now failed to keep a clean sheet in their last eight matches in all competitions.
That will encourage Vitesse who, by contrast, have found the net in each of their eight most recent outings.
Vitesse vs Tottenham Hotspur: Squawka Says
Scoreline prediction: Vitesse 1-3 Tottenham Hotspur
5:45 pm Thursday October 21
Vitesse 1-3 Tottenham HotspurEuropa Conference League