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Liverpool vs Southampton Predictions, Tips and Odds: Reds on search for quadruple

Liverpool and Southampton meet in an FA Cup fifth-round showdown on Wednesday at 8pm (UK time).

The Reds come into this game having just won the EFL Cup for the 10th time, beating Chelsea 1-0 after extra-time. Liverpool have had mixed fortune in the FA Cup fifth round of late, alternating between progression (five) and elimination (four) in their last nine such ties. The Reds beat Norwich 2-1 in their last match in 2021/22, the only time they’ve reached the quarter-final of the competition under Jürgen Klopp, en route to winning the FA Cup.

Southampton, meanwhile, have progressed from three of their last four FA Cup fifth-round ties, including twice in the previous three seasons. However, they did lose against Grimsby Town at this stage of the competition last term.

Liverpool vs Southampton predictions

Liverpool vs Southampton: Predictions

Bet Prediction Bookmaker odds
BTTS? Yes 1/2 by BoyleSports
Correct Score Liverpool 4-1 Southampton 16/1 by BetMGM
First Goalscorer Luis Diaz 5/1 by Bet365

The stats behind our Liverpool vs Southampton predictions:

  • Both teams have scored in Liverpool’s last eight matches at home.
  • Liverpool have won their last six matches at home, three of the last four by a three-goal margin.
  • Liverpool have opened the scoring in three of their last four matches at home.

Liverpool vs Southampton match tip

Ché Adams to score anytime @ 11/4 with Star Sports

Ché Adams has been directly involved in four goals in his last three FA Cup appearances (two goals and two assists), twice as many as in his first 18 games in the competition (one goal and one assist).

Liverpool vs Southampton odds


*Odds correct as of 07:45 on February 28. 18+ only. BeGambleAware.

Liverpool have won each of their last four FA Cup meetings with Southampton, most recently a 3-0 fifth-round victory at Anfield in 1989/90. Furthermore, the Saints have lost their last six away games against Liverpool in all competitions and are winless in seven (one draw) since a 1-0 victory in the 2016/17 EFL Cup semi-final.

Liverpool vs Southampton team news

Liverpool team news

In  Out Doubtful
Joel Matip, Diogo Jota, Trent Alexander-Arnold, Alisson, Curtis Jones, Thiago Alcantara, Stefan Bajcetic, Ryan Gravenberch Darwin Nunez, Mohamed Salah, Dominik Szoboszlai, Wataru Endo

The injury problems aren’t getting any better for Liverpool, with Wataru Endo picking up a knock in the EFL Cup win over Chelsea, rendering him a doubt.  Ryan Gravenberch was taken off on a stretcher in that game, suffering an ankle ligament injury.

Top Scorer: Diogo Jota, Curtis Jones, Ryan Gravenberch, Luis Diaz, Darwin Nunez, Virgil van Dijk (1)

Card Magnet: Trent Alexander-Arnold, Ryan Gravenberch, Harvey Elliott, Bobby Clark (1)

Assist Ace: Conor Bradley (2)

Southampton team news

In  Out Doubtful
Ross Stewart, Juan Larios, Ryan Fraser, David Brooks

Russell Martin has a near-clean bill of health, but Ryan Fraser suffered a knee injury in Southampton’s defeat to Millwall at the weekend, joining Ross Stewart and Juan Larios on the sidelines. David Brooks is cup-tied, having already featured for Bournemouth in the FA Cup before his loan move.

Top Scorer: Sekou Mara (3)

Card Magnet: Adam Armstrong, Will Smallbone, Samuel Amo-Ameyaw, Tyler Dibling, Mason Holgate, Carlos Alcaraz, Samuel Edozie (1)

Assist Ace: Che Adams, Carlos Alcaraz (2)

How to live stream Liverpool vs Southampton online:

Bet365* streams a selection of FA Cup matches live for account holders.

To sign up for and live stream Liverpool vs Southampton, eligible readers outside the UK can follow the steps below.

  • Click on this link.
  • ‘Join now’ and enter details.
  • Log in and fund your account.
  • Navigate to the ‘In-Play’ link at the top of the homepage and select your desired event.

* Geo restrictions apply, 18+ only. Must have a funded account or placed a bet in the last 24 hours, BeGambleAware. All odds and offers within this article are accurate at the time of writing.

UK: This match is available for live broadcast in the UK on ITV1, with streaming available on the ITVX app and the ITV website.

Major European leagues you can watch on bet365**: La Liga, Serie A, Bundesliga, Eredivisie, Portuguese Primeira Liga, Ligue 1

**For local rights-based reasons, some of these leagues cannot be broadcast in certain locations (e.g. Serie A streams are inaccessible in Italy). Please check whether your country of residence is excluded.

Liverpool vs Southampton head-to-head

  • 28 May 2023 – Southampton 4-4 Liverpool – Premier League
  • 12 October 2022 – Liverpool 3-1 Southampton – Premier League
  • 17 May 2022 – Southampton 1-2 Liverpool – Premier League
  • 27 November 2021 – Liverpool 4-0 Southampton – Premier League
  • 8 May 2021 – Liverpool 2-0 Southampton – Premier League

Liverpool have won 10 of their previous 12 meetings with Southampton, with six of those matches seeing them score at least three goals.