We are all set for a crucial clash in Group A at Ibrox.
Both sides are on four points and vying for second place behind runaway leaders Lyon.
And with Rangers concluding their group phase against the Ligue 1 side, the onus will be on them to get a positive result here.
They will also be keen to get Giovanni van Bronckhorst’s reign off to the best possible start, after the former midfielder replaced the outgoing Steven Gerrard last week.
Standing in their way is Sparta, who hold the edge on the head-to-head record, were 1-0 winners in the reverse fixture back in September.
Although, the Czech side have lost eight of their last 10 away matches in the Europa League.
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Rangers vs Sparta Prague: Match Stats
Rangers’ Scottish League Cup semi-final defeat by Hibernian on Sunday ended an unbeaten run of eight matches.
However, they have now kept just one clean sheet in their last 10 games.
Meanwhile, Sparta arrive in Glasgow having conceded seven goals without reply in their last two away from home.